Benjamin Leach, M.D.

818-660-4700
Benjamin Leach, M.D.
Medical Oncologist and Hematologist
Clinical Expertise
  • Hematology-Oncology
Other Languages Spoken
Spanish
Academic Appointments
  • Assistant Clinical Professor, Department of Medical Oncology & Therapeutics Research
Clinical Teams
Medical Oncology & Therapeutics Research

My own approach to patient care is mirrored by the culture at City of Hope — the cornerstone being compassion, innovation and collaboration.

Benjamin Leach, M.D., takes a passionate approach to cancer treatment incorporating leading-edge therapies from precision medicine to immunotherapy, with a relentless commitment to serving his patients and improving their quality of life.

"It's a privilege to be welcomed into patients' lives," he says.

Dr. Leach received his medical degree at Tulane University in New Orleans, completed his internship and residency at Los Angeles County + USC Medical Center and continued his training with a hematology/oncology fellowship at New York-Presbyterian Hospital/Weill Cornell Medical College. At Weill Cornell, he pursued his interest in targeted treatment, studying the WNT signaling pathway implicated in colorectal cancer development, for which he was awarded the Weill Department of Medicine Fellows Award in Research.

Dr. Leach treats patients at City of Hope's Mission Hills, California, facility.

Location

Education & Experience

Board Certifications

  • 2019, American Board of Internal Medicine, Oncology
  • 2019, American Board of Internal Medicine, Hematology
  • 2014, American Board of Internal Medicine

Degrees

  • 2011, M.D., Tulane University, New Orleans, Louisiana
  • 2005, B.S., biological sciences, University of Illinois, Chicago, Illinois

Fellowship

  • 2014–2017, Hematology and Oncology, New York-Presbyterian Hospital, Weill Cornell Medical College, New York, New York

Residency

  • 2011–2014, Intern and Resident, Department of Medicine, Los Angeles County + USC Medical Center, Los Angeles, California

Professional Experience

  • 2017–present, Assistant Clinical Professor, Department of Medical Oncology & Therapeutics Research, City of Hope, Mission Hills, CA

Awards & Memberships

Awards

  • 2017, Weill Department of Medicine Fellows Award in Research

Memberships

  • 2020, American Society of Clinical Oncology

Publications

  • Shen MJ, Gonzalez C, Leach B, Maciejewski PK, Kozlov E, Prigerson HG. An examination of Latino advanced cancer patients' and their informal caregivers' preferences for communication about advance care planning: A qualitative study. Palliat Support Care. 2020 Jun; 18(3): 277-284.
  • Rajurkar S, Mambetsariev I, Pharaon R, Leach B, Tan T, Kulkarni P, Salgia R. Non-Small Cell Lung Cancer from Genomics to Therapeutics: A Framework for Community Practice Integration to Arrive at Personalized Therapy Strategies. J Clin Med. 2020 Jun 15; 9(6): 1870.
  • Presant CA, Salgia R, Kulkarni P, Tiep BL, Sanani S, Leach B, Ashing K, Sandoval J, Sedrak MS, Landau S, Yeung S, Raz D, Subbiah S. Implementing Lung Cancer Screening and Prevention in Academic Centers, Affiliated Network Offices and Collaborating Care Sites. J Clin Med. 2020 Jun 11; 9(6): 1820.
  • Foronda M, Tarumoto Y, Schatoff EM, Leach BI, Diaz BJ, Zimmerman J, Goswami S, Shusterman M, Vakoc CR, Dow LE. Tankyrase inhibition sensitizes cells to CDK4 blockade. PLoS One. 2019 Dec 31; 14(12): e0226645.
  • Schatoff, EM, Goswami S, Zafra MP, Foronda M, Shusterman M, Leach BI, Katti A, Diaz BJ, Dow LE. Distinct Colorectal Cancer-Associated APC Mutations Dictate Response to Tankyrase Inhibition. Cancer Discov. 2019 Oct; 9(10): 1358-1371.
  • O’Rourke KP, Loizou E, Livshits G, Schato􀃠 EM, Baslan T, Manchado E, Simon J, Leach BI, Han T, Pauli C, Beltran H, Rubin MA, Dow LE, Lowe SW. Transplantation of engineered organoids enables rapid generation of metastatic mouse models of colorectal cancer. Nature Biotechnology. 2017 Jun; 35(6): 577-582.
  • Leach BI, Galletti G, Lam L, Tagawa ST. Mechanisms of resistance to systemic therapy in metastatic castration resistant prostate cancer. Cancer Treat Rev. 2017 Jun; 57: 16-27.
  • Schatoff EM, Leach BI, Dow LE. WNT Signaling and Colorectal Cancer. Curr Colorectal Cancer Rep. 2017 Apr; 13(2): 101-110.
  • Fedashchin A, Cernota WH, Gonzalez MC, Leach BI, Kwan N, Wesley RK, Weber JM. Random transposon mutagenesis of the Saccharopolyspora erythraea genome reveals additional genes influencing erythromycin biosynthesis. FEMS Microbiol Lett. 2015 Nov; 362(22)
  • Leach BI, Sun B, Petrovic L, Liu SV. Breast metastasis from nasopharyngeal carcinoma: A case report and review of the literature. Oncology Letters. 2013 June; 5 (6): 1859-61.

Ratings & Reviews

Ratings and reviews below are gathered from the Press Ganey Clinician and Group Consumer Assessment of Healthcare Providers and Systems (CG CAHPS) survey. CG CAHPS is a standardized survey that is used to measure a patient's experience in the physician office setting. Ratings are an average of all responses to questions about a provider's care, with five stars being the highest.
5.0
Provider explain in way you understand
5.0
Provider listen carefully to you
5.0
Show respect for what you say
4.9
Recommend this provider office
4.9
Know important info medical history
4.9
Spend enough time with you
4.9
Rate provider 0-10
04/26/26
Dr Leach is amazing - Verified patient
04/02/26
Dr Leach is just like [...]. Very kind, patient and empathetic. An Angel. - Verified patient
03/27/26
Both doctors I've seen there ([...] and Dr. Leach) were kind, compassionate, and listened to all of my health concerns and answered every question I had. They treated me with respect and talked TO me rather than AT me. (I saw them in separate appointments, NOT together) - Verified patient
03/16/26
I am very happy with the recommendations that doctor gives me. - Verified patient
03/15/26
Dr. Leach is an excellent oncologist and he has provided me with tremendous care. I owe my continued good health to him! There's no one better! - Verified patient