Matthew Lee, M.D.

Matthew Lee, M.D., MPH, is an assistant professor of medical oncology at City of Hope® Cancer Center Duarte, specializing in diagnosing and treating patients with lung cancer, including small cell lung cancer. His commitment to compassionate, patient-centered care is deeply rooted in his personal experience with cancer in his family, shaping his approach to individualized treatment plans for every patient.

Dr. Lee earned his medical degree from the State University of New York (SUNY) Downstate Medical School and completed an internal medicine residency at Hofstra University’s Northwell North Shore University Hospital. He further honed his expertise with a fellowship in hematology/oncology at the Albert Einstein College of Medicine/Montefiore Einstein Comprehensive Cancer Center. He also holds a Master of Public Health (MPH) in Epidemiology from SUNY Downstate, reflecting his strong interest in public health, socioeconomic determinants of health, and real-world data utilization.

His research focuses on targeted therapies, antibody-drug conjugates, cellular therapies, immunotherapy, and liquid biopsies (ctDNA) for risk stratification and diagnosis. He is actively involved in ECOG-ACRIN, ETCTN, Hoosier Cancer Research Network, and the Small Cell Lung Cancer Consortium.

An active researcher, Dr. Lee has published over a dozen peer-reviewed articles, contributed to multiple clinical trials, and participated in global health initiatives in Thailand, Uganda, and Honduras. His contributions to lung cancer research have been recognized with awards from the International Association for the Study of Lung Cancer.

Outside of work, Dr. Lee enjoys traveling the world, exploring new cultures and cuisines, running, and hiking.