An NCI-designated Comprehensive Cancer Center
John Yim

John H. Yim, M.D.

Surgical Oncologist
Clinical Expertise
Associate Professor, Division of Surgical Oncology, Department of Surgery
Referring Physicians/Colleagues: 626-218-3590

Clinical Teams

  • Breast Cancer
  • Surgery - Surgical Oncology
  • Thyroid and Parathyroid Cancers

Dr. Yim is a brilliant surgeon.
 - Patient

John Hosei Yim, M.D., joined City of Hope in 2008 after eight years at the University of Pittsburgh Medical Center, where he developed a breast and endocrine surgery practice and maintained an active laboratory research program. His practice at City of Hope is focused on breast and endocrine diseases, as he continues his research studies through Beckman Research Institute of City of Hope. 

Dr. Yim is developing new methods of molecular diagnosis for breast and thyroid nodules to see what treatments, including watchful waiting, are appropriate. He is pioneering the effort to treat cancer patients with baicalein, a natural product derived from a Chinese herb. Formulations of the baicalein are synthesized at City of Hope and clinical trial plans are underway.

A graduate of Yale University and Stanford University School of Medicine, Dr. Yim is praised by his patients for the time he spends educating each patient about their treatment options, as well as his superior surgical skills. He's been named one of America's Top Doctors by Castle Connolly, a "Top Doctor" in Pasadena magazine and a "Southern California Super Doctor" in Los Angeles magazine.


City of Hope Comprehensive Cancer Center, 1500 East Duarte Road

Duarte, CA 91010

Information listed here is obtained from Pubmed, a public database; City of Hope is not responsible for its accuracy.

1.  Meko JB, Yim JH, Tsung K, Norton JA. High cytokine production and effective antitumor activity of a recombinant vaccinia virus encoding murine IL-12. Cancer Research 1995; 55(21):4765-70.
2.  Tsung K, Yim JH, Marti W, Buller RM, Norton JA. Gene expression and cytopathic effect of vaccinia virus inactivated by psoralen and long-wave UV light. Journal of Virology 1996; 70(1):165-71.
3.  Yim JH, Barton P, Weber B, Radford D, Levy J, Monsees B, Flanagan F, Norton JA, Doherty GM. Mammographically detected breast cancer: Benefits of stereotactic core versus wire-localization biopsy. Ann Surg 1996; 223:688-700.
4.  Yim JH, Wick M, Philpott G, Norton JA, Doherty GM. Underlying pathology in mammary Paget’s disease. Ann Surg Oncol 1997; 4:287-92.
5.  Yim JH, Wu SJ, Casey MJ, Norton JA, Doherty GM. Interferon regulatory factor–1 gene transfer into an aggressive nonimmunogenic sarcoma suppresses the malignant phenotype and enhances immunogenicity in syngeneic mice. J Immunol 1997; 158:1284-92.
6.  Yim JH, Siegel BA, DeBenedetti MK, Norton JA, Lairmore TC, Doherty GM. Prospective study of the utility of somatastatin receptor scintigraphy in the evaluation of patients with multiple endocrine neoplasia type I. Surgery 1998; 124:1037-42.
7.  Yim JH, Wu SJ, Lowney JK, Vander Velde TL, Doherty GM. Enhancing in vivo tumorigenicity of B16 melanoma by overexpressing interferon regulatory factor-2: Resistance to endogenous interferon–gamma. J Interferon Cytokine Res 1999; 19:723-9.
8.  Carty SE, Roberts MM, Virji MA, Haywood L, Yim JH. The elevated parathormone level after concise parathyroid exploration for primary sporadic hyperparathyroidism. Surgery, 2002; 132(6):1086-92.
9.    Yim JH, Ro SH, Wu SJ, Lowney JK, Doherty GM. The role of interferon regulatory factor-1 and interferon regulatory factor -2 in growth inhibition of human breast carcinoma cell lines by interferon-gamma. J Interferon Cytokine Res. 2003;23(9):501-11.
10.  Hunt JL, Yim JH, Tometsko MJ, Finkelstein SF, Swalsky P, Carty SE. Loss of Heterozygosity of the VHL Gene Identifies Malignancy and Predicts Death in Follicular Thyroid Tumors. Surgery. 2003;134(6):1043-7.
11.  Kim PKM, Armstrong M, Liu Y, Yan P, Boucher B, Zuckerbraun BS, Billiar TR, and Yim JH. Interferon Regulatory Factor-1 (IRF-1) Expression Induces Apoptosis and Inhibits Tumor Growth in Mammary Cancer Cells.  Oncogene.  2004;23(5):1125-35
12.   Pizzoferrato E, Liu Y, Gambotto A, Armstrong MJ, Stang MT, Gooding WE, Alber SM, Shand SH, Watkins SC, Storkus WJ, Yim JH. Ectopic expression of interferon regulatory factor-1 promotes human breast cancer cell death and results in reduced expression of survivin. Cancer Research 2004; 64(22):8381-8.
13.  Park SY, Seol JW, Lee YJ, Cho JH, Kang HS, Kim IS, Park SH, Kim TH, Yim JH, Kim M, Billiar TR, Seol DW.  IFN-gamma enhances TRAIL-induced apoptosis through IRF-1. Eur J Biochem. 2004; 1(21):4222-8.
14.   Hunt JL, Carty SE, Yim JH, Murphy J, Barnes L, Allelic Loss in Parathyroid Neoplasia Can Help Characterize Malignancy. American Journal of Surgical Pathology. 2005; 29(8):1049-1055.
15.   Stang MT, Yim JH, Challinor SM, Bahl S, Carty SE. Hyperthyroidism after parathyroid exploration. Surgery. 2005 Dec;138(6):1058-64
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