Prajish Iyer, Ph.D.

Postdoctoral Fellow, Department of Systems Biology

Research Area

Molecular Mechanism of Genetic Alterations in Chronic Lymphocytic Leukemia

Prajish Iyer was awarded his Ph.D. in life sciences from Tata Memorial Cancer Centre, Advanced Center for Treatment Research and Education in Cancer (ACTREC), in India in 2018 for his thesis entitled “Genetic approaches to identify novel oncogenes in human cancer.”

During his Ph.D. period, he gained expertise in understanding the genomics of gallbladder, head and neck, lung cancer using next-generation sequencing technologies.

His work has been covered by Wellcome Trust news in India and other media outlets. Dr. Iyer joined the laboratory of Lili Wang, M.D., Ph.D., in February 2018, where he hopes to use his genomic expertise to understand the genetic alterations of chronic lymphocytic leukemia. His current work is focused on understanding the role of NOTCH signaling and the role of genetic alterations in chronic lymphocytic leukemia.

Education & Experience

Degrees

2017, Ph.D., Life Sciences , Tata Memorial Cancer Centre , ACTREC, India
2012, M.S., Biochemistry, Maharaja Sayajirao University of Baroda, India
2009, B.S., Biotechnology, University of Mumbai, India

Professional Experience

2018-present, Postdoctoral Fellow, Department of Systems Biology, City of Hope, Monrovia, CA

Awards & Memberships

Awards

2017, SAM Mistry Travel Grant Award for attending Cell Symposia
2017, Homi Bhabha National Institute Travel Grant Award for attending Cell Symposia
2016, Nature Reviews Best Poster Award in NextGen Genomics and Bioinformatics Technologies Conference
2016, Top Poster selected for presentation under Award Category in the India International Science Festival
2014, Nature Reviews Best Poster Award in NextGen Genomics and Bioinformatics Technologies Conference
2012, Best Poster Award Second Global Cancer Genomics Consortium: Second Annual Symposium Genomics Medicine in Cancer Research

Memberships

American Association for Cancer Research
Indian Association for Cancer Research, India
ATCC SDO Consensus Standards Partnership
International Society for Experimental Hematology

Publications

Chandrani P, Prabhash K, Prasad R, Sethunath V, Ranjan M, Iyer P, Aich J, Dhamne H, Iyer DN, Upadhyay P, Mohanty B, Chandna P, Kumar R, Joshi A, Noronha V, Patil V, Ramaswamy A, Karpe A, Thorat R, Chaudhari P, Ingle A, Choughule A, Dutt A. Drug-sensitive FGFR3 mutations in lung adenocarcinoma. Ann Oncol. 2017; 28:597-603. DOI: 10.1093/annonc/mdw636.

Iyer P, Barreto SG, Sahoo B, Chandrani P, Ramadwar MR, Shrikhande SV, Dutt A. Non-typhoidal Salmonella DNA traces in gallbladder cancer. Infect Agent Cancer. 2016; 11:12. DOI: 10.1186/s13027-016-0057-x..

Upadhyay P, Gardi N, Desai S, Sahoo B, Singh A, Togar T, Iyer P, Prasad R, Chandrani P, Gupta S, Dutt A. TMC-SNPdb: an Indian germline variant database derived from whole exome sequences. Database (Oxford). 2016; pii: baw104. DOI: 10.1093/database/baw104.

Chandrani P, Kulkarni V, Iyer P, Upadhyay P, Chaubal R, Das P, Mulherkar R, Singh R, Dutt A. NGS-based approach to determine the presence of HPV and their sites of integration in human cancer genome. Br J Cancer. 2015; 112:1958-1965.

Chandrani P, Upadhyay P, Iyer P, Tanna M, Shetty M, Raghuram GV, Oak N, Singh A, Chaubal R, Ramteke M, Gupta S, Dutt A. Integrated genomics approach to identify biologically relevant alterations in fewer samples. BMC Genomics. 2015; 16:936.