Anil Kumar, B.S., M.S., Ph.D.
Staff Scientist
Research Area
- Molecular Mechanisms of Immune Surveillance in B- and T-lymphoid Malignancies
- Identification of Alternative Treatment Approaches for High-risk Pediatric Lymphoid Malignancies
Duarte Cancer Center
Location
Duarte Cancer Center
1500 East Duarte Road
Duarte, CA 91010
Duarte, CA 91010
Education & Experience
2019, Ph.D., Biotechnology, National For Cell Science, Pune, India
2007, M.Sc., Biotechnology, Bangalore University, India
2005, B.Sc., Biotechnology, H.P. University Shimla, India
Awards & Memberships
- Member, American Society of Hematology (ASH) | 2025
- DBT International Travel Grant | Govt. of India | 2016
- Senior Research Fellowship (CSIR) | Govt. of India | 2014-2019
- Junior Research Fellowship (CSIR) | Govt. of India | 2012-2014
- Qualified CSIR-JRF Exam (Rank 29) | 2011
- Graduate Aptitude Test in Engineering (GATE-2011) | Qualified
- National Eligibility Test Lectureship (NET) | Qualified, 2010
Publications
- Chouhan, S.; Muhammad, N.; Usmani, D.; Khan, T.H.; Kumar, A. Molecular Sentinels: Unveiling the Role of Sirtuins in Prostate Cancer Progression. 2025, Int. J. Mol. Sci.
- Anil Kumar and Srividya Swaminathan. Type I Interferons: leukemia's old foe in the limelight again. 2024, Haematologica, (Editorial).
- Chouhan, S.; Kumar, A.; Muhammad, N.; Usmani, D.; Khan, T.H. Sirtuins as Key Regulators in Pancreatic Cancer: Insights into Signaling Mechanisms and Therapeutic Implications. 2024, Cancers.
- Chouhan, S.; Kumar, A.; Piprode, V.; Dasgupta, A.; Singh, S.; Khalique, A. Regulatory-Associated Protein of mTOR-Mediated Signaling: A Nexus Between Tumorigenesis and Disease. 2024, Targets.
- Anil Kumar, Adeleh Taghi Khani, Caroline Duault, et al., Intrinsic suppression of type I interferon production underlies the therapeutic efficacy of IL-15-producing natural killer cells in B-cell acute lymphoblastic leukemia. 2023, The Journal for ImmunoTherapy of Cancer.
- Adeleh Taghi Khani, Anil Kumar, Ashly Sanchez Ortiz, Kelly C. Radecki, Soraya Aramburo, Sung June Lee, Zunsong Hu, Behzad Damirchi, Mary Y. Lorenson, Xiwei Wu, Zhaohui Gu, William Stohl, Ignacio Sanz, Eric Meffre, Markus Müschen, Stephen J. Forman, Jean L. Koff, Ameae M. Walker & Srividya Swaminathan. Isoform-specific knockdown of long and intermediate prolactin receptors interferes with evolution of B-cell neoplasms. 2023, Nature Communications Biology.
- Anil Kumar, Adeleh Taghi Khani, Ashly Sanchez Ortiz, and Srividya Swaminathan. GM-CSF: A Double-Edged Sword in Cancer Immunotherapy. 2022, Frontiers in Immunology.
- Lekha Rani, Anil Kumar, Juilee Karhade, Garima Pandey, Adrita Guha, Gyan C. Mishra and Mohan R. Wani. IL-3 regulates the differentiation of pathogenic Th17 cells. 2022, European Journal of Immunology.
- Anil Kumar, Adeleh Taghi Khani, and Srividya Swaminathan. Harnessing Natural Killer Cell-Mediated Innate Immune Responses for Cancer Treatment: Advances and Challenges. 2022, Exploratory Research and Hypothesis in Medicine.
- Anil Kumar and Srividya Swaminathan. Natural Killer Cell Phenotype at Diagnosis of Acute Lymphoblastic Leukemia Predicts Disease Prognosis. 2021, J Vasc Med Surg.
- Anil Kumar, Adeleh Taghi Khani, Srividya Swaminathan. Type I interferons: One stone to concurrently kill two birds, viral infections and cancers. 2021, Current Research in Virological Science.
- Anil Kumar, Sung June Lee, Qiao Liu, Anthony KN Chan, Sheela Pangeni Pokharel, Jianhua Yu, Chun-Wei Chen, and Srividya Swaminathan. Generation and validation of CRISPR-engineered human natural killer cell lines for research and therapeutic applications. 2021, STAR Protocols.
- Caroline Duault*, Anil Kumar*, Adeleh Taghi Khani, Sung June Lee, Lu Yang, Min Huang, Christian Hurtz, Bryan Manning, Lucy Y. Ghoda, Tinisha McDonald, Norman J Lacayo, Kathleen M Sakamoto, Martin P. Carroll, Sarah K Tasian, Guido Marcucci, Jianhua Yu, Michael A Caligiuri, Holden T. Maecker, Srividya Swaminathan. Activated Natural Killer Cells Predict Poor Clinical Prognosis in High-risk B- and T- cell Acute Lymphoblastic Leukemia. 2021, Blood (Co-first authors).
- Kuan-Hui Ethan Chen, Mrinal Ghosh, Lorena Rivera, Samuel Lin, Anil Kumar, Srividya Swaminathan, Mary Y. Lorenson, Ameae M. Walker. Prolactin enhances T regulatory cell promotion of breast cancer through the long-form prolactin receptor. 2021, Translational Oncology.
- Vikrant Piprode, Kanupriya Singh, Anil Kumar, Snehal R Josh, Mohan R Wani. IL-3 inhibits rat osteoclast differentiation induced by TNF-α and other pro-osteoclastogenic cytokines. 2021, J Biosci.
- Anil Kumar, Rani L, Mhaske ST, Pote ST, Behera S, Mishra GC, Wani MR. IL-3 Receptor Expression on Activated Human Th Cells Is Regulated by IL-4, and IL-3 Synergizes with IL-4 to Enhance Th2 Cell Differentiation. 2020, J. Immunology.
- Parul Dutta, Sehbanul Islam, Srinadh Choppara, Pallabi Sengupta, Anil Kumar, Avinash Kumar, Mohan R Wani, Subhrangsu Chatterjee, and Manas Kumar Santra. The tumor suppressor FBXO31 preserves genomic integrity by regulating DNA replication and segregation through precise control of cyclin A levels. 2019, J. Biol. Chemistry.
- Garimella MG, Kour S, Piprode V, Mittal M, Anil Kumar, Rani L, Pote ST, Mishra GC, Chattopadhyay N, Wani MR. Adipose-Derived Mesenchymal Stem Cells Prevent Systemic Bone Loss in Collagen-Induced Arthritis. 2015, J. Immunology. Link