Sagus Sampath, M.D.
Radiation Oncologist
4.9 (124 RATINGS)
Clinical Expertise
- Lung Cancer
- Head and Neck Cancers
- Soft Tissue Sarcoma
- Melanoma
- Stereotactic Body Radiation Therapy
- Image-Guided Intensity Modulated Radiation Therapy (IG-IMRT) / TomoTherapy
- Stereotactic Radiosurgery
- Electronic Brachytherapy
- Intra-operative Radiation Therapy (IORT)
Research Area
- Stereotactic Body Radiation Therapy for Prostate and Lung Cancers
- Functional Imaging
- Immuno-oncology for Head and Neck Cancers
Other Languages Spoken
Spanish
Tamil
Academic Appointments
- Associate Clinical Professor, Department of Radiation Oncology
- Medical Director, Department of Radiation Oncology
Clinical Teams
Head and Neck Cancers
Lung Cancer
Mesothelioma
Sarcoma, Osteosarcoma and Bone Cancer
Skin Cancer and Melanoma
Spinal Tumors
Thoracic Oncology
Thyroid Cancer
Dr. Sampath Is wonderful in every way! A great doctor, easy to talk to, answers any and all questions plus gives you information you need to know, never makes you feel rushed, and makes you feel like he really cares. And my treatment was successful. - PatientSagus Sampath, M.D., is an associate clinical professor in the Department of Radiation Oncology and received his board certification in radiation oncology in 2011. He has been recognized by his peers as a "Rising Star" in Super Doctors 2020, and has been listed under Pasadena magazine "Top Doctors" from 2014 to present.
"Dr. Sampath Is wonderful in every way! A great doctor, easy to talk to, answers any and all questions plus gives you information you need to know, never makes you feel rushed, and makes you feel like he really cares. And my treatment was successful." was said by a patient.
In his spare time, Dr. Sampath enjoys playing South Indian classical music on the violin, and he is a USTA level 4.0 tennis player. He is also fluent in Spanish.
Location
Duarte Cancer Center
1500 East Duarte Road
Duarte, CA 91010
Duarte, CA 91010
Education & Experience
Diplomate, National Board of Medical Examiners
Diplomate, American Board of Radiology, Radiation Oncology
Active medical licenses in California and New Mexico
2001-2005, University of California, Irvine, Irvine, CA, M.D.
1997-2001, University of California Berkeley, Berkeley, CA, B.A., Molecular and Cell Biology
2009-2010, Chief Resident, Department of Radiation Oncology, University of Utah, Huntsman Cancer Hospital, Salt Lake City, UT
2008, Resident. Department of Radiation Oncology, University of Utah, Huntsman Cancer Hospital, Salt Lake City, UT
2006-2008, Resident, Department of Radiation Oncology, University of California Davis, Davis, CA
2005-2006, Intern, Department of Medicine, Alameda County Medical Center, Oakland, CA
2022-present, Medical Director, Department of Radiation Oncology, City of Hope, Duarte, CA
2012-present, Assistant Clinical Professor, Department of Radiation Oncology, City of Hope, Duarte, CA
2010-2012, Assistant Professor, Department of Radiation Oncology, University of New Mexico Cancer Center, Albuquerque, NM
Awards & Memberships
Awards
2015, Top Docs, Pasadena Magazine
American Brachytherapy Society Seattle Prostate Fellowship
ASTRO Advocacy Day 2010 Travel Grant
American Brachytherapy Society Seattle Prostate Fellowship
William Roentgen RSNA Research Award
2001, Phi Beta Kappa, University of California Berkeley
Memberships
2010-present, American Society of Clinical Oncology
2006-present, American Society of Therapeutic Radiology and Oncology
2006-2010, Association of Residents in Radiation Oncology
Publications
- Sampath S, Moerira D, Magharni E, Lee P, Massarelli E, Konylewski M. Myeloid Cell-Targeted STAT3 Inhibition Sensitizes Head and Neck Cancers to Radiotherapy and T cell-Mediated Immunity Journal of Clinical Investigation 2020 (in press).
- Frankel PH, Chung V, Tuscano J, Siddiqi T, Sampath S, Longmate J, Groshen S, Newman EM. Model of a Queuing Approach for Patient Accrual in Phase 1 Oncology Studies. JAMA News Open. 2020;3(5):e204787. doi:10.1001/jamanetworkopen 2020.4787
- Shinde A, Li R, Han C, Frankel P, Sampath S. Dos: metric predictors of genitourinary toxicity from a phase I trial of prostate bed stereotactic body radiation therapy. Practical Radiat Onc 2020 (in press).
- Chen BT, Jin T, Ye N, Mambetsariev I, Daniel E, Wang T, Wong CW, Rockne RC, Colen R, Holodny AI, Sampath S, Salgia R. Radiomic prediction of mutation status based on MR imaging of lung cancer brain metastases. Magn Reson Imaging. 2020 Mar 13 (epub ahead of print)
- Sampath S, Frankel P, et al. Stereotactic body radiation therapy to the prostate bed: results of a phase 1 dose escalation trial. Int J Radiat Oncol Biol Phys 2020 Mar 1;106(3):537-545
- Sampath S, Rahmanuddin S, Sahoo P, Frankel P, et al. Change in apparent diffusion coefficient is associated with local failure after stereotactic body radiation therapy for non-small cell lung cancer: a prospective clinical trial. Int J Radiat Oncol Biol Phys 2019 Nov 1;1-05(3):659-663
- Sampath S, Won H, Massarelli E, Li M, Frankel P, Vora N, Vora L, Magharni E, and Kortylewski M. Combined modality radiation therapy promotes tolerogenic myeloid cell populations and STAT3-related gene expression in head and neck cancer patients. Onco target 2018 Feb 2;9(13):11279-11290.
- Sampath S, Schultheiss TE, Wong J. Dose response and factors related to interstitial pneumonitis after bone marrow transplant. Int J Radiat Oncol Biol Phys 2005 Nov 1;63(3):876-84.
- Sampath S, Schultheiss TE, Ryu JK, et al. The role of adjuvant radiation in uterine sarcomas. Int J Radiat Oncol Biol Phys 2010 Mar 1;76(3):728-34.
- Sampath S, Schultheiss TE, Hitchcock YJ, et al. Radiotherapy and extent of surgical resection in retroperitoneal soft-tissue sarcoma: multi-institutional analysis of 261 patients. J Surg Oncol 2010 Apr 1;101(5):345-50.
- Sampath S, Schultheiss TE, Hitchcock YJ, et al. Pre-operative radiotherapy versus post-operative radiotherapy in soft-tissue sarcoma: multi-institutional analysis of 821 patients. Int J Radiat Oncol Biol Phys 2011 Oct 1;81(2):498-505.
- Schroeder TM, Liem B, Sampath S, et al. Early Breast cancer with positive margins: excellent local control with an upfront brachytherapy boost. Breast Cancer Res Treat 2012 Jul;134(2):719-25.
- Bauman JE, Austin M, Schmidt R, Kurland B, Vaezi A, Hayes DN, Mendez E, Parvathaneni U, Chai X, Sampath S, Martins RG. ERCC1 is a prognostic biomarker in locally advanced head and neck cancer: results from a randomized, phase II trial. Br J Cancer 2013 Oct 15;109(8):2096-105.
- Sorra A, Schroeder TM, Liem B, Thompson W, Sampath S. Predictive factors for radiation pneumonitis in patients receiving intensity-modulated radiation therapy for thoracic malignancy. J Nucl Med Radiat Ther 2013; 4:149.
- Sun V, Kim J, Williams AC, Raz D, Sampath S, Ferrell B. Quality of Life and Symptoms Following Stereotactic Body Radiotherapy in Early Stage Lung Cancer Patients. Journal of Community and Supportive Oncology. 2014 Nov;12(11):407-414.
- Sampath S, Hall MH, and Schultheiss TE. Definitive chemotherapy and radiotherapy in patients with stage II non-small cell lung cancer: a population-based outcomes study. Lung Cancer 2015 Oct;90(1):61-4.
- Sampath S and Gaffney DK. Role of Radiotherapy Treatment of Uterine Sarcoma. Best Prac Res Clin Obstet Gynaecol 2011 Dec;25(6):761-72.
Ratings & Reviews
Ratings and reviews below are gathered from the Press Ganey Clinician and Group Consumer Assessment of Healthcare Providers and Systems (CG CAHPS) survey. CG CAHPS is a standardized survey that is used to measure a patient's experience in the physician office setting. Ratings are an average of all responses to questions about a provider's care, with five stars being the highest.
5.0
Spend enough time with you
4.9
Recommend this provider office
4.9
Provider explain in way you understand
4.9
Provider listen carefully to you
4.9
Know important info medical history
4.9
Show respect for what you say
4.9
Rate provider 0-10
04/25/25
The doctors, nurses and medical personnel were great! [...] - Verified patient
04/13/25
I don't get enough information - Verified patient
02/21/25
Dr Sampath is simply the best of the best. He always patiently explain my condition/test results in a way that I will have a complete understanding at each visit. After meeting with Dr Sampath, I always feel at ease and relief. His great knowledge in the field and genuine care for his patients are what make him the best doctor. - Verified patient
02/18/25
Dr. Sampath was very professional and explained my health issue is easy terms to understand. He asked several times if I had any questions. He was emphatic to my issues and concerns. - Verified patient
02/18/25
Overall, everyone we encounter at City of Hope are fabulous! - Verified patient