An NCI-designated Comprehensive Cancer Center
Yiming Wu - Systems Biology

Yiming Wu, Ph.D.

Postdoctoral Fellow, Department of Systems Biology
Research Focus
  • Genetic alterations and CLL biology
  • RNA splicing dysregulation and oncogenesis

Research Teams

  • Systems Biology
Wu L*, Chen J*, Wu Y*, Zhang B, Cai X, Zhang Z, Wang Y, Si L, Xu H, Zheng Y, Zhang C, Liang C, Li J, Zhang L, Zhang Q, Zhou D. Precise and combinatorial PEGylation generates a low-immunogenic and stable form of human growth hormone. J Control Release 2017, 249, 84-93. (*authors contributed equally) 
Wu Y, Zhu H, Zhang B, Liu F, Chen J, Wang Y, Wang Y, Zhang Z, Wu L, Si L, Xu H, Yao T, Xiao S, Xia Q, Zhang L, Yang Z, Zhou D. Synthesis of site-specific radiolabeled antibodies for radioimmunotherapy via genetic code expansion. Bioconjug Chem 2016, 27 (10), 2460-2468. 
Zhang Z, Xu H, Si L, Chen Y, Zhang B, Wang Y, Wu Y, Zhou X, Zhang L, Zhou D. Construction of an inducible stable cell line for efficient incorporation of unnatural amino acids in mammalian cells. Biochem Biophys Res Commun 2017, 489 (4), 490-496. 
Si L, Xu H, Zhou X, Zhang Z, Tian Z, Wang Y, Wu Y, Zhang B, Niu Z, Zhang C, Fu G, Xiao S, Xia Q, Zhang L, Zhou D. Generation of influenza A viruses as live but replication-incompetent virus vaccines. Science 2016, 354 (6316), 1170-1173. 
Zhang B, Yang Q, Chen J, Wu L, Yao T, Wu Y, Xu H, Zhang L, Xia Q, Zhou D. CRISPRi-manipulation of genetic code expansion via RF1 for reassignment of amber codon in bacteria. Sci Rep 2016, 6, 20000. 
Zheng Y, Yu F, Wu Y, Si L, Xu H, Zhang C, Xia Q, Xiao S, Wang Q, He Q, Chen P, Wang J, Taira K, Zhang L, Zhou D. Broadening the versatility of lentiviral vectors as a tool in nucleic acid research via genetic code expansion. Nucleic Acids Res 2015, 43 (11), e73. 
Zhang B, Xu H, Chen J, Zheng Y, Wu Y, Si L, Wu L, Zhang C, Xia G, Zhang L, Zhou D. Development of next generation of therapeutic IFN-alpha2b via genetic code expansion. Acta Biomater 2015, 19, 100-11. 
Yu M, Si L, Wang Y, Wu Y, Yu F, Jiao P, Shi Y, Wang H, Xiao S, Fu G, Tian K, Wang Y, Guo Z, Ye X, Zhang L, Zhou D. Discovery of pentacyclic triterpenoids as potential entry inhibitors of influenza viruses. J Med Chem 2014, 57 (23), 10058-71.
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