Esophageal Cancer Research at City of Hope

May 25, 2025

This page was reviewed under our medical and editorial policy by Jae Y. Kim, M.D., associate professor, Division of Thoracic Surgery, Department of Surgery, City of Hope® Cancer Center Duarte

Getting treated for esophageal cancer at City of Hope® means you’re steps away from labs where new treatments are being developed every day.

Esophageal Cancer Research Projects

Our clinicians and researchers frequently collaborate to develop and evaluate new therapies designed to improve survival and quality of life.

Some of our current research projects include:

  • Evaluating telomelysin and definitive chemoradiation for patients with locally advanced esophageal and gastroesophageal adenocarcinoma who aren’t surgery candidates
  • Assessing M6620 and irinotecan in patients with progressive TP53 mutant gastric and gastroesophageal junction cancer
  • Analyzing gastrointestinal specimens prospectively to evaluate genetic and epigenetic markers

Esophageal Cancer Clinical Trials

City of Hope patients have access to a wide variety of clinical trials, ranging from new chemotherapy and targeted therapies to novel surgical techniques and new radiation approaches — all focused on enhancing treatment, detection and prevention of esophageal cancer.

Browse through some of City of Hope’s clinical trials and research projects.

(877) 460-4673