Pediatric Stem Cell Transplant Research
July 23, 2025
This page was reviewed under our medical and editorial policy by Anna Pawlowska, M.D., clinical professor, and Nicole Karras, M.D., associate clinical professor, Department of Pediatrics, City of Hope® Cancer Center Duarte.
City of Hope has long been at the forefront of pediatric stem cell transplant research. Our researchers, clinicians and scientists have taken their advancements straight to the clinic, providing lifesaving treatments for children with cancer and other diseases.
City of Hope has developed breakthroughs specifically with pediatric patients in mind to minimize the side effects of childhood bone marrow and stem cell transplants.
Our Childhood Stem Cell Transplant Research Highlights
City of Hope is a leader in pediatric stem cell transplants, with the following among the projects we’ve researched in the past or are currently studying:
- Evaluating the use of hematopoietic stem cell transplant (HSCT) for conditions including blood cancers, sickle cell disease, thalassemia, solid tumors and inherited bone marrow failure syndromes
- Investigating different types of bone marrow transplants for children, including allogeneic, autologous and umbilical
- Researching how to reverse muscle loss in pediatric patients who undergo stem cell transplants
- Evaluating new ways to help prevent and treat side effects like graft versus host disease (GVHD)
Pediatric Stem Cell Transplant Clinical Trials
Compassionate patient care means a commitment to research. Not only do our clinical trials give current childhood cancer and blood disorder patients access to promising, leading-edge bone marrow transplants, but they also improve overall care for future patients worldwide.