Wei-Hsien Hou, M.D.

(877) 524-4673
Wei-Hsien Hou, M.D.
Radiation Oncologist
Clinical Expertise

Radiation Oncology

Other Languages Spoken
Taiwanese
Mandarin
Academic Appointments
  • Assistant Clinical Professor, Department of Radiation Oncology
Clinical Teams
Radiation Oncology

Wei-Hsien Hou, M.D., is an assistant clinical professor of radiation oncology at City of Hope® San Bernardino, where he treats patients undergoing radiation therapy for a wide variety of cancer types.

Dr. Hou combines a patient-centered approach with his deep expertise in innovative technologies and techniques. His goal is to help people make informed decisions about their care so they can overcome cancer and maintain their quality of life.

After earning his medical degree from the St. Louis University School of Medicine in Missouri, Dr. Hou completed a preliminary-year internship in internal medicine at the St. Louis University Hospital, a residency in radiation oncology at City of Hope Cancer Center Duarte.

Dr. Hou has published articles in more than a dozen peer-reviewed journals, including Mutation Research and the International Journal of Gynecological Cancer, and presented his work at conferences both in and outside the United States.

Location

Education & Experience

Board Licensure

  • Medical Board of California, Physician and Surgeon License#: A129865, Active
  • Guam Board of Medical Examiner License#: M–2364, Active
  • Drug Enforcement Agency, FH4633118, Active
  • Board Certification: American Board of Radiology, Radiation Oncology, issued on 5/7/19

Degrees

  • 2012, Doctor of Medicine, Saint Louis University School of Medicine, St. Louis, Missouri
  • 2012, Doctor of Philosophy, Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St. Louis, Missouri

Internship

  • 2022, Clinical Internship, Cardinal Tien Hospital, New Taipei City, Taiwan

Residency

  • 2018, Residency, Radiation Oncology, City of Hope, Duarte, California
  • 2013, Residency, Internal Medicine PGY–1, Saint Louis University School of Medicine, St. Louis, Missouri

Professional Experience

  • 2024–present, Assistant Clinical Professor, Department of Radiation Oncology, City of Hope, San Bernardino, California
  • 2023–2024, Radiation Oncologist, Guam Regional Medical City, Guam
  • 2018–2021, Assistant Clinical Professor, Department of Radiation Oncology, City of Hope, Antelope Valley, California

Publications

  • Hou WH, Chen MB, Chou, R, Chen AY. (2023) “Intra-fractional corrections and clinical outcomes in frameless image-guided radiosurgery for trigeminal neuralgia.” Journal of Radiosurgery and SBRT (manuscript accepted for publication)
  • Wang YJ, Huang CY, Hou WH, Yu HJ, Lai MK, Liu SP, Pu YS, Cheng JC. (2020) “Simplified Predictive Nomogram for Postprostatectomy Patients Treated with High-dose Salvage Intensity Modulated Radiation Therapy.” Research Square, doi:10.21203/rs.3.rs-136186/v1. PPR:PPR258896.
  • Tien Y, Tsai CL, Hou WH, Chiang Y, Hsu FM, Tsai YC and Cheng JC. (2020) “Targeting human epidermal growth factor receptor 2 enhances radiosensitivity and reduces the metastatic potential of Lewis lung carcinoma cells.” Radiation Oncology, 15(1), 1-11, PMID: 32143669
  • Hou WH, Chen SS and Yu X. (2019) “Poly-ADP ribosylation in DNA damage response and cancer therapy.” Mutation Research – Reviews, Apr-Jun;780:82-91, PMID: 31395352
  • Shinde A, Hou WH, Han C, Glaser S, Chao J, Woo Y, Wong J, Chen YJ. (2019) “Reduced acute and late toxicities with intensity-modulated radiation therapy compared to three-dimensional conformal radiation therapy in post-operative gastric cancer.” Journal of Radiation Oncology. 8(1), 73-80
  • Hou WH, Schultheiss TE, Wong JY, Wakabayashi MT, and Chen YJ. (2018) “Surgery versus Radiation Treatment for High-Grade Neuroendocrine Cancer of Uterine Cervix.” International Journal of Gynecological Cancer, Jan;28(1):188-193, PMID: 29206662
  • Li R, Hou WH, Chao J, Woo Y, Glaser S, Amini A, Nelson R, Chen YJ. (2018) “Chemoradiation improves survival compared to chemotherapy alone in unresected, non-metastatic gastric cancer” Journal of the National Comprehensive Cancer Network, Aug;16(8):950-958, PMID: 30099371
  • Hou WH, Huang CY, Wang CC, Lan KH, Chen CH, Yu HJ, Liu SP, Lai MK, Pu YS, and Cheng JC. (2017) “Impact of androgen-deprivation therapy on the outcome of dose-escalation prostate cancer radiotherapy without elective pelvic irradiation.” Asian Journal of Andrology, 19(5):596, PMID: 27506334
  • Hou WH, Wang CW, Tsai CL, Hsu FM, and Cheng JC. (2016) “The ratio of weight Loss to planning target volume significantly impacts setup errors in nasopharyngeal cancer patients undergoing helical Tomotherapy with daily MVCT.” Radiology and Oncology, 50(4):427-432, PMID: 27904451
  • Hsu FM, Hou WH, Huang CY, Wang CC, Tsai CL, Tsai YC, Yu HJ, Pu YS, and Cheng JC. (2016) “Differences in toxicity and outcome associated with circadian variations between patients undergoing daytime and evening radiotherapy for prostate adenocarcinoma.” Chronobiology International, 33(2):210-9, PMID: 26818960.
  • Wang YJ, Huang CY, Hou WH, Wang CC, Lan KH, Yu HJ, Lai MK, Liu SP, Pu YS, and Cheng JC. (2016) “Dual-timing PSA as a biomarker for patients with salvage intensity modulated radiation therapy for biochemical failure after radical prostatectomy.” Oncotarget, 7(28):44224-44235, PMID: 27317764.
  • Huang SS, Chen CL, Huang FW, Hou WH, and Huang JS. (2016) “DMSO Enhances TGF-β Activity by Recruiting the Type II TGF-β Receptor from Intracellular Vesicles to the Plasma Membrane.” Journal of Cellular Biochemistry, 9999:1-12, PMID: 26587792.
  • Wang YJ, Huang CY, Hou WH, Wang CC, Lan KH, Yu HJ, Lai MK, Liu SP, Pu YS, and Cheng JC. (2015) “The outcome and prognostic factors for lymph node recurrence after node-sparing definitive external beam radiotherapy for localized prostate cancer.” World Journal of Surgical Oncology, 13:312, PMID: 26545980.
  • Zhu M, Bharat S, Michalski JM, Gay HA, Hou WH, and Parikh PJ. (2013) “Adaptive Radiation Therapy for postprostatectomy patients using real-time electromagnetic target motion tracking during external beam radiation therapy.” International Journal of Radiation Oncology Biology Physics, 85(4):1038–1044, PMID: 23021439.
  • Hou WH, Daly ME, Lee NY, Farwell G, Luu Q and Chen AM. (2012) “Racial Disparities in the Use of Voice-Preservation Therapy for Locally Advanced Laryngeal Cancer.” Archives of Otolaryngology-Head & Neck Surgery, 138(7):644-649. PMID: 22801888.
  • Hou WH, Liu IH, Huang SS, and Huang JS. (2012) “CRSBP-1 Ligands Induce Contraction of the ER Network in Lymphatic Endothelial Cells.” FEBS Letter, 586(10):1480-1487, PMID: 22673514.
  • Hou WH, Liu IH, Tsai CC, Johnson FE, Huang SS, and Huang JS. (2011) “CRSBP-1/LYVE-1 Ligands Disrupt Lymphatic Intercellular Adhesion by Inducing Tyrosine Phosphorylation and Internalization of VE-cadherin.” Journal of Cell Science. 124(8):1231-1244, PMID: 21444752.
  • Chen CL, Hou WH, Liu IH, Hsiao G, Huang SS, and Huang JS. (2009) Inhibitors of Clathrin-dependent Endocytosis Enhance TGF-beta Signaling and Responses. Journal of Cell Science. 2009 Jun; 122(11):1863-1871, PMID: 19461075.
  • Sprague R, Bowles E, Stumpf M, Ricketts G, Freidman A, Hou WH and Stephenson A. Lonigro A. (2005) “Rabbit Erythrocytes Possess Adenylyl Cyclase Type II that is Activated by the Heterotrimeric G Proteins Gs and Gi.” Pharmacological Reports. 57(Suppl):222-228, PMID: 16415502.
  • Liu YH, Wu HC, Lin HM, Hou WH and Lu KL. (2003) “Crystal Engineering toward Intersecting Channel in a Interpenetrated Diamondoid network based on a net-to-net H-bonding Interaction.” Chemical Communication. 7(1):60-61, PMID: 12610965.

Ratings & Reviews

Ratings and reviews below are gathered from the Press Ganey Clinician and Group Consumer Assessment of Healthcare Providers and Systems (CG CAHPS) survey. CG CAHPS is a standardized survey that is used to measure a patient's experience in the physician office setting. Ratings are an average of all responses to questions about a provider's care, with five stars being the highest.
5.0
Recommend this provider office
5.0
Provider listen carefully to you
5.0
Show respect for what you say
4.9
Provider explain in way you understand
4.9
Spend enough time with you
4.8
Know important info medical history
4.8
Rate provider 0-10
04/21/26
Very cordial and professional - Verified patient
01/30/26
Great staff. - Verified patient
01/30/26
Excellent person, very professional solved my doubts, I felt comfortable. - Verified patient
01/15/26
All good - Verified patient
12/02/25
Very clear, specific, direct and with a lot of professionalism. - Verified patient