Ping H. Wang, M.D.

- Bone Health
- Cancer Related Endocrinopathies
- Diabetes
- Endocrine Tumors
- Endocrinology
- Thyroid Tumors
- Diabetes & Metabolism
- Professor and Chair, Department of Diabetes, Endocrinology & Metabolism
Location
Orange County Lennar Foundation Cancer Center
Irvine, CA 92618
Education & Experience
2009, American Board of Endocrinology, Diabetes, and Metabolism
2002, American Board of Internal Medicine
1984, M.D., Kaohsiung Medical College, Kaohsiung, Taiwan
1985, S.M., Epidemiology, Harvard School of Public Health, Boston, MA
1991-1994, Endocrinology and Metabolism, Joslin Diabetes Center, and Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA
1985-1988, Joslin Diabetes Center, Section on Metabolism, Harvard Medical School, Boston, MA
1988-1991, Department of Medicine, Boston VA Medical Center and Tufts University School of Medicine, Boston, MA
1988-1991, Department of Medicine, Boston VA Medical Center and Tufts University School of Medicine, Boston, MA
2020-present, Chair, Department of Diabetes, Endocrinology & Metabolism, City of Hope, Duarte, CA
2011-2020, Director, UC Irvine Health Diabetes Center, Irvine, CA
2006-2020, Professor with Tenure, Department of Medicine, Department of Physiology and Biophysics, University of California Irvine, Irvine, CA
2005-2020, Director, UC Irvine Center for Diabetes Research and Treatment, Irvine, CA
2003-2020, Chief, Division of Endocrinology, Diabetes, and Metabolism, UC Irvine, Irvine, CA
2004-2011, Director, Joslin Diabetes Center at UC Irvine, Irvine, CA
2000-2006, Associate Professor with Tenure, Department of Medicine, Department of Biological Chemistry, Department of Physiology and Biophysics, University of California Irvine, Irvine, CA
2002-2005, Director, Center for Cardiovascular Hormone Research, UC Irvine, Irvine, CA
2001-2002, Acting Chief, Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, University of California Irvine, Irvine, CA
1994-2000, Assistant Professor, Department of Biological Chemistry
University of California Irvine, Irvine, CA1994-2000, Assistant Professor, Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, University of California Irvine, Irvine, CA
Awards & Memberships
Awards
2015-2020, Top Doctors, Orange Coast Magazine
2015-2020, Super Doctors, LA Magazine
2007-2020, Best Doctors in America, BestDoctors Inc.
2002-2020, America’s Top Doctors, Castle Connolly Medical LTD, NY
1993, Juvenile Diabetes Foundation Research Fellowship Award
1987, Juvenile Diabetes Foundation Research Fellowship Award
1984, Best Intern Award, Kaohsiung Medical College
Memberships
American Medical Association, Endocrine Society
American Federation of Clinical Research
American Diabetes Association, American Heart Association
1995-2020, Chao Family Comprehensive Cancer Center University of California
Publications
- Chen Y-H, Su C-C, Wu D, Lock LF, Donovan PJ, Kayala MA, Baldi P, Lee HC, Chen Y, Wang PH. Mitochondrial Akt Signaling Modulated Reprogramming of Somatic Cells. Scientific Reports, 2019 9(1):9919.
- Kedaigle AJ, Fraenkel E, Atwal RS, Wu M, Gusella JF, MacDonald ME, Kaye JA, Finkbeiner S, Mattis VB, Tom CM, Svendsen C, King AR, Chen Y, Stocksdale JT, Lim, RG, Casale M, Wang PH, Thompson LM, Akimov SS, Ratovitski T, Arbez N, Ross CA. Bioenergetic deficits in Huntington's disease iPSC-derived neural cells and rescue with glycolytic metabolites. Hum Mol Genet. 2019 Feb 15. pii: ddy430.
- Chalkia D, Chang Y-C, Derbeneva O, Lvova, M, Wang PH, Mishmar D, LiuX, Singh L, Chuang L-M, Wallac DC. Mitochondrial DNA Associations with East Asian Metabolic Syndrome. BBA-Bioenergetics, 2018; 1859;878-892.
- Zhou Y, Chen Y , Hu Y, Yu L, Tran K, Giedzinski E, Ru N, Gau A, Pan F, Qiao J, Atkin N, Ly K, Lee N, Siegel E, Linskey M, Wang P, Limoli C. The role of EGFR double minutes in modulating the response of malignant gliomas to radiotherapy. Oncotarget 2017; 8:80853-68.
- Fan W, Lee D, Choi S, Billimek J, Wang PH. The Changing Landscape of Diabetes Prevalence among First-Generation Asian Immigrants in California from 2003 to 2013. BMJ Open Diabetes Research and Care 2017; 5:e000327.
- Pedersen BA, Wang W, Taylor JF, Khattab O, Chen Y-H, Edwards RA, Yazdi, P, Wang PH. Hepatic proteomic analysis revealed altered metabolic pathways in insulin resistant Akt1+/-/Akt2-/- mice. Metabolism 2015; 64(12):1694-1703.
- Pedersen BA, Wang W, Yazdi A, Taylor JF, Khattab O, Chen Y-H, Chen Y, Wang PH. Novel remodeling of the mouse heart mitochondrial proteome in response to acute insulin stimulation. Nutr Metab Cardiovasc Dis. 2015; 25(12):1152-8.
- Chen Y, Chernyavsky A, Weber R, Grando SA, Wang PH. Critical role of FcRn in the pathogenic action of anti-mitochondrial autoantibodies synergizing with anti-desmoglein autoantibodies in pemphigus vulgaris. J Biol Chem. 2015; 290:23826-37.
- Ke C, Ru N, Chen Y, Yu L, Siegel ER, Linskey ME, Wang PH, Xing J, Zhou YH. Cell context-dependent dual effects of EFEMP1 stabilizes subpopulation equilibrium in responding to changes of in vivo growth environment. Oncotarget 2015; 6(31):30762-72.
- Yazdi A, Pedersen BA, Taylor JF, Khattab O, Chen Y-H, Chen Y, Jacobsen SE, Wang PH. Increasing nucleosome occupancy is correlated with an increasing mutation rate so long as DNA repair machinery is intact. PLoS One 2015; 10(8):e0136574.
- Yazdi A, Pedersen BA, Taylor JF, Khattab O, Chen Y-H, Chen Y, Jacobsen SE, Wang PH. Nucleosome organization in human embryonic stem cells. PLoS One 2015; 10 (8): e0136314.
- Chernyavsky A, Chen Y, Wang PH, Grando SA. Pemphigus vulgaris antibodies target the mitochondrial nicotinic acetylcholine receptors that protect keratinocytes from apoptolysis. Int Immunopharmacol. 2015; 29(1): 76-80.
- Ke C, Tran K, Chen Y, Di Donato AT, Yu L, Hu Y, Linskey ME, Wang PH, Limoli C, Zhou YH. Linking differential radiation responses to glioma heterogeneity. Oncotarget. 2014; 5(6): 1657–1665.
- Deng W, Leu HB, Chen Y, Chen YH, Epperson CM, Juang C, Wang PH. Protein Kinase B (PKB/Akt1) Formed Signaling Complexes with Mitochondrial Proteins and Protected against Glycolytic Energy Impairment in Stressed Cardiomyocytes. Endocrinology. 2014; 155(5):1618-28.
- Yazdi PG, Moradi H, Yang JY, Wang PH, Vaziri ND. Skeletal muscle mitochondrial depletion and dysfunction in chronic kidney disease. Int J Clin Exp Med. 2013; 6(7):532-9.
- Upadhyay S, Eckel-Mahan K, Mirbolooki M, Tjong I, Griffey S, Schmunk G, Koehne A, Halbout B, Iadonato S, Pedersen B, Borrelli E, Wang PH, Mukherjee J, Sassone-Corsi P, Chandy KG. Selective Kv1.3 channel blocker as therapeutic for obesity and insulin resistance. Proc Natl Acad Sci USA. 2013; 110(24):E2239-48.