Boryana Eastman, M.D., Ph.D.
Radiation oncologist Boryana Eastman, M.D., Ph.D., approaches patient care as a true partnership. She walks patients through their options, assists them in choosing what is right for them, and supports them throughout treatment. She has wanted to become a physician since she was a child and enjoys spending time with and listening to the people in her care.
Dr. Eastman, who is fluent in Bulgarian, received her PhD at UC San Diego in Biomedical sciences, focusing on breast cancer metastases. She continued her training there as a physician and pursued an internship in internal medicine. During her residency in Radiation Oncology at the University of Washington, she became interested in the treatment of cancers that spread to the brain. In her clinical practice, she focuses on treating cancer while maintaining quality of life.
In her free time, she is an enthusiast for the outdoors and enjoys hiking, camping, and traveling. At home she loves cooking and trying new foods.
- 2016, M.D., University of California, San Diego, La Jolla, California
- 2012, Ph.D., Biomedical Sciences, University of California, San Diego, La Jolla, California
2017, Radiation Oncology Residency, University of Washington, Seattle, WA
2016 - 2017, Internal Medicine Internship, University of California, San Diego, La Jolla, CA
- Eastman, B.M., Hippe, D., Wootton, L., Nyflot, M., Thompson, M., Pollack, S., Kim, E.Y., Spraker, M.B. 2021.Treatment at a high-volume center may mitigate the importance of socio-economic factors on overall survival in soft tissue sarcoma. BMC Cancer 21(1):620. PMID 34039294
- Eastman, B.M., Saigal, R., Hofstetter, C.P., Foote, M., Mayr, N.A., Lo, S.S. 2021. Commentary: Prognostic Factors Associated with Surviving Less than 3 Months vs Greater than 3 Years Specific to Spine SBRT and Late Adverse Effect. Neurosurgery. 88(5):E406-E407. PMID 33582789
- Eastman, B.M., Vinyak, V., Lo, S., Graber, J. 2020. Stereotactic radiosurgery in the treatment of adults with metastatic brain tumors. J Neurosurg Sci. (PMID 32270945)
- Badiyan, S, Kaiser, A, Eastman, B., Forsthoefel, M., Zeng, J., Unger, K., Chuong, M. 2019. Immunotherapy and Radiation Therapy for Gastrointestinal Malignancies: Hope of Hype? Transl Gastroenterol Hepatol. (PMID 32258525)
- Hu, J., Jo, M., Eastman, B.M., Gilder, A.S., Bui, J.D., Gonias, S.L. 2014. uPAR induces expression of transforming growth factor beta and interleukin-4 in cancer cells to promote tumor-progressive conditioning of macrophages. Am J Pathol 184(12):3384-93 (PMID 25310970)
- Eastman, B.M., Jo, M., Webb, D.L., Takimoto, S., Gonias, S.L. 2012. A transformation in the mechanism by which the urokinase receptor signals provides a selection advantage for estrogen receptor-expressing breast cancer cells in the absence of estrogen. Cell Signal 24(9):1847-55 (PMID 22617030)
- Eastman, B.M.*, Jo, M.*, Webb, D.L., Stoletov, K., Klemke, R., Gonias, S.L. 2010. Cell Signaling by Urokinase type Plasminogen Activator Receptor Induces Stem Cell-like Properties in Breast Cancer Cells. Cancer Res 70(21):8948-58 * equal contribution (PMID 20940399)
- Jo, M., Lester, R.D., Montel, V., Eastman B., Takimoto, S., Gonias, S.L. 2009. Reversibility of Epithelial-Mesenchymal Transition (EMT) Induced in Breast Cancer Cells by Activation of Urokinase Receptor-Dependent Cell Signaling, J Biol Chem 284(34):22825-33 (PMID 19546228)
- Eastman, B.M., Kane, G.M. Trim one’s (E)wings – how much is enough? 2020. Gray Zone Report. Int J Radiat Oncol Biol Phys
- Eastman, B.M., McGranahan, T., Cimino, P.J., Halasz, L.M. Craniospinal Irradiation in Patients Diagnosed with Glioblastoma with Primitive Neuroectoderm Features (GBM/PNET) Prevents Distant Intracranial and Leptomeningeal Recurrences. 2020. Eastman, B.M., McGranahan, T., Cimino, P.J., Halasz, L.M. ASCO 2020 Annual Meeting, Chicago, IL. Retrieved from “https://meetinglibrary.asco.org/record/190042/abstract”
- Eastman, B.M. 2016. The Effect of Deep Inspiration Breath Hold (DIBH) Intensity-Modulated Radiation Therapy (IMRT) on Sparing Healthy Tissues in the Treatment of Lymphoma Involving the Mediastinum. UC San Diego: School of Medicine. Retrieved from “https://escholarship.org/uc/item/69s6k84k”
- Eastman, B.M. 2012. The role of uPAR in inducing a cancer stem cell-like phenotype in breast cancer and allowing cells to develop endocrine therapy resistance. UC San Diego: School of Medicine. Retrieved from “https://escholarship.org/uc/item/5882d9j7”