Gastrointestinal Cancers

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Getting treated for gastrointestinal (GI) cancers at City of Hope puts your care in the hands of world experts in cancers affecting the digestive system. It means comprehensive, multidisciplinary care from a team offering the newest, leading-edge treatments for both early- and late-stage disease, including robotic and minimally invasive surgery and precision medicine.

As a leader in the diagnosis, treatment and research of GI cancers, City of Hope’s Gastrointestinal Cancer Program takes a multidisciplinary approach to your care for:

Our team works together to ensure you get the best treatments, and the best outcomes, using:

  • Minimally invasive, robotically assisted surgical techniques to remove tumors with less discomfort, reduced risk of complications and shorter recovery times
  • Highly precise radiation therapy to treat tumors with minimal exposure to surrounding normal tissue
  • Targeted drugs and drug combinations that treat advanced cancers with greater effectiveness and fewer side effects compared to traditional chemotherapy
  • A wide range of clinical trials, giving patients access to the newest cancer treatments and tests not readily available elsewhere
  • Supportive care services to help patients and their loved ones with wellness and palliative care issues that may arise during, and after, cancer treatment

Internationally recognized

As one of a handful of institutes to be given the elite designation of comprehensive cancer center by the National Cancer Institute, City of Hope is a leader in the research and treatment of gastrointestinal cancers. We are internationally recognized for research and breakthrough treatment, and have been named one of America's top cancer hospitals by U.S. News & World Report for over a decade.


City of Hope’s approach to treating gastrointestinal cancers starts with a coordinated, multidisciplinary care team whose main goals are helping you live a long, healthy, cancer-free life. We combine leading-edge technologies — like minimally invasive, laparoscopic and robotic surgery — with the latest therapeutic and radiological advances.

We are one of only a few dozen centers in the country that treat gastrointestinal cancers using a comprehensive approach — by a team whose sole focus is treating these types of cancer. Your care includes regular interaction and input from a team that includes surgeons, oncologists, gastroenterologists, radiologists and pathologists — along with nurses, social workers, nutritionists and specially trained support staff.

Learn more about symptoms, diagnosis, risk factors and treatment options of specific gastrointestinal cancers:

City of Hope’s world renowned physicians and researchers use the latest in technology and innovation to treat cancer — coupled with an enduring belief in providing compassionate care. If you have been diagnosed with gastrointestinal cancer, or are looking for a second opinion about your treatment, request an appointment online or contact us at 800-826-HOPE. Please visit Making Your First Appointment for more information.

Colon and Rectal Surgery

Stephen M. Sentovich, M.D., M.B.A.

Clinical Specialties

  • Colon and Rectal Surgery

Diagnostic Radiology

Jonathan Kessler, M.D.

Clinical Specialties

  • Diagnostic Radiology
  • Interventional Radiology


Trilokesh Kidambi, M.D.

Clinical Specialties

  • Gastroenterology
James L. Lin, M.D.

Clinical Specialties

  • Gastroenterology

Medical Oncology

Joseph Chao, M.D.

Clinical Specialties

  • Medical Oncology
Vincent Chung, M.D.

Clinical Specialties

  • Medical Oncology
Marwan G. Fakih, M.D.

Clinical Specialties

  • Medical Oncology
Lucille A Leong, M.D.

Clinical Specialties

  • Medical Oncology
  • Hematology
Dean W. Lim, M.D.

Clinical Specialties

  • Medical Oncology

Radiation Oncology

Yi-Jen Chen, M.D., Ph.D.

Clinical Specialties

  • Radiation Oncology

Surgical Oncology

Laleh Melstrom, M.D., M.S.

Clinical Specialties

  • Surgical Oncology
  • Liver Cancer and Metastases
  • Pancreas Cancer
  • Gallbladder Cancer and Bile Duct Cancer
  • Robotic Minimally Invasive Surgery
Mustafa Raoof, M.D.

Clinical Specialties

  • Surgical Oncology
Vijay Trisal, M.D., F.A.C.S.

Clinical Specialties

  • Surgical Oncology
Yanghee Woo, M.D.

Clinical Specialties

  • Surgical Oncology
  • Robotic Surgery
  • Minimally Invasive Surgery

Urologic Oncology

Kevin G. Chan, M.D.

Clinical Specialties

  • Urologic Oncology
  • Urology


Clinical trials – research studies that involve volunteer patients – are a crucial component to developing new, more effective treatments that save lives. Many of today’s standard therapies are based on the results of previous trials, some of which were initiated at City of Hope.

Getting treated for gastrointestinal cancers at City of Hope means you are steps away from labs where new treatments for cancer are being developed every day. That proximity means you benefit from something unique in cancer care — bench to bedside treatment.

“Bench to bedside” means innovative research we are conducting in our labs is moved quickly to the bedside to treat our patients. We offer drug, surgical and other clinical trials aimed at improving survival rates and enhancing quality of life.

Browse  through some of our clinical trials and research projects.

Living with a gastrointestinal cancer

When you come to City of Hope, you have access to a strong network of support services and staff to help you and your family along your cancer journey. That support includes everything from talk therapy to meditation to being paired up with a patient navigator — and includes help with:

Learn more about these resources at our Living with Cancer or Supportive Care Medicine sites.

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