Hua Yu, Ph.D.

626-256-4673, ext. 63365
Hua Yu, Ph.D.
Billy and Audrey L. Wilder Professor in Tumor Immunotherapy, Department of Immuno-Oncology, Co-leader, Cancer Immunotherapeutics Program, Comprehensive Cancer Center
Research Area
  • Role of Stat3 in Cancer Progression, Immunosuppression and Therapy Resistance
  • Development of Innovative Delivery Platforms to Target the Undruggables Including STAT3
Research Teams
Immuno-Oncology

Dr. Hua Yu Lab has made groundbreaking contributions to understanding the role of STAT3 in cancer. The lab was the first to demonstrate STAT3 as a therapeutic target in vivo. Additionally, the lab pioneered research on STAT3’s critical role in promoting immunosuppression within the tumor microenvironment. Dr. Yu’s research also identified STAT3 as a key regulator of tumor angiogenesis and metastasis.

Hua Yu Lab

Location

Education & Experience

Degrees

  • 1988, Columbia University, New York, NY., Ph.D., Molecular Biology

  • 1983, Columbia University, New York, NY., B.A., Biology

Fellowship

  • 1989 - 1992, University of Michigan, Ann Arbor, MI, Postdoc, Molecular Biology

Professional Experience

  • 2013 - present, Billy and Audrey L. Wilder Professor in Tumor Immunotherapy

  • 2011 - present, Co-leader, Cancer Immunotherapeutics Program, Comprehensive Cancer Center, City of Hope, Duarte, CA

  • 2005 - present, Professor and Associate Chair, Department of Cancer Immunotherapeutics & Tumor Immunology, Beckman Research Institute of City of Hope, Duarte, CA

  • 2002 - 2005, Associate Professor, Immunology Program, Moffitt Cancer Center, Tampa, FL

  • 1995 - 2002, Assistant Professor, Immunology Program, Moffitt Cancer Center, Tampa, FL

  • 1994 - 1995, Research Scientist, Department of Microbiology and Immunology, University of Michigan, Ann Arbor, MI

Research

Laboratory

Our research focuses on understanding the role of STAT3 signaling and other oncogenic pathways in cancer therapeutic resistance, immunosuppression, and metastasis in diverse cancer types.  The lab has developed several innovative delivery technologies to target undruggable intracellular targets.

Hua Yu Lab