Hossein Mehdikhani, M.D.

877-541-4673
Hossein Mehdikhani, M.D.
Diagnostic Radiologist
Clinical Expertise

Nuclear Medicine

Other Languages Spoken
Persian
Academic Appointments

Assistant Clinical Professor, Department of Diagnostic Radiology

Clinical Teams
Diagnostic Radiology

Hossein Mehdikhani, M.D., is dual-boarded in diagnostic radiology and nuclear medicine. From an early age, Hossein Mehdikhani, M.D., was drawn to science and problem-solving, but what truly inspired him was the human aspect of medicine — being able to make a real difference in someone’s life. Becoming a physician allowed him to combine science, empathy, and service. Dr. Mehdikhani's fascination with Radiology and Nuclear Radiology stems from the advanced technology and diagnostic precision these fields offer. He was captivated by the ability to visualize physiological processes and guide treatment using molecular imaging, which felt like a field where he could contribute meaningfully to both diagnosis and therapy.

Dr. Mehdikhani earned his medical degree at Tehran University of Medical Sciences (TUMS) and completed his Nuclear Medicine Residency at Icahn School of Medicine at Mount Sinai, followed by a Radiology Residency at Columbia University Medical Center-Harlem Hospital. His research fellowship at Duke University Medical Center further solidified his decision to focus on oncology, particularly in cancer detection, staging, and therapy.

Dr. Mehdikhani is deeply committed to community service and has collaborated on research projects in the fields of stem cells and cardiology in Iran. He is passionate about expanding access to advanced cancer care and is excited about theranostics — specifically targeted radioligand therapy using agents like Lutetium-177. His dedication to patient care and innovative research makes him a compassionate and highly skilled radiologist. Dr. Mehdikhani speaks Persian fluently.

Location

Education & Experience

Board Certifications

  • American Board of Radiology
  • American Board of Nuclear Medicine

Degrees

  • 2005, Doctor of Medicine, Tehran University of Medical Sciences, Tehran, Iran

Residencies

  • 2018–2022, Resident of Radiology (Chief Resident), Columbia University Medical Center-Harlem Hospital Center, New York, New York
  • 2015–2018, Resident of Nuclear Medicine, Mount Sinai Health System, New York, New York
  • 2014–2015, Preliminary Surgery Resident, University of Oklahoma College of Medicine, Tulsa, Oklahoma

Professional Experience

  • 2025–present, Assistant Clinical Professor, Department of Diagnostic Radiology, City of Hope Orange County, Irvine, California
  • 2022–2025, Assistant Clinical Professor, Department of Diagnostic Radiology, University of New Mexico, Albuquerque, New Mexico

Publications

  • Hossein Mehdikhani, Maria Habib, Somali Gavane, Jad Bou Ayache, Brett Miles, Peter Som, and Lale Kostakoglu. PET-MRI provides incremental value in patients with head and neck cancer. Journal of Nuclear Medicine 59, no. supplement 1 (2018): 635.
  • Heiba, Sherif, Somali Gavane, Abbas Tuli, Hossein Mehdikhani, Yasir Ahmad, Karin Knesaurek, Edward Kim, and Lale Kostakoglu. Accuracy of Prediction for Y-90 Glass Microsphere Radioembolization in Hepatocellular Carcinoma Using IntrahepaticTc-99m MAA planning SPECT/CT. Journal of Nuclear Medicine 59, no. supplement 1 (2018): 1377.
  • Hossein Mehdikhani MD, Joshua Brody MD, Morton Coleman MD, Jad Bou Ayache MD, Yasir Ahmad MD, Kanungnij Thamnirat MD and Lale Kostakoglu MD. Comparative assessment of baseline and interim PET metabolic tumor volumes with respect to survival in Hodgkin Lymphoma using two image analysis softwares. Abstracts for the Society of Nuclear Medicine and Molecular Imaging, Greater New York and New England Chapters, 31st Annual Northeast Regional Scientific Meeting, Mystic CT, November 3–5, 2017, Clinical Nuclear Medicine: April 2018 - Volume 43 - Issue 4 - p 299-303.
  • Hossein Mehdikhani MD, kanungnij Thamnirat MD, Morton Coleman MD, Joshua Brody MD, Lale Kostakoglu MD. Interim PET metabolic tumor volume is predictive of progression free survival in hodgkin lymphoma. American College of Nuclear Medicine (ACNM), 2018 ACNM Annual Meeting and SNMMI Mid-Winter Meeting, Resident and Fellow Abstracts. January 25–27, 2018 Orlando, FL
  • Sung, Anthony D., Syed Hassan, Diana M. Cardona, Daniel Wild, Krista Rowe Nichols, Hossein Mehdikhani, Bryan Balmadrid et al. "Late gastrointestinal complications of allogeneic hematopoietic stem cell transplantation in adults." Biology of Blood and Marrow Transplantation 24, no. 4 (2018): 734-740.
  • Heiba, Sherif, Somali Gavane, Abbas Tuli, Hossein Mehdikhani, Karin Knesaurek, and Lale Kostakoglu. Value of 99mTc-MAA SPECT/CT in Planning for 90Y-Labeled Glass Microsphere Radioembolization in Hepatocellular Carcinoma. Journal of Nuclear Medicine 58, no. supplement 1 (2017): 1040-1040.
  • Hossein Mehdikhani MD, Sherif Heiba MD, Lale Kostakoglu MD. Added Value of Hepatobiliary Scintigraphy SPECT-CT to Ultrasound and CT Scan for Detection of gallbladder anomalies in patients with clinically suspected acute cholecystitis. Clinical Nuclear Medicine. Aug 2017; 42(8), 651–653.
  • Hossein Mehdikhani and Sherif Heiba. Successful staging of synchronous gastric cancer and diffuse large b-cell lymphoma (DLBCL) using f-18-fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) based on distinctive levels of metabolic activity between the two malignancies. Indian Journal of Nuclear Medicine 32, no. 1 (2017): 85.
  • Hossein Mehdikhani MD, Sherif Heiba MD, Lale Kostakoglu MD. Case Report: Early detection of pelvic fractures with SPECT-CT. Clinical Nuclear Medicine: September 2016, Volume 41, Issue 9, p 749–750.
  • Daniel Wild, Anthony D. Sung, Diana Cardona, Constance Cirricione, Keith Sullivan, Claire Detweiler, Michael Shealy, Bryan Balmadrid, Krista L. Rowes , Nelson Chao, Sadhna Piryani, Hossein Mehdikhani Karimabad, Paul Martin, Martin Poleski. The Diagnostic Yield of Site and Symptom-Based Biopsies for Acute Gastrointestinal Graft-Versus-Host Disease: A 5-Year Retrospective Review. Dig Dis Sci. Mar 2016; 61(3):806-13.
  • Anthony D. Sung MD Diana Cardona MD, Krista Rowe RN, MSN, AOCNS, Hossein Mehdikhani MD, Claire Detweiler MD, Michael Shealy MD, Daniel Wild MD, Martin Poleski MD, Constance
    Cirrincione MS, Zhiguo Li PhD, Nelson J. Chao MD, Keith Sullivan MD. Late Gastrointestinal Complications of Allogeneic Hematopoietic Stem Cell Transplantation. Biology of Blood and Marrow Transplantation, Feb 2015, Volume 21, Issue 2, Supplement Pages S314-S315.
  • Mehdikhani Karimabad H, Shabestari M, Baharvand H, Vosough A, Gourabi H, Shahverdi A, Shamsian A, Abdolhoseini S, Moazzami K, Marjanimehr MM, Emami F, Bidkhori HR, Hamedanchi A, Talebi S, Farrokhi F, Jabbari-Azad F, Fadavi M, Garivani U, Mahmoodi M, Aghdami N. Lack of beneficial effects of granulocyte colony-stimulating factor in patients with subacute myocardial infarction undergoing late revascularization: a double-blind, randomized, placebo-controlled clinical trial. Acta Cardiol. 2011 Apr; 66(2):219-24.