Lorinda A. Soma, M.D.

(877) 460-4673
Lorinda A. Soma, M.D.
Pathologist
Clinical Expertise
  • Hematopathology
Academic Appointments
  • Clinical Professor, Department of Pathology
Clinical Teams
Pathology

Lorinda Soma MD makes it her goal to provide the highest quality, comprehensive diagnostic care as quickly and economically as possible.  As a pathologist specializing in hematopoietic cancers, she collaborates with her colleagues utilizing a multidisciplinary approach to diagnosis and patient care.  Dr. Soma is a physician–teacher–scientist who has co-authored many peer-reviewed studies and book chapters.  She joined City of Hope in 2022, moving from the University Washington Medical Center in Seattle Washington where she was lab director and hematopathology service chief.  She is a longtime member the Society for Hematopathology (including time as chair of the education committee), United States and Canadian Academy of Pathology, the International Clinical Cytometry Society and the American Society for Clinical Pathology.

Location

Education & Experience

Degrees
  • 1998, Doctor of Medicine, University of Minnesota Medical Center, Minneapolis, MN 
  • 1994, Bachelor of Arts, Hamline University, St. Paul, MN 
Fellowship
  • 2005, Hematopathology, University of Pittsburgh Medical Center, Pittsburgh, PA
  • 2003, Surgical Pathology, Mayo Medical Center, Rochester, MN
Residency
  • 2002, Anatomic and Clinical Pathology, University of Pennsylvania Medical Center, Philadelphia, PA
Professional Experience
  • 2022-present, Clinical Professor, Division of Hematopathology, Department of Pathology, City of Hope, Duarte, CA
  • 2017-2022, Associate Professor and Hematopathologist, University of Washington, Laboratory Medicine & Pathology, Seattle, WA
  • 2012-2017, Assistant Professor and Hematopathologist, University of Washington, Laboratory Medicine & Pathology, Seattle, WA
     

Publications

  • Lee WY, Kim YS, Li A, Reid J, Davidson J, Hristov AC, Perry AM, Soma L, & Song JY (2025). Expanding the use of T cell receptor beta constant 1 immunohistochemistry in formalin-fixed paraffin-embedded tissues in assessing T cell clonality in mature and immature T cell neoplasms. Histopathology, 10.1111/his.15454. Advance online publication. https://doi.org/10.1111/his.15454
  • Hughes J, Soma L, Lee W and Song JY. Plasma cells show decreased CD138 expression when exposed to buffers containing sodium azide. Cytometry Part B - Clinical Cytometry. 2025: https://doi.org/10.1002/cyto.b.22221
  • Soma L, Crisan L, Reid J, Lee W, Song J, Afkhami M, Shouse G, Fei F, Danilova O, Pillai R, Zain J, Querfeld C. Epstein-Barr virus-positive, primary cutaneous marginal zone lymphoma, with transformation: Case report and review of the literature. Am J Clin Pathol. 2024 Sep 17: aqae124. doi: 10.1093/ajcp/aqae124. Epub ahead of print. PMID: 39290045.
  • Portuguese A, Fang M, Tuazon S, Pont M, Qu X, Shasha C, Comstock M, Lyons J, Cole G, Newell E, Glynn E, Soma L, Green D. Acquired CD38 gene deletion as a mechanism of tumor antigen escape in multiple myeloma. Blood Adv. 2023 Dec 12;7(23):7235-7238. PMID: 37844282. In Press
  • Zarling L, Stevenson P, Soma L, Martino C, Percival M, Halpern A, Ghiuzeli C, Becker P, Oehler V, Cooper J, Orozco J, Hendrie P, Walter R, Estey E, Cassaday R. Hyper-CVAD versus dose-adjusted EPOCH as initial treatment for adults with acute lymphoblastic leukemia. Eur J Haematol. 2023 Dec;111(6):863-871. PMID: 37670560.
  • Boyer DF, Perry A, Wey E, Hsueh J, Li A, Jackson R, Soma L, Zhang W, Song J. Fibrin-associated large B-cell lymphoma shows frequent mutations related to immune surveillance and PTEN. Blood. 2023 Sep 14;142(11):1022-1025. PMID: 37433264.
  • Zamò A, van den Brand M, Climent F, de Leval L, Dirnhofer S, Leoncini L, Ng SB, Ondrejka SL, Quintanilla-Martinez L, Soma L, Wotherspoon A. Correction to: The many faces of nodal and splenic marginal zone lymphomas. A report of the 2022 EA4HP/SH lymphoma workshop. Virchows Arch. 2023 Sep;483(3):437. PMID: 37695411.
  • Climent F, Nicolae A, de Leval L, Dirnhofer S, Leoncini L, Ondrejka SL, Soma L, Wotherspoon A, Zamò A, Quintanilla-Martinez L, Ng SB. Cytotoxic peripheral T-cell lymphomas and EBV-positive T/NK-cell lymphoproliferative diseases: emerging concepts, recent advances, and the putative role of clonal hematopoiesis. Virchows Arch. 2023, Sep;483(3):333-348. PMID: 37646869.
  • Di Napoli A, Soma L, Quintanilla-Martinez L, de Leval L, Leoncini L, Zamò A, Ng SB, Ondrejka SL, Climent F, Wotherspoon A, Dirnhofer S. Correction to: Cavity-based lymphomas: challenges and novel concepts. A report of the 2022 EA4HP/SH lymphoma workshop. Virchows Arch. 2023 Sep;483(3):435. PMID: 37747560
  • Quintanilla-Martinez L, Laurent C, Soma L, Ng SB, Climent F, Ondrejka SL, Zamò A, Wotherspoon A, de Leval L, Dirnhofer S, Leoncini L. Emerging entities: high-grade/large B-cell lymphoma with 11q aberration, large B-cell lymphoma with IRF4 rearrangement, and new molecular subgroups in large B-cell lymphomas. Virchows Arch. 2023 Sep;483(3):281-298. PMID: 37555980.