An NCI-designated Comprehensive Cancer Center

Liver Cancer

“Here [at City of Hope], there is one mission: It is treatment of cancer patients to make them no longer cancer patients but recovering individuals that are going back to their families.”
Yuman Fong, M.D., chair, Department of Surgery

An estimated 42,220 adults (30,610 men and 11,610 women) in the United States will be diagnosed with primary liver cancer in 2018.

Liver cancer care at City of Hope means you will get the most advanced, leading-edge treatments available, including minimally invasive robotic surgery, novel cancer-fighting drugs and highly precise radiation delivery. Our multidisciplinary team of specialized experts - many of whom are leaders and innovators in the field of liver cancer treatment and research - are solely focused on giving you the greatest chance at a lasting cure.

We will answer your questions, calm your concerns and design a personalized treatment plan to give you the best possible outcome.

Request a consultation

If you have been diagnosed with liver cancer, are at a high risk for developing liver cancer or are looking for a second opinion consultation about your treatment, you may request an appointment online or contact us at 800-826-4673. Please visit Making Your First Appointment for more information. 

Our Expertise

City of Hope, located in Southern California, has been named a best hospital for cancer by U.S. News & World Report for over a decade and a National Cancer Institute comprehensive cancer center, the highest designation that recognizes our commitment to cancer treatment, research and education. As a founding member of the National Comprehensive Cancer Network, our doctors also help develop and improve evidence-based liver cancer treatment guidelines for patients throughout the country.

Highlights of our liver cancer program include:

  • A patient-centered treatment approach guided by your unique needs and background, including molecular and genetic testing of your cancer to find the most effective therapies
  • Our leadership, innovation and experience in minimally invasive and complex surgeries for liver cancer — with one of the best track records for safety and long-term outcomes
  • Advanced technology and expertise minimally invasive, robotically assisted surgeries that can reduce discomfort, blood loss and recovery times for liver cancer patients, with some being able to go home within 24 hours after the operation
  • Needle- and catheter-based therapies, such as ablation and radioembolization, that can treat liver tumors effectively without major incisions
  • Experience in hepatic arterial infusion (HAI), which delivers cancer-fighting drugs directly to the tumor site for greater effectiveness
  • A wide portfolio of drugs that can fight cancer better with fewer side effects, including targeted therapy and immunotherapy that attacks liver cancer cells with greater accuracy
  • Targeted radiation therapy delivery that can focus on liver tumors while sparing healthy liver tissue, allowing the treatment to destroy the tumor completely or shrink it small enough for surgical removal
  • Access to a wide range of clinical trials that may be more effective against liver cancer and/or less harmful to the patient; many of these promising therapies are only available to City of Hope patients
  • Supportive care services to address a wide range of disease- and treatment-related concerns


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