Lior Goldberg, M.D., M.S.
- Pediatric Cancers
- Cellular Therapy/CAR T Cell
- Cellular Therapy
- Immune Cell Metabolism and Trafficking
- Assistant Professor, Department of Pediatrics
For Lior Goldberg, M.D., M.S., his work as pediatric oncologist centers around curiosity, compassion and courage. He makes sure to genuinely get to know the patients and families he serves, sharing in the difficult aspects of cancer and its treatment while helping ease distress. Ultimately, his goal is to do the right thing for the people who count on him for the best in cancer care.
Dr. Goldberg received his medical degree from Tel Aviv University, School of Medicine, and did his residency at Sheba Medical Center at Tel-Hashomer in Israel, where he was recognized for his clinical excellence, leadership and outstanding achievements. He went on to complete a clinical pediatric hematology-oncology fellowship at Children’s Hospital Los Angeles and an immunotherapy research fellowship at City of Hope under the mentorship of Stephen J. Forman, M.D.
Dr. Goldberg is the recipient of several awards, including the Children’s Hospital of Los Angeles Fellow Teaching Award for Outstanding Teaching and Commitment, the SHARE Inc. Research Fellow Award in Pediatric Hematology-Oncology and the Hyundai Hope On Wheels Young Investigator Award.
As a physician-scientist, Dr. Goldberg helps patients and families directly by overseeing treatment and on a broader scale through his work developing new therapies. He has authored more than a dozen peer-reviewed studies in areas such as gene therapy, cell therapy and precision medicine.
Location
Duarte Cancer Center
Duarte, CA 91010
Awards & Memberships
2024 NIH/National Cancer Institute K12 Award
2024 The Margaret E. Early Medical Research Trust Award
2023 The Schwartz Accelerator Fund Award
2023 Hyundai Hope On Wheels Young Investigator Award
2020 The Children’s Hospital Los Angeles Fellow Teaching Award for Outstanding Teaching and Commitment
2019 SHARE Inc Research Fellow Award in Pediatric Hematology-Oncology
The American Society of Hematology
Children's Oncology Group
American Association for Cancer Research
American Society of Pediatric Hematology/Oncology
The American Society of Transplantation and Cellular Therapy
Society for Immunotherapy of Cancer
Publications
- Goldberg, L., Haas, E. R., Urak, R., Vyas, V., Pathak, K. V., Garcia-Mansfield, K., Pirrotte, P., Singhal, J., Figarola, J. L., Aldoss, I., Forman, S. J., & Wang, X. (2024). Immunometabolic adaptation of CD19-targeted CAR T cells in the central nervous system microenvironment of patients promotes memory development. Cancer research. PMID: 38315779.
- Munoz, A. M., Urak, R., Taus, E., Hsieh, H. J., Awuah, D., Vyas, V., Lim, L., Jin, K., Lin, S. H., Priceman, S. J., Clark, M. C., Goldberg, L., Forman, S. J., & Wang, X. Dexamethasone Potentiates Chimeric Antigen Receptor T Cell Persistence and Function by Enhancing IL-7Rα Expression. Molecular therapy. December 2013. PMID: 38140726.
- Urak R, Gittins B, Soemardy C, Grepo N, Goldberg L, Maker M, Shevchenko G, Davis A, Li S, Scott T, Morris KV, Forman SJ, Wang X. Evaluation of the Elements of Short Hairpin RNAs in Developing shRNA-Containing CAR T Cells. Cancers (Basel). 2023 May. PMCID: PMC10216594
- Gupta D, Goldberg L, Dickinson A, Hughes M, Anand V, Stokke J, Corden M. An 8-Year-Old Boy with Prolonged Fever and Subcutaneous Nodules. Pediatrics. 2022 Apr. PMID: 35490281
- Goldberg L, Haas ER, Vyas V, Urak R, Forman SJ*, Wang X*. Single-cell analysis by mass cytometry reveals CD19 CAR T cell spatiotemporal plasticity in patients. Oncoimmunology. 2022 Jan. PMID: 35223193.
- Canetti M, Carmi A, Paret G, Goldberg L, Adler A, Amit S, Rokney A, Ron M, Grisaru-Soen G. Invasive Group A Streptococcus Infection in Children in Central Israel in 2012–2019. Pediatr Infect Dis J. 2021 Jul. PMID: 34097654.
- Truong T, Ryutov A, Pandey U, Yee, Goldberg L, Bhojwani D et al. Increased viral variants in children and young adults with impaired humoral immunity and persistent SARS-CoV-2 infection: A consecutive case series. EBioMedicine. 2021 May. PMID: 33915337.
- Goldberg L, Simon AJ, Lev A, Barel O, Kunik V, Stauber T, Somech R. Atypical Immune Phenotype in IL2RG and JAK3 SCID Patients with Novel Mutations. Genes & Immunity. 2020 Nov. PMID: 32921793.
- Bercovich O, Tirosh-Wagner T, Goldberg L, Vardi A, Mishali D, Paret G, Nevo-Caspi Y. Immunomodulatory miRNAs as Biomarkers for the Postoperative Course Following Surgery for the Repair of Congenital Heart Defects in Children. Congenital Heart Disease. 2020 Sep.
- Klivitsky A, Algabria S, Paret G, Michaan N, Goldberg L, Halutz O, Grisaru-Soen G. Impact of rotavirus vaccine on admissions due to acute gastroenteritis and rotavirus gastroenteritis in Israel. Acta Paediatr. 2020 Jul. PMID: 32654273
- Goldberg L, Simon AJ, Rechavi G, Lev A, Barel O, Kunik V, Toren A, Schiby G, Tamary H, Steinberg-Shemer O, Somech R. Congenital neutropenia with variable clinical presentation in novel mutation of SRP54 gene. Pediatric Blood & Cancer. 2020 Apr. PMID: 32277798.
- Goldberg L, Krauthammer A, Ashkenazi M, Soudack M, Tokatly Latzer I, Vardi A, Paret G. Predictors for plication performance following diaphragmatic paralysis in children. Pediatric Pulmonology. 2019 Oct. PMID: 31589009.
- Manor U, Lev A, Simon AJ, Hutt D, Toren A, Bielorai B, Goldberg L, Stauber T, Somech R. Immune reconstitution after HSCT in SCID-a cohort of conditioned and unconditioned patients. Immunol Res. 2019 Jun. PMID: 3122251.
- Tokatly Latzer I, Nahum E, Cavari Y, Lazar I, Ben-Ari Y, Ben-Shimol S, Ben-Shalom G, Geffen Y, Goldberg L, Rubinstein M, Keller N, Pessach IM, Paret G. Treatment Outcomes of Stenotrophomonas maltophilia Bacteremia in Critically Ill Children: A Multicenter Experience. Pediatr Crit Care Med. 2019 May. PMID: 31058792.
- Krauthammer A, Lahad A, Goldberg L, Sarouk I, Weiss B, Somech R, Soudack M, Pessach IM. Elevated IgM Levels as a Marker for a Unique Phenotype in Patients With Ataxia Telangiectasia. BMC Pediatrics. 2018 Jun. PMID: 29866155.
- Goldberg L, Tirosh-Wagner T, Vardi A, Abbas H, Pillar N, Shomron N, Nevo-Caspi Y, Paret G. Circulating MicroRNAs: A Potential Biomarker for Cardiac Damage, Inflammatory Response, and Left Ventricular Function Recovery in Pediatric Viral Myocarditis. J Cardiovasc Transl Res. 2018 Jun. PMID: 29916103.
- Goldberg L, Bar-Aluma BE, Krauthammer A, Efrati O, Sharabi Y. Ambulatory Blood Pressure Profiles in Familial Dysautonomia. Clin Auton Res. 2018 Feb. PMID: 29435868.
- Goldberg L, Abutbul-Amitai M, Paret G, Nevo-Caspi Y. Alternative Splicing of STAT3 Is Affected by RNA Editing. DNA Cell Biol. 2017 May. PMID: 2827838.