Carlesso Lab Publications

  • Toghani D, Gupte S, Zeng S, Mahammadov E, Crosse EI, Seyedhassantehrani N, Burns C, Gravano D, Radtke S, Kiem HP, Rodriguez S, Carlesso N, [et al. ] and Spencer JA, Silberstein L.: Niche-derived Semaphorin 4A safeguards functional identity of myeloid-biased hematopoietic stem cells. Nat Aging. 2025 Feb 20. doi: 10.1038/s43587-025-00837-x. Epub ahead of print.: Nat Aging. 2025 Jan 29. doi: 10.1038/s43587-024-00798-7. PMID: 39979638.
  • Ojeda AV, Awabdeh D, Brewster B, Rockne R, O'Meally D, Yin HH, Carlesso N, Brown CE, Gutova M, Barish ME. Modeling cerebral development in vitro with L-MYC-immortalized human neural stem cell-derived organoids. bioRxiv [Preprint]. 2025 Feb 13:2025.02.12.637976. doi: 10.1101/2025.02.12.637976. PMID: 39990325; PMCID: PMC11844543. In revision in Cell Report.
  • Martella M, Carlesso N, Waller ZAE, Marcucci G, Pichiorri F, Smith SS. Genomic Frequencies of Dynamic DNA Sequences and Mammalian Lifespan. Cancer Genomics Proteomics. 2024 May-Jun;21(3):238-251. doi: 10.21873/cgp.20443. PMID: 38670588; PMCID: PMC11059594.
  • Kim YW, Zara G, Kang H, Branciamore S, O'Meally D, Feng Y, Kuan CY, Luo Y, Nelson MS, Brummer AB, Rockne R, Chen ZB, Zheng Y, Cardoso AA, Carlesso N. Integration of single-cell transcriptomes and biological function reveals distinct behavioral patterns in bone marrow endothelium. Nat Commun. 2022 Nov 24;13(1):7235. PMID: 36433940. PMCID:PMC9700769.
  • Carlesso N. Targeting the bone marrow niche in hemoglobinopathies. Blood. 2020 Jul 30;136(5):529-531. doi: 10.1182/blood.2020006305.Blood. 2020. PMID: 32730580 No abstract available.
  • Rockne RC, Branciamore S, Qi J, Frankhouser DE, O'Meally D, Hua WK, Cook G, Carnahan E, Zhang L, Marom A, Wu H, Maestrini D, Wu X, Yuan YC, Liu Z, Wang LD, Forman S, Carlesso N, Kuo YH, Marcucci G. State-Transition Analysis of Time-Sequential Gene Expression Identifies Critical Points That Predict Development of Acute Myeloid Leukemia.  Cancer Res. 2020 Aug 1;80(15):3157-3169. doi: 10.1158/0008-5472.CAN-20-0354. Epub 2020 May 15. Cancer Res. 2020. PMID: 32414754 Free PMC article.
  • Rodriguez S., Abundis C, Boccalatte F, Mehrotra P, Chiang MY, Yui MA, Wang L, Zhang H, Zollman A, Bonfim-Silva R, Kloetgen A, Palmer J, Sandusky G, Wunderlich M, Kaplan MH, Mulloy JC, Marcucci G, Aifantis I, Cardoso AA, Carlesso N. Therapeutic targeting of the E3 ubiquitin ligase SKP2 in T-ALL. Leukemia. 2020 May;34(5):1241-1252. doi: 10.1038/s41375-019-0653-z. Epub 2019 Nov 26. Leukemia. 2020. PMID: 31772299 Free PMC article.
  • Wang L, Kamocka MM, Zollman A, Carlesso N. Combining Intravital Fluorescent Microscopy (IVFM) with Genetic Models to Study Engraftment Dynamics of Hematopoietic Cells to Bone Marrow Niches. Journal of visualized experiments: JoVE. 2017(121). Epub 2017/04/01. doi: 10.3791/54253. PubMed PMID: 28362378; PMCID: PMC5407599.
  • Zhang H, Rodriguez S, Wang L, Wang S, Serezani H, Kapur R, Cardoso AA, Carlesso N. Sepsis Induces Hematopoietic Stem Cell Exhaustion and Myelosuppression through Distinct Contributions of TRIF and MYD88. Stem Cell Reports. 2016;6(6):940-56. Epub 2016/06/07. doi: 10.1016/j.stemcr.2016.05.002. PubMed PMID: 27264973; PMCID: PMC4911503. (23*citations)
  • Bi P, Shan T, Liu W, Yue F, Yang X, Liang XR, Wang J, Li J, Carlesso N, Liu X, Kuang S. Inhibition of Notch signaling promotes browning of white adipose tissue and ameliorates obesity. Nature Medicine. 2015;20(8):941305. Epub 2014/07/21. doi: 10.1038/nm.3615. PubMed PMID: 25038826; PMCID: PMC4181850. (105*citations)
  • Wang L, Zhang H, Rodriguez S, Cao L, Parish J, Mumaw C, Zollman A, Kamoka MM, Mu J, Chen DZ, Srour EF, Chitteti BR, HogenEsch H, Tu X, Bellido TM, Boswell HS, Manshouri T, Verstovsek S, Yoder MC, Kapur R, Cardoso AA, Carlesso N. Notch-dependent repression of miR-155 in the bone marrow niche regulates hematopoiesis in an NF-kappaB-dependent manner. Cell Stem Cell. 2014;15(1):51-65. Epub 2014/07/06. doi: 10.1016/j.stem.2014.04.021. PubMed PMID: 24996169; PMCID: PMC4398997. (94*citations)

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