ENDING CANCER STARTS WITH HOPE

When cancer shows up, our 2,000 cancer experts show up stronger.

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Advancing Cancer Care Through Expertise, Innovation and Scale

City of Hope^® is among the nation's leading cancer research and treatment organizations, delivering breakthrough treatments, survival outcomes that exceed national benchmarks, access to more than 700 clinical trials and a network of 2,000+ cancer experts focused on ending cancer.

For more than a century, City of Hope has transformed groundbreaking discoveries into lifesaving treatments. Today, patients across the country have access to specialized cancer expertise, leading-edge therapies and compassionate care designed around every stage of the cancer journey. Learn about our cancer centers by exploring the links below.

City of Hope was recognized as one of the nation’s top hospitals for cancer care, according to U.S. News & World Report’s 2025-26 rankings.

Our Cancer Centers

Atlanta Area

City of Hope Chicago

Chicago Area

Los Angeles Area

NCI-Designated Comprehensive Cancer Center

Orange County Area

City of Hope Phoenix Cancer Center building

Arizona Area

NCI's Top Designation for Cancer Centers

Our National Cancer Center near Los Angeles is a National Cancer Institute (NCI)-Designated Comprehensive Cancer Center. This designation recognizes City of Hope as a national leader in cancer care and an institute dedicated to transforming research into new, innovative treatments for cancer patients across the country and world.

NCI Designated Comprehensive Cancer Graphic

Patient-Focused Care

Our reputation for groundbreaking discoveries, innovative treatments and compassionate care make us a leader in the fight to help patients here and around the world conquer cancer, diabetes, HIV/AIDS and other life-threatening diseases.

Cancers and Conditions

Refer a Patient to City of Hope

Forward-Focused Research

Our infrastructure and collaborative energy sets us apart. By having scientists, treatment staff and manufacturing facilities side-by-side, our treatment advances can travel from laboratory to patient with lifesaving speed.

City of Hope scientist conducting research

Explore Our Research

Search Clinical Trials

Read Latest News

Hope-Inspired Learning

As a leading research institute, our academic programs look beyond the standard treatments of today, providing educational opportunities that explore the latest advancements in research and therapies.

Graduation ceremony at the Beckman Research Institute

Explore Academics & Training

Irell & Manella Graduate School

FIND A CITY OF HOPE DOCTOR

City of Hope is home to many of the nation's leading cancer doctors. Find the right one for your patient’s needs.

FIND A CITY OF HOPE LOCATION

Headquartered in Duarte, California, with locations across the United States, our unique approach to care is available in your community.

HOW TO REFER A PATIENT

We're here to help and welcome the opportunity to partner with you in providing your patients with the latest treatment innovations.

PHYSICIAN CAREERS

Join a world leader in treating, researching and preventing life-threatening diseases, including cancer, diabetes and HIV/AIDS.

Hope Matters

More blog articles

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Why Don't More People Get Screened for Lung Cancer?

Lung cancer screening rates are very low in the U.S., with only 18% of eligible patients getting screened. Find out what may be behind the numbers.

image of a male doctor explaining something to a man

Is Blood in the Urine a Sign of Cancer?

Blood in urine may an early sign of several cancers, but it may also be caused by non-cancerous conditions. Learn how to differentiate and what to do if you see it.

image of a female doctor explaining a chart to a woman

7 Important Considerations When Choosing a Breast Cancer Center

Researching cancer centers will help you find the one in which you have the confidence you’re getting the best care for your breast cancer.

News and Stories of Hope

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Zoom wedding after diagnosis

Getting Back on Track: Young Stage 4 Lymphoma Survivor Looks to the Future

Jeff Henry, 34, was weeks away from his wedding when he was diagnosed with Stage 4 diffuse large B-cell lymphoma.

Stories of Hope

Patient Stories

City of Hope Earns Its Second Magnet® Recognition Across Southern California Locations

OC Hospital Building Exterior

City of Hope Orange County

2025: The Year the Next Chapter of Hope Began at City of Hope Orange County

2025 was a landmark year for City of Hope Orange County as it fulfilled its promise to the people of Orange County, bringing more advanced cancer treatment and pioneering research to the people who need it.

Give Hope

You can accelerate leading-edge research and help provide compassionate patient-care.