City of Hope®, one of the largest and most advanced cancer research and treatment organizations in the United States, with a 100+ year legacy, was recognized as one of the nation’s top hospitals for cancer care, according to U.S. News & World Report’s 2025-26 rankings. 

We bring breakthroughs from the laboratory to our patients with lifesaving speed – treating cancer with leading-edge technologies, innovative treatments and expert care personalized to each patient’s needs. 

And we treat patients across the United States through our national footprint of cancer centers. Learn about our cancer centers by exploring the links below.

Our Cancer Centers

NCI's Top Designation for Cancer Centers

Our National Cancer Center near Los Angeles is a National Cancer Institute (NCI)-Designated Comprehensive Cancer Center. This designation recognizes City of Hope as a national leader in cancer care and an institute dedicated to transforming research into new, innovative treatments for cancer patients across the country and world.

NCI Designated Comprehensive Cancer Graphic

Patient-Focused Care

Our reputation for groundbreaking discoveries, innovative treatments and compassionate care make us a leader in the fight to help patients here and around the world conquer cancer, diabetes, HIV/AIDS and other life-threatening diseases.

A group of City of Hope doctors providing patient care together
Cancers and Conditions We Treat
Find a Doctor
Refer a Patient to City of Hope

Forward-Focused Research

Our infrastructure and collaborative energy sets us apart. By having scientists, treatment staff and manufacturing facilities side-by-side, our treatment advances can travel from laboratory to patient with lifesaving speed.

A technician working in a lab
Explore Our Research
Search Clinical Trials
Read Latest News

Hope-Inspired Learning

As a leading research institute, our academic programs look beyond the standard treatments of today, providing educational opportunities that explore the latest advancements in research and therapies.

Graduation ceremony at the Beckman Research Institute
Explore Academics & Training
Irell & Manella Graduate School
Virtual Tours

Physician Resources

We provide referring physicians easy access to all pertinent information and needed resources.
FIND A CITY OF HOPE DOCTOR

City of Hope is home to many of the nation's leading cancer doctors. Find the right one for your patient’s needs.

Find a Doctor
FIND A CITY OF HOPE LOCATION

Headquartered in Duarte, California, with locations across the United States, our unique approach to care is available in your community.

Find a Location
HOW TO REFER A PATIENT

We're here to help and welcome the opportunity to partner with you in providing your patients with the latest treatment innovations.

Learn More
PHYSICIAN CAREERS

Join a world leader in treating, researching and preventing life-threatening diseases, including cancer, diabetes and HIV/AIDS.

Join Us

Hope Matters

More blog articles

No articles found matching the selected criteria.

News and Stories of Hope

See All
City of Hope Orange County Multi Faith Spiritual Care Center
Aug 21, 2025
Kelsey Dalton
City of Hope Orange County Unveils the First Multi-Faith Spiritual Care Center Designed to Immerse Cancer Patients in their Healing Places
Press Release
City of Hope Orange County Cancer Specialty Hospital
Aug 15, 2025
City of Hope Orange County
For patients with blood cancer, a promise fulfilled
City of Hope Orange County’s cancer specialty hospital will deliver lifesaving hematologic treatments and discoveries.
Orange County
Patient Care
image of a doctor speaking with a young woman
Aug 15, 2025
City of Hope
Why Are Younger Women in the Midwest Facing Higher Cancer Rates?
Cancer rates are growing among younger women, and the trend is particularly prevalent in the Midwest. Discover why screening is essential to early detection.
Patient Care
Chicago

Give Hope

You can accelerate leading-edge research and help provide compassionate patient-care.