Vu Nguyen Ngo Lab
Research Lab Overview
Vu Nguyen Ngo completed his Ph.D. degree in the laboratory of Jason Cyster at the University of California San Francisco, where he studied the molecular basis of lymphoid tissue organization by investigating the interactions between lymphocytes and stromal cells as well as the chemokines and cytokines they secret. He then joined the laboratory of Louis Staudt at the National Cancer Institute for postdoctoral training, where he developed an expertise in large-scale functional genomics research, using RNA interference technology to identify critical signaling pathways that harbor oncogenic mutations driving lymphomagenesis.
In 2010, Dr. Ngo was recruited to start his independent laboratory in the Division of Stem Cell and Leukemia Research at Beckman Research Institute of City of Hope. His laboratory has discovered an important role for recurrent mutations of cyclin D1, which results in deregulated protein turnover and therapy resistance in mantle cell lymphoma.
In 2017, Dr. Ngo joined the Department of Systems Biology where he uses innovative functional genomics tools and powerful animal modeling using relevant patient-derived lymphoma samples to gain new insights into critical signaling pathways that are important in lymphomagenesis and resistance to therapy.
Dr. Ngo is an award recipient of the American Society of Hematology Scholar Award, the Gabrielle’s Angel Foundation for Cancer Research, the Department of Defense’s Career Development, the Concern Foundation for Cancer Research, and NIH Research Grant Awards.
An associate professor in the Department of Systems Biology, Vu Nguyen Ngo, Ph.D.'s research focuses on molecular pathogenesis of lymphoid malignancies.
Lab Members
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Partnerships
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Our Publications
Mohanty A, Sandoval N, Phan A, Nguyen TV, Chen RW, Budde E, Mei M, Popplewell L, Pham LV, Kwak LW, Weisenburger DD, Rosen ST, Chan WC, Müschen M, Ngo VN
Mohanty S, Mohanty A, Sandoval N, Tran T, Bedell V, Wu J, Scuto A, Weisenburger D, Ngo VN
Mohanty A, Sandoval N, Das M, Pillai R, Chen L, Chen RW, Amin HM, Wang M, Marcucci G, Weisenburger DD, Rosen ST, Pham LV, Ngo V
Ngo VN
Lamy L, Ngo VN, Emre TNC, Shaffer AL, Yang Y, Tian E, Shaughnessy JD, Nair V, Kruhlak MJ, Zingone A, Landgren O, Staudt LM
Contact Information
34.1293409, -117.971358
Duarte, CA 91010