Recent Publications

 
  1. Aslamy, A., Oh, E., Olson, E.M., Zhang, J., Ahn, M., Moin, A.S.M., Tunduguru, R., Salunkhe, V.A., Veluthakal, R., & Thurmond, D.C. (2018). Doc2b Protects beta-Cells Against Inflammatory Damage and Enhances Function. Diabetes, 67(7), 1332-44. https://doi.org/10.2337/db17-1352
  2. Chan, W.K., Kang, S., Youssef, Y., Glankler, E.N., Barrett, E.R., Carter, A.M., Ahmed, E.H., Prasad, A., Chen, L., Zhang, J., Benson, D.M., Jr., Caligiuri, M.A., & Yu, J. (2018). A CS1-NKG2D Bispecific Antibody Collectively Activates Cytolytic Immune Cells against Multiple Myeloma. Cancer Immunol Res, 6(7), 776-87. https://doi.org/10.1158/2326-6066.CIR-17-0649
  3. Krishnan, A., Kapoor, P., Palmer, J.M., Tsai, N.C., Kumar, S., Lonial, S., Htut, M., Karanes, C., Nathwani, N., Rosenzweig, M., Sahebi, F., Somlo, G., Duarte, L., Sanchez, J.F., Auclair, D., Forman, S.J., & Berdeja, J.G. (2018). Phase I/II trial of the oral regimen ixazomib, pomalidomide, and dexamethasone in relapsed/refractory multiple myeloma. Leukemia, 32(7), 1567-74. https://doi.org/10.1038/s41375-018-0038-8
  4. Pal, S.K., Rosenberg, J.E., Hoffman-Censits, J.H., Berger, R., Quinn, D.I., Galsky, M.D., Wolf, J., Dittrich, C., Keam, B., Delord, J.P., Schellens, J.H.M., Gravis, G., Medioni, J., Maroto, P., Sriuranpong, V., Charoentum, C., Burris, H.A., Grunwald, V., Petrylak, D., Vaishampayan, U., Gez, E., De Giorgi, U., Lee, J.L., Voortman, J., Gupta, S., Sharma, S., Mortazavi, A., Vaughn, D.J., Isaacs, R., Parker, K., Chen, X., Yu, K., Porter, D., Graus Porta, D., & Bajorin, D.F. (2018). Efficacy of BGJ398, a Fibroblast Growth Factor Receptor 1-3 Inhibitor, in Patients with Previously Treated Advanced Urothelial Carcinoma with FGFR3 Alterations. Cancer Discov, 8(7), 812-21. https://doi.org/10.1158/2159-8290.cd-18-0229
  5. Armenian, S.H., Rinderknecht, D., Au, K., Lindenfeld, L., Mills, G., Siyahian, A., Herrera, C., Wilson, K., Venkataraman, K., Mascarenhas, K., Tavallali, P., Razavi, M., Pahlevan, N., Detterich, J., Bhatia, S., & Gharib, M. (2018). Accuracy of a Novel Handheld Wireless Platform for Detection of Cardiac Dysfunction in Anthracycline-Exposed Survivors of Childhood Cancer. Clinical Cancer Research, 24(13), 3119-25. https://doi.org/10.1158/1078-0432.ccr-17-3599
  6. Wong, J.Y.C., Filippi, A.R., Dabaja, B.S., Yahalom, J., & Specht, L. (2018). Total Body Irradiation: Guidelines from the International Lymphoma Radiation Oncology Group (ILROG). International Journal of Radiation Oncology Biology Physics, 101(3), 521-9. https://doi.org/10.1016/j.ijrobp.2018.04.071
  7. Gu, L., Lingeman, R.G., Yakushijin, F., Sun, E., Cui, Q., Chao, J., Hu, W., Li, H., Hickey, R.J., Stark, J.M., Yuan, Y.C., Chen, Y., Vonderfecht, S.L., Synold, T.W., Shi, Y., Reckamp, K.L., Horne, D., & Malkas, L.H. (2018). The anti-cancer activity of a first-in-class small molecule targeting PCNA. Clinical Cancer Research, Epub ahead of print. https://doi.org/10.1158/1078-0432.ccr-18-0592
  8. Yoon, S., & Rossi, J.J. (2018). Aptamers: Uptake mechanisms and intracellular applications. Advanced Drug Delivery Reviews, Epub ahead of print. https://doi.org/10.1016/j.addr.2018.07.003
  9. Veluthakal, R., Chepurny, O.G., Leech, C.A., Schwede, F., Holz, G.G., & Thurmond, D.C. (2018). Restoration of Glucose-Stimulated Cdc42-Pak1 Activation and Insulin Secretion by a Selective Epac Activator in Type 2 Diabetic Human Islets. Diabetes, Epub ahead of print. https://doi.org/10.2337/db17-1174
  10. Wang, Y., Hoinka, J., Liang, Y., Adamus, T., Swiderski, P., & Przytycka, T.M. (2018). AptaBlocks: Designing RNA complexes and accelerating RNA-based drug delivery systems. Nucleic Acids Research, Epub ahead of print. https://doi.org/10.1093/nar/gky577
  11. Dieli-Conwright, C.M., Courneya, K.S., Demark-Wahnefried, W., Sami, N., Lee, K., Buchanan, T.A., Spicer, D., Tripathy, D., Bernstein, L., & Mortimer, J.E. (2018). Reply to E. Parkin et al. Journal of Clinical Oncology, 36(20), 2129-30. https://doi.org/10.1200/jco.2018.78.7754
  12. Wang, J., Yuan, Z., Cui, Y., Xie, R., Yang, G., Kassab, M.A., Wang, M., Ma, Y., Wu, C., Yu, X., & Liu, X. (2018). Molecular basis for the inhibition of the methyl-lysine binding function of 53BP1 by TIRR. Nat Commun, 9(1), 2689. https://doi.org/10.1038/s41467-018-05174-9
  13. Geng, A., Qiu, R., Murai, K., Liu, J., Wu, X., Zhang, H., Farhoodi, H., Duong, N., Jiang, M., Yee, J.K., Tsark, W., & Lu, Q. (2018). KIF20A/MKLP2 regulates the division modes of neural progenitor cells during cortical development. Nat Commun, 9(1), 2707. https://doi.org/10.1038/s41467-018-05152-1
  14. Li, M., Xu, X., Chang, C.W., Zheng, L., Shen, B., & Liu, Y. (2018). SUMO2 conjugation of PCNA facilitates chromatin remodeling to resolve transcription-replication conflicts. Nat Commun, 9(1), 2706. https://doi.org/10.1038/s41467-018-05236-y
  15. Li, Z., Liu, B., Jin, W., Wu, X., Zhou, M., Liu, V.Z., Goel, A., Shen, Z., Zheng, L., & Shen, B. (2018). hDNA2 nuclease/helicase promotes centromeric DNA replication and genome stability. EMBO Journal, 37(14), e96729. https://doi.org/10.15252/embj.201796729
  16. Nardi, I., Reno, T., Yun, X., Sztain, T., Wang, J., Dai, H., Zheng, L., Kim, J., & Raz, D. (2018). Triptolide inhibits Wnt signaling in NSCLC through upregulation of multiple Wnt inhibitory factors via epigenetic modifications to Histone H3. International Journal of Cancer, Epub ahead of print. https://doi.org/10.1002/ijc.31756
  17. Zhang, X.H., Nam, S., Wu, J., Chen, C.H., Liu, X., Li, H., McKeithan, T., Gong, Q., Chan, W.C., Yin, H.H., Yuan, Y.C., Pillai, R., Querfeld, C., Horne, D., Chen, Y., & Rosen, S.T. (2018). Multi-Kinase Inhibitor with Anti-p38gamma Activity in Cutaneous T-Cell Lymphoma. Journal of Investigative Dermatology, Epub ahead of print. https://doi.org/10.1016/j.jid.2018.04.030
  18. Wang, S.S., Carrington, M., Berndt, S.I., Slager, S.L., Bracci, P.M., Voutsinas, J., Cerhan, J.R., Smedby, K.E., Hjalgrim, H., Vijai, J., Morton, L.M., Vermeulen, R., Paltiel, O., Vajdic, C.M., Linet, M.S., Nieters, A., de Sanjose, S., Cozen, W., Brown, E.E., Turner, J., Spinelli, J.J., Zheng, T., Birmann, B.M., Flowers, C.R., Becker, N., Holly, E.A., Kane, E., Weisenburger, D., Maynadie, M., Cocco, P., Albanes, D., Weinstein, S.J., Teras, L.R., Diver, W.R., Lax, S.J., Travis, R.C., Kaaks, R., Riboli, E., Benavente, Y., Brennan, P., McKay, J., Delfau-Larue, M.H., Link, B.K., Magnani, C., Ennas, M.G., Latte, G., Feldman, A.L., Doo, N.W., Giles, G.G., Southey, M.C., Milne, R.L., Offit, K., Musinsky, J., Arslan, A.A., Purdue, M.P., Adami, H.O., Melbye, M., Glimelius, B., Conde, L., Camp, N.J., Glenn, M., Curtin, K., Clavel, J., Monnereau, A., Cox, D.G., Ghesquieres, H., Salles, G., Bofetta, P., Foretova, L., Staines, A., Davis, S., Severson, R.K., Lan, Q., Brooks-Wilson, A., Smith, M.T., Roman, E., Kricker, A., Zhang, Y., Kraft, P., Chanock, S.J., Rothman, N., Hartge, P., & Skibola, C.F. (2018). HLA Class I and II Diversity Contributes to the Etiologic Heterogeneity of Non-Hodgkin Lymphoma Subtypes. Cancer Research, 78(14), 4086-96. https://doi.org/10.1158/0008-5472.can-17-2900
  19. Agarwal, N., Lanman, R.B., & Pal, S.K. (2018). Regarding the Congruence Between 2 Circulating Tumor DNA Sequencing Assays. JAMA Oncol, Epub ahead of print. https://doi.org/10.1001/jamaoncol.2018.2317
  20. Aldoss, I., Capelletti, M., Park, J., Pistofidis, R.S., Pillai, R., Stiller, T., Sanchez, J.F., Forman, S.J., Ghobrial, I.M., & Krishnan, A. (2018). Acute lymphoblastic leukemia as a clonally unrelated second primary malignancy after multiple myeloma. Leukemia, Epub ahead of print. https://doi.org/10.1038/s41375-018-0213-y
  21. Armenian, S.H., Armstrong, G.T., Aune, G., Chow, E.J., Ehrhardt, M.J., Ky, B., Moslehi, J., Mulrooney, D.A., Nathan, P.C., Ryan, T.D., van der Pal, H.J., van Dalen, E.C., & Kremer, L.C.M. (2018). Cardiovascular Disease in Survivors of Childhood Cancer: Insights Into Epidemiology, Pathophysiology, and Prevention. Journal of Clinical Oncology, 36(21), 2135-44. https://doi.org/10.1200/jco.2017.76.3920
  22. Margolin, K., Morishima, C., Velcheti, V., Miller, J.S., Lee, S.M., Silk, A.W., Holtan, S.G., Lacroix, A.M., Fling, S.P., Kaiser, J.C., Egan, J.O., Jones, M., Rhode, P.R., Rock, A.D., Cheever, M.A., Wong, H.C., & Ernstoff, M.S. (2018). Phase I Trial of ALT-803, a Novel Recombinant Interleukin-15 Complex, in Patients with Advanced Solid Tumors. Clinical Cancer Research, Epub ahead of print. https://doi.org/10.1158/1078-0432.ccr-18-0945
  23. Bhanvadia, S., & Pal, S.K. (2018). Cytoreductive nephrectomy: questions remain after CARMENA. Nat Rev Urol, 15(9), 530-2. https://doi.org/10.1038/s41585-018-0064-3
  24. Smith, L.J., Wright, J., Clark, G., Ul-Hasan, T., Jin, X., Fong, A., Chandra, M., St Martin, T., Rubin, H., Knowlton, D., Ellsworth, J.L., Fong, Y., Wong, K.K., Jr., & Chatterjee, S. (2018). Stem cell-derived clade F AAVs mediate high-efficiency homologous recombination-based genome editing. Proceedings of the National Academy of Sciences of the United States of America, 115(31), E7379-e88. https://doi.org/10.1073/pnas.1802343115
  25. Ghose, J., Viola, D., Terrazas, C., Caserta, E., Troadec, E., Khalife, J., Gunes, E.G., Sanchez, J., McDonald, T., Marcucci, G., Kaur, B., Rosenzweig, M., Keats, J., Rosen, S., Krishnan, A., Satoskar, A.R., Hofmeister, C.C., & Pichiorri, F. (2018). Daratumumab induces CD38 internalization and impairs myeloma cell adhesion. Oncoimmunology, Epub ahead of print. https://doi.org/10.1080/2162402X.2018.1486948
  26. Soto-Perez-de-Celis, E., Li, D., Yuan, Y., Lau, Y.M., & Hurria, A. (2018). Functional versus chronological age: geriatric assessments to guide decision making in older patients with cancer. Lancet Oncology, 19(6), e305-e16. https://doi.org/10.1016/s1470-2045(18)30348-6
  27. Moin, A.S.M., Cory, M., Choi, J., Ong, A., Dhawan, S., Dry, S.M., Butler, P.C., Rizza, R.A., & Butler, A.E. (2018). Increased Chromogranin A-Positive Hormone-Negative Cells in Chronic Pancreatitis. Journal of Clinical Endocrinology and Metabolism, 103(6), 2126-35. https://doi.org/10.1210/jc.2017-01562
  28. Kundu, M., He, T.F., Lu, Y., Wang, L., & Zhong, D. (2018). Short-Range Electron Transfer in Reduced Flavodoxin: Ultrafast Nonequilibrium Dynamics Coupled with Protein Fluctuations. J Phys Chem Lett, 9(11), 2782-90. https://doi.org/10.1021/acs.jpclett.8b00882
  29. Yuh, B., Chan, K., & Wilson, T. (2018). Robotic Cystectomy-Moving from Innovation to Measurable Impact. European Urology, 74(4), 472-3. https://doi.org/10.1016/j.eururo.2018.05.028
  30. Todhunter, M.E., Sayaman, R.W., Miyano, M., & LaBarge, M.A. (2018). Tissue aging: the integration of collective and variant responses of cells to entropic forces over time. Current Opinion in Cell Biology, 54, 121-9. https://doi.org/10.1016/j.ceb.2018.05.016
  31. Aldoss, I., Stiller, T., Tsai, N.C., Song, J.Y., Cao, T., Bandara, N.A., Salhotra, A., Khaled, S., Aribi, A., Al Malki, M.M., Mei, M., Ali, H., Spielberger, R., O'Donnell, M., Snyder, D., Slavin, T., Nakamura, R., Stein, A.S., Forman, S.J., Marcucci, G., & Pullarkat, V. (2018). Therapy-related acute lymphoblastic leukemia has distinct clinical and cytogenetic features compared to de novo acute lymphoblastic leukemia, but outcomes are comparable in transplanted patients. Haematologica, Epub ahead of print. https://doi.org/10.3324/haematol.2018.193599
  32. Salgia, R., Jolly, M.K., Dorff, T., Lau, C., Weninger, K., Orban, J., & Kulkarni, P. (2018). Prostate-Associated Gene 4 (PAGE4): Leveraging the Conformational Dynamics of a Dancing Protein Cloud as a Therapeutic Target. J Clin Med, 7(6), 156. https://doi.org/10.3390/jcm7060156
  33. Castanotto, D., Zhang, X., Alluin, J., Zhang, X., Ruger, J., Armstrong, B., Rossi, J., Riggs, A., & Stein, C.A. (2018). A stress-induced response complex (SIRC) shuttles miRNAs, siRNAs, and oligonucleotides to the nucleus. Proceedings of the National Academy of Sciences of the United States of America, 115(25), E5756-E65. https://doi.org/10.1073/pnas.1721346115
  34. Kidambi, T.D., Terdiman, J.P., El-Nachef, N., Singh, A., Kattah, M.G., & Lee, J.K. (2018). Effects of Electronic Chromoendoscopy on Detection of Adenomas During Colonoscopy. Clin Gastroenterol Hepatol, Epub ahead of print. https://doi.org/10.1016/j.cgh.2018.06.024
  35. Das, S., Reddy, M.A., Senapati, P., Stapleton, K., Lanting, L., Wang, M., Amaram, V., Ganguly, R., Zhang, L., Devaraj, S., Schones, D.E., & Natarajan, R. (2018). Diabetes Mellitus-Induced Long Noncoding RNA Dnm3os Regulates Macrophage Functions and Inflammation via Nuclear Mechanisms. Arteriosclerosis Thrombosis and Vascular Biology, Epub ahead of print. https://doi.org/10.1161/atvbaha.117.310663
  36. Bhargava, R., Sandhu, M., Muk, S., Lee, G., Vaidehi, N., & Stark, J.M. (2018). C-NHEJ without indels is robust and requires synergistic function of distinct XLF domains. Nat Commun, 9(1), 2484. https://doi.org/10.1038/s41467-018-04867-5
  37. Chen, R.W., Palmer, J.M., Tomassetti, S., Popplewell, L.L., Alluin, J., Chomchan, P., Nademanee, A.P., Siddiqi, T., Tsai, N.C., Chen, L., Zuo, F., Abary, R., Cai, J.L., Herrera, A.F., Rossi, J.J., Rosen, S.T., Forman, S.J., Kwak, L.W., & Holmberg, L.A. (2018). Multi-center phase II trial of bortezomib and rituximab maintenance combination therapy in patients with mantle cell lymphoma after consolidative autologous stem cell transplantation. J Hematol Oncol, 11(1), 87. https://doi.org/10.1186/s13045-018-0631-3
  38. de Velasco, G., Wankowicz, S.A., Madison, R., Ali, S.M., Norton, C., Duquette, A., Ross, J.S., Bosse, D., Lalani, A.A., Miller, V.A., Stephens, P.J., Young, L., Hakimi, A.A., Signoretti, S., Pal, S.K., & Choueiri, T.K. (2018). Targeted genomic landscape of metastases compared to primary tumours in clear cell metastatic renal cell carcinoma. British Journal of Cancer, 118(9), 1238-42. https://doi.org/10.1038/s41416-018-0064-3
  39. Pal, S.K., Hoffman-Censits, J., Zheng, H., Kaiser, C., Tayama, D., & Bellmunt, J. (2018). Atezolizumab in Platinum-treated Locally Advanced or Metastatic Urothelial Carcinoma: Clinical Experience from an Expanded Access Study in the United States. European Urology, 73(5), 800-6. https://doi.org/10.1016/j.eururo.2018.02.010
  40. Reckamp, K.L. (2018). Targeted Therapy for Patients With Metastatic Non-Small Cell Lung Cancer. Journal of the National Comprehensive Cancer Network, 16(5s), 601-4. https://doi.org/10.6004/jnccn.2018.0046
  41. Sun, W., Liu, H., Kim, Y., Karras, N., Pawlowska, A., Toomey, D., Kyono, W., Gaynon, P., Rosenthal, J., & Stein, A. (2018). First pediatric experience of SL-401, a CD123-targeted therapy, in patients with blastic plasmacytoid dendritic cell neoplasm: Report of three cases. Journal of Hematology and Oncology, 11(1), 61. https://doi.org/10.1186/s13045-018-0604-6
  42. Zhang, B., Nguyen, L.X.T., Li, L., Zhao, D., Kumar, B., Wu, H., Lin, A., Pellicano, F., Hopcroft, L., Su, Y.L., Copland, M., Holyoake, T.L., Kuo, C.J., Bhatia, R., Snyder, D.S., Ali, H., Stein, A.S., Brewer, C., Wang, H., McDonald, T., Swiderski, P., Troadec, E., Chen, C.C., Dorrance, A., Pullarkat, V., Yuan, Y.C., Perrotti, D., Carlesso, N., Forman, S.J., Kortylewski, M., Kuo, Y.H., & Marcucci, G. (2018). Bone marrow niche trafficking of miR-126 controls the self-renewal of leukemia stem cells in chronic myelogenous leukemia. Nature Medicine, 24(4), 450-62. https://doi.org/10.1038/nm.4499
  43. Aslamy, A., Oh, E., Ahn, M., Moin, A.S.M., Chang, M., Duncan, M., Hacker-Stratton, J., El-Shahawy, M., Kandeel, F., DiMeglio, L.A., & Thurmond, D.C. (2018). Exocytosis Protein DOC2B as a Biomarker of Type 1 Diabetes. Journal of Clinical Endocrinology and Metabolism, 103(5), 1966-76. https://doi.org/10.1210/jc.2017-02492
  44. Chen, B.T., Sethi, S.K., Jin, T., Patel, S.K., Ye, N., Sun, C.L., Rockne, R.C., Haacke, E.M., Root, J.C., Saykin, A.J., Ahles, T.A., Holodny, A.I., Prakash, N., Mortimer, J., Waisman, J., Yuan, Y., Somlo, G., Li, D., Yang, R., Tan, H., Katheria, V., Morrison, R., & Hurria, A. (2018). Assessing brain volume changes in older women with breast cancer receiving adjuvant chemotherapy: A brain magnetic resonance imaging pilot study. Breast Cancer Research, 20(1), 38. https://doi.org/10.1186/s13058-018-0965-3
  45. Weist, M.R., Starr, R., Aguilar, B., Chea, J., Miles, J., Poku, E., Gerdts, E., Yang, X., Priceman, S., Forman, S., Colcher, D., Brown, C., & Shively, J. (2018). Positron emission tomography of adoptively transferred chimeric antigen receptor T cells with Zirconium-89 oxine. Journal of Nuclear Medicine, Epub ahead of print. https://doi.org/10.2967/jnumed.117.206714
  46. Lewis, A., Raoof, M., Ituarte, P.H.G., Williams, J., Melstrom, L., Li, D., Lee, B., & Singh, G. (2018). Resection of the Primary Gastrointestinal Neuroendocrine Tumor Improves Survival with or without Liver Treatment. Annals of Surgery, Epub ahead of print. https://doi.org/10.1097/sla.0000000000002809
  47. Hassamal, S., Miotto, K., Dale, W., & Danovitch, I. (2018). Tramadol: Understanding the Risk of Serotonin Syndrome and Seizures. American Journal of Medicine, Epub ahead of print. https://doi.org/10.1016/j.amjmed.2018.04.025
  48. Agarwal, N., Pal, S.K., Hahn, A.W., Nussenzveig, R.H., Pond, G.R., Gupta, S.V., Wang, J., Bilen, M.A., Naik, G., Ghatalia, P., Hoimes, C.J., Gopalakrishnan, D., Barata, P.C., Drakaki, A., Faltas, B.M., Kiedrowski, L.A., Lanman, R.B., Nagy, R.J., Vogelzang, N.J., Boucher, K.M., Vaishampayan, U.N., Sonpavde, G., & Grivas, P. (2018). Characterization of metastatic urothelial carcinoma via comprehensive genomic profiling of circulating tumor DNA. Cancer, 124(10), 2115-24. https://doi.org/10.1002/cncr.31314
  49. Chlebowski, R.T., Aragaki, A.K., Anderson, G.L., Simon, M.S., Manson, J.E., Neuhouser, M.L., Pan, K., Stefanic, M.L., Rohan, T.E., Lane, D., Qi, L., Snetselaar, L., & Prentice, R.L. (2018). Association of Low-Fat Dietary Pattern With Breast Cancer Overall Survival: A Secondary Analysis of the Women's Health Initiative Randomized Clinical Trial. JAMA Oncol, e181212. https://doi.org/10.1001/jamaoncol.2018.1212
  50. Chung, C.P., Lee, S.J., & Wakabayashi, M.T. (2018). Uterine and cervical cancer with irreducible pelvic organ prolapse. American Journal of Obstetrics and Gynecology, Epub ahead of print. https://doi.org/10.1016/j.ajog.2018.05.021
  51. Aldoss, I., & Song, J.Y. (2018). Extramedullary relapse of KMT2A(MLL)-rearranged acute lymphoblastic leukemia with lineage switch following blinatumomab. Blood, 131(22), 2507. https://doi.org/10.1182/blood-2018-02-834911