Recent Publications

  1. Dieli-Conwright, C.M., Courneya, K.S., Demark-Wahnefried, W., Sami, N., Lee, K., Sweeney, F.C., Stewart, C., Buchanan, T.A., Spicer, D., Tripathy, D., Bernstein, L., & Mortimer, J.E. (2018). Aerobic and resistance exercise improves physical fitness, bone health, and quality of life in overweight and obese breast cancer survivors: a randomized controlled trial. Breast Cancer Research, 20, Article number: 124. https://doi.org/10.1186/s13058-018-1051-6
  2. Liu, J., Geng, A., Wu, X., Lin, R.J., & Lu, Q. (2018). Alternative RNA Splicing Associated With Mammalian Neuronal Differentiation. Cerebral Cortex, 28(8), 2810-6. https://doi.org/10.1093/cercor/bhx160
  3. Gu, L., Lingeman, R., Yakushijin, F., Sun, E., Cui, Q., Chao, J., Hu, W., Li, H., Hickey, R.J., Stark, J.M., Yuan, Y.C., Chen, Y., Vonderfecht, S.L., Synold, T.W., Shi, Y., Reckamp, K.L., Horne, D., & Malkas, L.H. (2018). The Anticancer Activity of a First-in-class Small-molecule Targeting PCNA. Clinical Cancer Research, 24(23), 6053-65. https://doi.org/10.1158/1078-0432.CCR-18-0592
  4. Wang, Y., Hoinka, J., Liang, Y., Adamus, T., Swiderski, P., & Przytycka, T.M. (2018). AptaBlocks: Designing RNA complexes and accelerating RNA-based drug delivery systems. Nucleic Acids Research, 46(16), 8133-42. https://doi.org/10.1093/nar/gky577
  5. Seewaldt, V.L. (2018). Aspirin and Chemoprevention-Have We Arrived? JAMA Oncol, 4(12), 1668-9. https://doi.org/10.1001/jamaoncol.2018.4138
  6. Soto-Perez-de-Celis, E., Sun, C.L., Tew, W.P., Mohile, S.G., Gajra, A., Klepin, H.D., Owusu, C., Gross, C.P., Muss, H.B., Lichtman, S.M., Chapman, A.E., Cohen, H.J., Dale, W., Kim, H., Fernandes, S., Katheria, V., & Hurria, A. (2018). Association between patient-reported hearing and visual impairments and functional, psychological, and cognitive status among older adults with cancer. Cancer, 124(15), 3249-56. https://doi.org/10.1002/cncr.31540
  7. Lin, H.H., Chung, Y., Cheng, C.T., Ouyang, C., Fu, Y., Kuo, C.Y., Chi, K.K., Sadeghi, M., Chu, P., Kung, H.J., Li, C.F., Limesand, K.H., & Ann, D.K. (2018). Autophagic reliance promotes metabolic reprogramming in oncogenic KRAS-driven tumorigenesis. Autophagy, 14(9), 1481-98. https://doi.org/10.1080/15548627.2018.1450708
  8. Budde, L.E., Wu, D., Martin, D.B., Philip, M., Shustov, A.R., Smith, S.D., Gooley, T.A., Chen, T.L., Libby, E.N., Chen, E.Y., Kojouri, K., Langerak, A., Roden, J.E., Press, O.W., & Gopal, A.K. (2018). Bendamustine with rituximab, etoposide and carboplatin (T(R)EC) in relapsed or refractory aggressive lymphoma: a prospective multicentre phase 1/2 clinical trial. British Journal of Haematology, 183(4), 601-7. https://doi.org/10.1111/bjh.15585 
  9. Agarwal, N., Nussenzveig, R., & Pal, S.K. (2018). Biomarkers in renal-cell carcinoma: building on clinical paradigms. Lancet Oncology, 19(12), 1560-1. https://doi.org/10.1016/S1470-2045(18)30674-0
  10. Mhaskar, R., & Djulbegovic, B. (2018). Bisphosphonates for Patients Diagnosed With Multiple Myeloma. JAMA, 320(14), 1483-4. https://doi.org/10.1001/jama.2018.13773
  11. Ring, A., Nguyen, C., Smbatyan, G., Tripathy, D., Yu, M., Press, M., Kahn, M., & Lang, J.E. (2018). CBP/beta-Catenin/FOXM1 Is a Novel Therapeutic Target in Triple Negative Breast Cancer. Cancers, 10(12), Article number: 525. https://doi.org/10.3390/cancers10120525
  12. Chen, L., Youssef, Y., Robinson, C., Ernst, G.F., Carson, M.Y., Young, K.A., Scoville, S.D., Zhang, X., Harris, R., Sekhri, P., Mansour, A.G., Chan, W.K., Nalin, A.P., Mao, H.C., Hughes, T., Mace, E.M., Pan, Y., Rustagi, N., Chatterjee, S.S., Gunaratne, P.H., Behbehani, G.K., Mundy-Bosse, B.L., Caligiuri, M.A., & Freud, A.G. (2018). CD56 Expression Marks Human Group 2 Innate Lymphoid Cell Divergence from a Shared NK Cell and Group 3 Innate Lymphoid Cell Developmental Pathway. Immunity, 49(3), 464-76.e4. https://doi.org/10.1016/j.immuni.2018.08.010
  13. Scoville, S.D., Freud, A.G., & Caligiuri, M.A. (2018). Cellular pathways in the development of human and murine innate lymphoid cells. Current Opinion in Immunology, 56, 100-6. https://doi.org/10.1016/j.coi.2018.11.003
  14. Li, R., Hou, W.H., Chao, J., Woo, Y., Glaser, S., Amini, A., Nelson, R.A., & Chen, Y.J. (2018). Chemoradiation Improves Survival Compared With Chemotherapy Alone in Unresected Nonmetastatic Gastric Cancer. Journal of the National Comprehensive Cancer Network, 16(8), 950-8. https://doi.org/10.6004/jnccn.2018.7030
  15. Ogba, N., Arwood, N.M., Bartlett, N.L., Bloom, M., Brown, P., Brown, C., Budde, E.L., Carlson, R., Farnia, S., Fry, T.J., Garber, M., Gardner, R.A., Gurschick, L., Kropf, P., Reitan, J.J., Sauter, C., Shah, B., Shpall, E.J., & Rosen, S.T. (2018). Chimeric Antigen Receptor T-Cell Therapy. Journal of the National Comprehensive Cancer Network, 16(9), 1092-106. https://doi.org/10.6004/jnccn.2018.0073
  16. Tawbi, H.A., Forsyth, P.A., Algazi, A., Hamid, O., Hodi, F.S., Moschos, S.J., Khushalani, N.I., Lewis, K., Lao, C.D., Postow, M.A., Atkins, M.B., Ernstoff, M.S., Reardon, D.A., Puzanov, I., Kudchadkar, R.R., Thomas, R.P., Tarhini, A., Pavlick, A.C., Jiang, J., Avila, A., Demelo, S., & Margolin, K. (2018). Combined Nivolumab and Ipilimumab in Melanoma Metastatic to the Brain. New England Journal of Medicine, 379(8), 722-30. https://doi.org/10.1056/NEJMoa1805453
  17. Fong, Y. (2018). Combining Antiviral Therapy With Tumor Resection as Optimal Treatment for Hepatocellular Carcinoma. JAMA Surg, 153(10), e182728. https://doi.org/10.1001/jamasurg.2018.2728
  18. Massarelli, E., William, W., Johnson, F., Kies, M., Ferrarotto, R., Guo, M., Feng, L., Lee, J.J., Tran, H., Kim, Y.U., Haymaker, C., Bernatchez, C., Curran, M., Zecchini Barrese, T., Rodriguez Canales, J., Wistuba, I., Li, L., Wang, J., van der Burg, S.H., Melief, C.J., & Glisson, B. (2018). Combining Immune Checkpoint Blockade and Tumor-Specific Vaccine for Patients With Incurable Human Papillomavirus 16-Related Cancer: A Phase 2 Clinical Trial. JAMA Oncol, 5(1), 67-73. https://doi.org/10.1001/jamaoncol.2018.4051
  19. Amini, A., Eguchi, M., Jones, B.L., Stokes, W.A., Gupta, A., McDermott, J.D., Massarelli, E., Bradley, C.J., & Karam, S.D. (2018). Comparing outcomes of concurrent chemotherapy regimens in patients 65 years old or older with locally advanced oropharyngeal carcinoma. Cancer, 124(22), 4322-31. https://doi.org/10.1002/cncr.31740
  20. Priceman, S.J., Gerdts, E.A., Tilakawardane, D., Kennewick, K.T., Murad, J.P., Park, A.K., Jeang, B., Yamaguchi, Y., Yang, X., Urak, R., Weng, L.H., Chang, W.C., Wright, S., Pal, S., Reiter, R.E., Wu, A.M., Brown, C.E., & Forman, S.J. (2018). Co-stimulatory signaling determines tumor antigen sensitivity and persistence of CAR T cells targeting PSCA plus metastatic prostate cancer. Oncoimmunology, 7(2), Article number: e1380764. https://doi.org/10.1080/2162402x.2017.1380764
  21. Das, S., Reddy, M.A., Senapati, P., Stapleton, K., Lanting, L., Wang, M., Amaram, V., Ganguly, R., Zhang, L.X., Devaraj, S., Schones, D.E., & Natarajan, R. (2018). Diabetes Mellitus-Induced Long Noncoding RNA Dnm3os Regulates Macrophage Functions and Inflammation via Nuclear Mechanisms. Arteriosclerosis Thrombosis and Vascular Biology, 38(8), 1806-20. https://doi.org/10.1161/atvbaha.117.310663
  22. Tsai, W.K., Zettlitz, K.A., Tavare, R., Kobayashi, N., Reiter, R.E., & Wu, A.M. (2018). Dual-Modality ImmunoPET/Fluorescence Imaging of Prostate Cancer with an Anti-PSCA Cys-Minibody. Theranostics, 8(21), 5903-14. https://doi.org/10.7150/thno.27679
  23. Murad, J.P., Kozlowska, A.K., Lee, H.J., Ramamurthy, M., Chang, W.C., Yazaki, P., Colcher, D., Shively, J., Cristea, M., Forman, S.J., & Priceman, S.J. (2018). Effective Targeting of TAG72(+) Peritoneal Ovarian Tumors via Regional Delivery of CAR-Engineered T Cells. Frontiers in Immunology, 9, Article number: 2268. https://doi.org/10.3389/fimmu.2018.02268
  24. Ogura, M., Sancho, J.M., Cho, S.G., Nakazawa, H., Suzumiya, J., Tumyan, G., Kim, J.S., Lennard, A., Mariz, J., Ilyin, N., Jurczak, W., Lopez Martinez, A., Samoilova, O., Zhavrid, E., Yanez Ruiz, E., Trneny, M., Popplewell, L., Coiffier, B., Buske, C., Kim, W.S., Lee, S.J., Lee, S.Y., Bae, Y.J., & Kwak, L.W. (2018). Efficacy, pharmacokinetics, and safety of the biosimilar CT-P10 in comparison with rituximab in patients with previously untreated low-tumour-burden follicular lymphoma: a randomised, double-blind, parallel-group, phase 3 trial. Lancet Haematol, 5(11), e543-e53. https://doi.org/10.1016/S2352-3026(18)30157-1
  25. Ghosh, S., Bierig, T., Lee, S., Jana, S., Löhle, A., Schnapp, G., Tautermann, C.S., & Vaidehi, N. (2018). Engineering Salt Bridge Networks between Transmembrane Helices Confers Thermostability in G-Protein-Coupled Receptors. Journal of Chemical Theory and Computation, 14(12), 6574–85. https://doi.org/10.1021/acs.jctc.8b00602
  26. Levit, L.A., Singh, H., Klepin, H.D., & Hurria, A. (2018). Expanding the Evidence Base in Geriatric Oncology: Action Items From an FDA-ASCO Workshop. Journal of the National Cancer Institute, 110(11), 1163-70. https://doi.org/10.1093/jnci/djy169
  27. Branciamore, S., Valo, Z., Li, M., Wang, J., Riggs, A.D., & Singer-Sam, J. (2018). Frequent monoallelic or skewed expression for developmental genes in CNS-derived cells and evidence for balancing selection. Proceedings of the National Academy of Sciences of the United States of America, 115(44), E10379-E86. https://doi.org/10.1073/pnas.1808652115
  28. Schork, A.J., Schork, M.A., & Schork, N.J. (2018). Genetic risks and clinical rewards. Nature Genetics, 50(9), 1210-1. https://doi.org/10.1038/s41588-018-0213-x
  29. Li, L., Tian, E., Chen, X., Chao, J., Klein, J., Qu, Q., Sun, G., Sun, G., Huang, Y., Warden, C.D., Ye, P., Feng, L., Li, X., Cui, Q., Sultan, A., Douvaras, P., Fossati, V., Sanjana, N.E., Riggs, A.D., & Shi, Y. (2018). GFAP Mutations in Astrocytes Impair Oligodendrocyte Progenitor Proliferation and Myelination in an hiPSC Model of Alexander Disease. Cell Stem Cell, 23(2), 239-51.e6. https://doi.org/10.1016/j.stem.2018.07.009
  30. Scoville, S.D., Nalin, A.P., Chen, L., Chen, L., Zhang, M.H., McConnell, K., Casas, S.B., Ernst, G., Al-Rahman Traboulsi, A., Hashi, N., Williams, M., Zhang, X., Hughes, T., Mishra, A., Benson, D.M., Saultz, J.N., Yu, J., Freud, A.G., Caligiuri, M.A., & Mundy-Bosse, B.L. (2018). Human AML activates the aryl hydrocarbon receptor pathway to impair NK cell development and function. Blood, 132(17), 1792-804. https://doi.org/10.1182/blood-2018-03-838474
  31. Egelston, C.A., Avalos, C., Tu, T.Y., Simons, D.L., Jimenez, G., Jung, J.Y., Melstrom, L., Margolin, K., Yim, J.H., Kruper, L., Mortimer, J., & Lee, P.P. (2018). Human breast tumor-infiltrating CD8(+) T cells retain polyfunctionality despite PD-1 expression. Nature Communications, 9, Article number: 4297. https://doi.org/10.1038/s41467-018-06653-9
  32. Slavin, T.P., Banks, K.C., Chudova, D., Oxnard, G.R., Odegaard, J.I., Nagy, R.J., Tsang, K.W.K., Neuhausen, S.L., Gray, S.W., Cristofanilli, M., Rodriguez, A.A., Bardia, A., Leyland-Jones, B., Janicek, M.F., Lilly, M., Sonpavde, G., Lee, C.E., Lanman, R.B., Meric-Bernstam, F., Kurzrock, R., & Weitzel, J.N. (2018). Identification of Incidental Germline Mutations in Patients With Advanced Solid Tumors Who Underwent Cell-Free Circulating Tumor DNA Sequencing. Journal of Clinical Oncology, 36(35), 3459-65. https://doi.org/10.1200/JCO.18.00328
  33. Thomaidou, S., Zaldumbide, A., & Roep, B.O. (2018). Islet stress, degradation and autoimmunity. Diabetes, Obesity & Metabolism, 20 Suppl 2, 88-94. https://doi.org/10.1111/dom.13387
  34. Leung, A., & Natarajan, R. (2018). Long Noncoding RNAs in Diabetes and Diabetic Complications. Antioxidants and Redox Signaling, 29(11), 1064-73. https://doi.org/10.1089/ars.2017.7315
  35. Leung, A., Trac, C., Kato, H., Costello, K.R., Chen, Z., Natarajan, R., & Schones, D.E. (2018). LTRs activated by Epstein-Barr virus-induced transformation of B cells alter the transcriptome. Genome Research, 28(12), 1791-8. https://doi.org/10.1101/gr.233585.117
  36. Poultsidi, A., Dimopoulos, Y., He, T.F., Chavakis, T., Saloustros, E., Lee, P.P., & Petrovas, C. (2018). Lymph Node Cellular Dynamics in Cancer and HIV: What Can We Learn for the Follicular CD4 (Tfh) Cells? Frontiers in Immunology, 9, Article number: 2233. https://doi.org/10.3389/fimmu.2018.02233
  37. Singhal, J., Singhal, P., Horne, D., Salgia, R., Awasthi, S., & Singhal, S.S. (2018). Metastasis of breast tumor cells to brain is suppressed by targeting RLIP alone and in combination with 2 '-Hydroxyflavanone. Cancer Letters, 438, 144-53. https://doi.org/10.1016/j.canlet.2018.09.015
  38. Liu, X., Cao, M., Palomares, M., Wu, X., Li, A., Yan, W., Fong, M.Y., Chan, W.C., & Wang, S.E. (2018). Metastatic breast cancer cells overexpress and secrete miR-218 to regulate type i collagen deposition by osteoblasts. Breast Cancer Research, 20, Article number: 127. https://doi.org/10.1186/s13058-018-1059-y
  39. Pichiorri, F. (2018). Mice no longer immune to immunomodulatory drugs. Blood, 132(14), 1470-1. https://doi.org/10.1182/blood-2018-08-868083
  40. Maughan, B.L., Pal, S.K., Gill, D., Boucher, K., Martin, C., Salgia, M., Nussenzveig, R., Liu, T., Hawks, J.L., Batten, J., Nachaegari, G., Stephenson, R., Lowrance, W., Jones, J., Dechet, C., & Agarwal, N. (2018). Modulation of Premetastatic Niche by the Vascular Endothelial Growth Factor Receptor Tyrosine Kinase Inhibitor Pazopanib in Localized High-Risk Prostate Cancer Followed by Radical Prostatectomy: A Phase II Randomized Trial. Oncologist, 23(12), 1413-e151. https://doi.org/10.1634/theoncologist.2018-0652
  41. Lv, Z.Y., Yuan, L.M., Atkison, J.H., Williams, K.M., Vega, R., Sessions, E.H., Divlianska, D.B., Davies, C., Chen, Y., & Olsen, S.K. (2018). Molecular mechanism of a covalent allosteric inhibitor of SUMO E1 activating enzyme. Nature Communications, 9, Article number: 5145. https://doi.org/10.1038/s41467-018-07015-1
  42. Das, S., Zhang, E.L., Senapati, P., Amaram, V., Reddy, M.A., Stapleton, K., Leung, A., Lanting, L., Wang, M., Chen, Z., Kato, M., Oh, H.J., Guo, Q.Y., Zhang, X., Zhang, B.Y., Zhang, H.T., Zhao, Q.H., Wang, W., Wu, Y.J., & Natarajan, R. (2018). A Novel Angiotensin II-Induced Long Noncoding RNA Giver Regulates Oxidative Stress, Inflammation, and Proliferation in Vascular Smooth Muscle Cells. Circulation Research, 123(12), 1298-312. https://doi.org/10.1161/circresaha.118.313207
  43. Salunkhe, V.A., Veluthakal, R., Kahn, S.E., & Thurmond, D.C. (2018). Novel approaches to restore beta cell function in prediabetes and type 2 diabetes. Diabetologia, 61(9), 1895-901. https://doi.org/10.1007/s00125-018-4658-3
  44. Xu, B., Ma, R., Russell, L., Yoo, J.Y., Han, J., Cui, H., Yi, P., Zhang, J., Nakashima, H., Dai, H., Chiocca, E.A., Kaur, B., Caligiuri, M.A., & Yu, J. (2018). An oncolytic herpesvirus expressing E-cadherin improves survival in mouse models of glioblastoma. Nature Biotechnology, 37, 45-62. https://doi.org/10.1038/nbt.4302
  45. Sun, W.L., Malvar, J., Sposto, R., Verma, A., Wilkes, J.J., Dennis, R., Heym, K., Laetsch, T.W., Widener, M., Rheingold, S.R., Oesterheld, J., Hijiya, N., Sulis, M.L., Huynh, V., Place, A.E., Bittencourt, H., Hutchinson, R., Messinger, Y., Chang, B., Matioub, Y., Ziegler, D.S., Gardner, R., Cooper, T., Ceppi, F., Hermiston, M., Dalla-Pozza, L., Schultz, K.R., Gaynon, P., Wayne, A.S., & Whitlock, J.A. (2018). Outcome of children with multiply relapsed B-cell acute lymphoblastic leukemia: a therapeutic advances in childhood leukemia & lymphoma study. Leukemia, 32(11), 2316-25. https://doi.org/10.1038/s41375-018-0094-0
  46. Komatsu, H., Cook, C.A., Gonzalez, N., Medrano, L., Salgado, M., Sui, F., Li, J., Kandeel, F., Mullen, Y., & Tai, Y.C. (2018). Oxygen transporter for the hypoxic transplantation site. Biofabrication, 11(1), Article number: 015011. https://doi.org/10.1088/1758-5090/aaf2f0
  47. Chen, Q., Kassab, M.A., Dantzer, F., & Yu, X. (2018). PARP2 mediates branched poly ADP-ribosylation in response to DNA damage. Nature Communications, 9, 3233. https://doi.org/10.1038/s41467-018-05588-5
  48. Weist, M.R., Starr, R., Aguilar, B., Chea, J., Miles, J.K., Poku, E., Gerdts, E., Yang, X., Priceman, S.J., Forman, S.J., Colcher, D., Brown, C.E., & Shively, J.E. (2018). PET of Adoptively Transferred Chimeric Antigen Receptor T Cells with (89)Zr-Oxine. Journal of Nuclear Medicine, 59(10), 1531-7. https://doi.org/10.2967/jnumed.117.206714
  49. Fathi, A.T., Erba, H.P., Lancet, J.E., Stein, E.M., Ravandi, F., Faderl, S., Walter, R.B., Advani, A.S., DeAngelo, D.J., Kovacsovics, T.J., Jillella, A., Bixby, D., Levy, M.Y., O'Meara, M.M., Ho, P.A., Voellinger, J., & Stein, A.S. (2018). A phase 1 trial of vadastuximab talirine combined with hypomethylating agents in patients with CD33-positive AML. Blood, 132(11), 1125-33. https://doi.org/10.1182/blood-2018-03-841171
  50. Margolin, K., Morishima, C., Velcheti, V., Miller, J.S., Lee, S.M., Silk, A.W., Holtan, S.G., Lacroix, A.M., Fling, S.P., Kaiser, J.C., Egan, J.O., Jones, M., Rhode, P.R., Rock, A.D., Cheever, M.A., Wong, H.C., & Ernstoff, M.S. (2018). Phase I Trial of ALT-803, A Novel Recombinant IL15 Complex, in Patients with Advanced Solid Tumors. Clinical Cancer Research, 24(22), 5552-61. https://doi.org/10.1158/1078-0432.ccr-18-0945
  51. Golfetto, O., Wakefield, D.L., Cacao, E.E., Avery, K.N., Kenyon, V., Jorand, R., Tobin, S.J., Biswas, S., Gutierrez, J., Clinton, R., Ma, Y., Horne, D.A., Williams, J.C., & Jovanovic-Talisman, T. (2018). A Platform To Enhance Quantitative Single Molecule Localization Microscopy. Journal of the American Chemical Society, 140(40), 12785-97. https://doi.org/10.1021/jacs.8b04939
  52. Mohile, S.G., Dale, W., Somerfield, M.R., Schonberg, M.A., Boyd, C.M., Burhenn, P.S., Canin, B., Cohen, H.J., Holmes, H.M., Hopkins, J.O., Janelsins, M.C., Khorana, A.A., Klepin, H.D., Lichtman, S.M., Mustian, K.M., Tew, W.P., & Hurria, A. (2018). Practical Assessment and Management of Vulnerabilities in Older Patients Receiving Chemotherapy: ASCO Guideline for Geriatric Oncology. Journal of Clinical Oncology, 36(22), 2326-47. https://doi.org/10.1200/jco.2018.78.8687
  53. Querfeld, C., Leung, S., Myskowski, P.L., Curran, S.A., Goldman, D.A., Heller, G., Wu, X., Kil, S.H., Sharma, S., Finn, K.J., Horwitz, S., Moskowitz, A., Mehrara, B., Rosen, S.T., Halpern, A.C., & Young, J.W. (2018). Primary T Cells from Cutaneous T-cell Lymphoma Skin Explants Display an Exhausted Immune Checkpoint Profile. Cancer Immunol Res, 6(8), 900-9. https://doi.org/10.1158/2326-6066.cir-17-0270
  54. Feng, M., Marjon, K.D., Zhu, F., Weissman-Tsukamoto, R., Levett, A., Sullivan, K., Kao, K.S., Markovic, M., Bump, P.A., Jackson, H.M., Choi, T.S., Chen, J., Banuelos, A.M., Liu, J., Gip, P., Cheng, L., Wang, D., & Weissman, I.L. (2018). Programmed cell removal by calreticulin in tissue homeostasis and cancer. Nature Communications, 9, Article number: 3194. https://doi.org/10.1038/s41467-018-05211-7
  55. Slavin, T.P., Van Tongeren, L.R., Behrendt, C.E., Solomon, I., Rybak, C., Nehoray, B., Kuzmich, L., Niell-Swiller, M., Blazer, K.R., Tao, S., Yang, K., Culver, J.O., Sand, S., Castillo, D., Herzog, J., Gray, S.W., & Weitzel, J.N. (2018). Prospective Study of Cancer Genetic Variants: Variation in Rate of Reclassification by Ancestry. Journal of the National Cancer Institute, 110(10), 1059-66. https://doi.org/10.1093/jnci/djy027
  56. Shinde, A., Jones, B.L., Chen, Y.J., & Amini, A. (2018). Radiofrequency Ablation Versus Stereotactic Body Radiotherapy for Localized Hepatocellular Carcinoma: Does Radiation Dose Make a Difference? Journal of Clinical Oncology, 36(24), 2566-7. https://doi.org/10.1200/jco.2018.78.6012
  57. Cassady, K., Martin, P.J., & Zeng, D. (2018). Regulation of GVHD and GVL Activity via PD-L1 Interaction With PD-1 and CD80. Frontiers in Immunology, 9, Article number: 3061. https://doi.org/10.3389/fimmu.2018.03061
  58. Li, Y.J., Du, L., Aldana-Masangkay, G., Wang, X., Urak, R., Forman, S.J., Rosen, S.T., & Chen, Y. (2018). Regulation of miR-34b/c-targeted gene expression program by SUMOylation. Nucleic Acids Research, 46(14), 7108-23. https://doi.org/10.1093/nar/gky484
  59. Yoon, S., Wu, X., Armstrong, B., Habib, N., & Rossi, J.J. (2018). An RNA Aptamer Targeting the Receptor Tyrosine Kinase PDGFRalpha Induces Anti-tumor Effects through STAT3 and p53 in Glioblastoma. Mol Ther Nucleic Acids, 14, 131-41. https://doi.org/10.1016/j.omtn.2018.11.012
  60. Yuh, B., Chan, K., & Wilson, T. (2018). Robotic Cystectomy—Moving from Innovation to Measurable Impact. European Urology, 74(4), 472-3. https://doi.org/10.1016/j.eururo.2018.05.028
  61. Gao, H., Zhang, I.Y., Zhang, L., Song, Y., Liu, S., Ren, H., Liu, H., Zhou, H., Su, Y., Yang, Y., & Badie, B. (2018). S100B suppression alters polarization of infiltrating myeloid-derived cells in gliomas and inhibits tumor growth. Cancer Letters, 439, 91-100. https://doi.org/10.1016/j.canlet.2018.07.034
  62. Sun, J., He, X., Zhu, Y., Ding, Z., Dong, H., Feng, Y., Du, J., Wang, H., Wu, X., Zhang, L., Yu, X., Lin, A., McDonald, T., Zhao, D., Wu, H., Hua, W.K., Zhang, B., Feng, L., Tohyama, K., Bhatia, R., Oberdoerffer, P., Chung, Y.J., Aplan, P.D., Boultwood, J., Pellagatti, A., Khaled, S., Kortylewski, M., Pichiorri, F., Kuo, Y.H., Carlesso, N., Marcucci, G., Jin, H., & Li, L. (2018). SIRT1 Activation Disrupts Maintenance of Myelodysplastic Syndrome Stem and Progenitor Cells by Restoring TET2 Function. Cell Stem Cell, 23(3), 355-69.e9. https://doi.org/10.1016/j.stem.2018.07.018
  63. Wang, Y., Chu, J., Yi, P., Dong, W., Saultz, J., Wang, Y., Wang, H., Scoville, S., Zhang, J., Wu, L.C., Deng, Y., He, X., Mundy-Bosse, B., Freud, A.G., Wang, L.S., Caligiuri, M.A., & Yu, J. (2018). SMAD4 promotes TGF-beta-independent NK cell homeostasis and maturation and antitumor immunity. Journal of Clinical Investigation, 128(11), 5123-36. https://doi.org/10.1172/jci121227
  64. Weitzel, J.N., Chao, E.C., Nehoray, B., Van Tongeren, L.R., LaDuca, H., Blazer, K.R., Slavin, T., Pesaran, T., Rybak, C., Solomon, I., Niell-Swiller, M., Dolinsky, J.S., Castillo, D., Elliott, A., Gau, C.L., Speare, V., & Jasperson, K. (2018). Somatic TP53 variants frequently confound germ-line testing results. Genetics in Medicine, 20(8), 809-16. https://doi.org/10.1038/gim.2017.196
  65. Shrivastava, S., Charlins, P., Ackley, A., Embree, H., Dropulic, B., Akkina, R., Weinberg, M.S., & Morris, K.V. (2018). Stable Transcriptional Repression and Parasitism of HIV-1. Molecular Therapy - Nucleic Acids, 12, 12-8. https://doi.org/10.1016/j.omtn.2018.04.011
  66. Moreira, D., Adamus, T., Zhao, X., Su, Y.L., Zhang, Z., White, S.V., Swiderski, P., Lu, X., DePinho, R.A., Pal, S.K., & Kortylewski, M. (2018). STAT3 Inhibition Combined with CpG Immunostimulation Activates Antitumor Immunity to Eradicate Genetically Distinct Castration-Resistant Prostate Cancers. Clinical Cancer Research, 24(23), 5948-62. https://doi.org/10.1158/1078-0432.CCR-18-1277
  67. Xu, H., Shi, R., Han, W., Cheng, J., Xu, X., Cheng, K., Wang, L., Tian, B., Zheng, L., Shen, B., Hua, Y., & Zhao, Y. (2018). Structural basis of 5' flap recognition and protein-protein interactions of human flap endonuclease 1. Nucleic Acids Research, 46(21), 11315-25. https://doi.org/10.1093/nar/gky911
  68. Xu, X., Shi, R., Zheng, L., Guo, Z., Wang, L., Zhou, M., Zhao, Y., Tian, B., Truong, K., Chen, Y., Shen, B., Hua, Y., & Xu, H. (2018). SUMO-1 modification of FEN1 facilitates its interaction with Rad9-Rad1-Hus1 to counteract DNA replication stress. Journal of Molecular Cell Biology, 10(5), 460-74. https://doi.org/10.1093/jmcb/mjy047
  69. He, Z.H., Zhang, J., Huang, Z.F., Du, Q., Li, N., Zhang, Q., Chen, Y., & Sun, Z.M. (2018). Sumoylation of ROR gamma t regulates T(H)17 differentiation and thymocyte development. Nature Communications, 9, Article number: 4870. https://doi.org/10.1038/s41467-018-07203-z
  70. Li, R., Shinde, A., Chen, Y.J., Amini, A., Lee, S., Dellinger, T., Han, E., Wakabayashi, M., Nelson, R., Beriwal, S., & Glaser, S. (2018). Survival Benefit of Adjuvant Brachytherapy After Hysterectomy With Positive Surgical Margins in Cervical Cancer. International Journal of Radiation Oncology Biology Physics, 102(2), 373-82. https://doi.org/10.1016/j.ijrobp.2018.05.076
  71. Oh, E., Ahn, M., Afelik, S., Becker, T.C., Roep, B.O., & Thurmond, D.C. (2018). Syntaxin 4 expression in pancreatic β-cells promotes islet function and protects functional β-cell mass. Diabetes, 67(12), 2626-39. https://doi.org/10.2337/db18-0259
  72. Zhang, K., Wang, J., Yang, L., Yuan, Y.C., Tong, T.R., Wu, J., Yun, X., Bonner, M., Pangeni, R., Liu, Z., Yuchi, T., Kim, J.Y., & Raz, D.J. (2018). Targeting histone methyltransferase G9a inhibits growth and Wnt signaling pathway by epigenetically regulating HP1α and APC2 gene expression in non-small cell lung cancer 11 Medical and Health Sciences 1112 Oncology and Carcinogenesis 06 Biological Sciences 0601 Biochemistry and Cell Biology. Molecular Cancer, 17, Article number: 153. https://doi.org/10.1186/s12943-018-0896-8
  73. Hassamal, S., Miotto, K., Dale, W., & Danovitch, I. (2018). Tramadol: Understanding the Risk of Serotonin Syndrome and Seizures. American Journal of Medicine, 131(11), 1382 e1- e6. https://doi.org/10.1016/j.amjmed.2018.04.025
  74. Nardi, I., Reno, T., Yun, X.W., Sztain, T., Wang, J.M., Dai, H.F., Zheng, L., Shen, B.H., Kim, J., & Raz, D. (2018). Triptolide inhibits Wnt signaling in NSCLC through upregulation of multiple Wnt inhibitory factors via epigenetic modifications to Histone H3. International Journal of Cancer, 143(10), 2470-8. https://doi.org/10.1002/ijc.31756