Integrating both computer and laboratory studies, the Kaddis Lab is investigating important correlations between characteristics of the pancreas — home to the islet cells that produce insulin — and the onset, effect and outcomes of type 1 diabetes. Recent studies focus on samples of pancreata from nPOD. We are exploring the data that emerges for clues about the interactions among the structure and biochemistry of the organ, lifestyle and other external factors, and the causes and effects of disease.
Previous work has focused on:
Designing and implementing collaborative data sharing and analysis tools to expedite investigations
Using statistics and mathematical modeling to study diabetes
Studying childhood cancers using high throughput genomic data
Principal Investigator: John S. Kaddis, Ph.D.
An Assistant Professor in the Department of Diabetes & Cancer Discovery Science, John S. Kaddis conducts research that focuses on diabetes, systems biology, biostatistics and bioinformatics.