Synthetic Biopolymer Chemistry Core Publications

Shafat Ali, Yilan Zhang, Mian Zhou, Hongzhi Li, Weiwei Jin, Li Zheng, Xiaochun Yu, Jeremy Stark, and Binghui Shen, “Functional deficiency of DNA repair gene EXO5 in androgen induced genomic instability and prostate tumorigenesis”, Oncogene, accepted 2019

Awasthi S, Singhal SS, Singhal J, Nagaprashantha L, Li H, Yuan YC, Liu Z, Berz D, Igid H, Green WC, Tijani L, Tonk V, Rajan A, Awasthi Y, Singh SP. “Anticancer Activity of 2′-Hydroxyflavanone Towards Lung Cancer”, Oncotarget 2018 Nov 16;9(90):36202-36219. doi: 10.18632/oncotarget.26329.

Long Gu, Robert Lingeman, Fumiko Yakushijin, Emily Sun, Qi Cui, Jianfei Chao, Weidong Hu, Hongzhi Li, Robert Hickey, Jeremy Stark, Yate-Ching Yuan, Yuan Chen, Steven Vonderfecht, Timothy Synold, Yanhong Shi, Karen Reckamp, David Horne, and Linda Malkas, “The anti-cancer activity of a first-in-class small molecule targeting PCNA” Clin Cancer Res. 2018 Jul 2. pii: clincanres.0592.2018. doi: 10.1158/1078-0432.CCR-18-0592.

Liu SB, Dong HJ, Bao XB, Qiu QC, Li HZ, Shen HJ, Ding ZX, Wang C, Chu XL, Yu JQ, Tao T, Li Z, Tang XW, Chen SN, Wu DP, Li L, Xue SL. “Impact of FLT3-ITD length on prognosis of acute myeloid leukemia.” Haematologica. 2018 Aug 3. pii: haematol.2018.191809. doi: 10.3324/haematol.2018.191809   9.0

Zhang XH, Nam S, Wu J, Chen CH, Liu X, Li H, McKeithan T, Gong Q, Chan WC, Yin HH, Yuan YC, Pillai R, Querfeld C, Horne D, Chen Y, Rosen ST, “Multi-kinase inhibitor with anti-p38γ activity in cutaneous T cell lymphoma”, J Invest Dermatol. 2018 Jul 14. pii: S0022-202X(18)31967-5.

Lan Tian, Min-Sung Kim, Hongzhi Li, Jimin Wang, and Wei Yang "Structure of HIV-1 reverse transcriptase cleaving RNA in an RNA/DNA hybrid" , Proceedings of the National Academy of Sciences, vol 115, 507-512, 2018  

Krishna BM, Jana S, Singhal J, Horne D, Awasthi S, Salgia R, Singhal SS. Notch signaling in breast cancer: From pathway analysis to therapy. Cancer Lett. 2019 Oct 1;461:123-131. doi: 10.1016/j.canlet.2019.07.012. Epub 2019 Jul 18.

Michalak SE, Nam S, Kwon DM, Horne DA, Vanderwal CD.A Chlorine-Atom-Controlled Terminal-Epoxide-Initiated Bicyclization Cascade Enables a Synthesis of the Potent Cytotoxins Haterumaimides J and K. J Am Chem Soc. 2019 Jun 12;141(23):9202-9206.

Giannouli V, Lougiakis N, Kostakis IK, Pouli N, Marakos P, Skaltsounis AL, Horne DA, Nam S, Gioti K, Tenta R. Design and synthesis of new substituted pyrazolopyridines with potent antiproliferative activity. Med Chem. 2019 Feb 22. doi: 10.2174/1573406415666190222130225. [Epub ahead of print]

Singhal J, Chikara S, Horne D, Salgia R, Awasthi S, Singhal SS. RLIP inhibition suppresses breast-to-lung metastasis. Cancer Lett. 2019 Apr 10;447:24-32. doi: 10.1016/j.canlet.2019.01.023. Epub 2019 Jan 23.

Golfetto O, Wakefield DL, Cacao EE, Avery KN, Kenyon V, Jorand R, Tobin SJ, Biswas S, Gutierrez J, Clinton R, Ma Y, Horne DA, Williams JC, Jovanović-Talisman T. A Platform To Enhance Quantitative Single Molecule Localization Microscopy. J Am Chem Soc. 2018 Oct 10;140(40):12785-12797. doi: 10.1021/jacs.8b04939. Epub 2018 Sep 26.

Singhal J, Singhal P, Horne D, Salgia R, Awasthi S, Singhal SS. Metastasis of breast tumor cells to brain is suppressed by targeting RLIP alone and in combination with 2'-Hydroxyflavanone. Cancer Lett. 2018 Dec 1;438:144-153.

Zhang XH, Nam S, Wu J, Chen CH, Liu X, Li H, McKeithan T, Gong Q, Chan WC, Yin HH, Yuan YC, Pillai R, Querfeld C, Horne D, Chen Y, Rosen ST. Multi-Kinase Inhibitor with Anti-p38γ Activity in Cutaneous T-Cell Lymphoma. J Invest Dermatol. 2018 Nov;138(11):2377-2387. doi: 10.1016/j.jid.2018.04.030. Epub 2018 Jul 14.

Bzymek KP, Puckett JW, Zer C, Xie J, Ma Y, King JD, Goodstein LH, Avery KN, Colcher D, Singh G, Horne DA, Williams JC. Mechanically interlocked functionalization of monoclonal antibodies. Nat Commun. 2018 Apr 20;9(1):1580.

Chikara S, Nagaprashantha LD, Singhal J, Horne D, Awasthi S, Singhal SS. Oxidative stress and dietary phytochemicals: Role in cancer chemoprevention and treatment. Cancer Lett. 2018 Jan 28;413:122-134. doi: 10.1016/j.canlet.2017.11.002. Epub 2017 Nov 4. Review.