Mission

The City of Hope Alpha Clinic is committed to advancing the frontiers of cellular and gene therapy by providing access to innovative clinical trials for patients throughout California. Established in 2015 and renewed in 2022 with a five-year, $8 million grant from the California Institute for Regenerative Medicine (CIRM), the City of Hope Alpha Clinic is a proud member of a statewide Alpha Clinic Network focused on accelerating regenerative medicine.

This collaborative network works to:

Accelerate the development and delivery of advanced cell and gene therapies to Californians
Foster collaboration by sharing specialized expertise, resources, and best practices across partner institutions
Engage diverse communities through inclusive outreach and education initiatives
Provide comprehensive training and education for patients, researchers, and healthcare professionals

Together, we are shaping the future of medicine through innovation, collaboration, and compassionate care.

City of Hope's Alpha Clinic

City of Hope has a long-standing reputation for pioneering new therapies and operates an extensive network of satellite centers across Southern California, enabling the delivery of advanced treatments directly into communities. To meet the growing demand for cell and gene therapy manufacturing, the City of Hope Alpha Clinic collaborates with internal centers of excellence:

Laboratory for Cellular Medicine (LCM)
Cell and Gene Therapy Development & GMP Manufacturing Solutions
Office of IND Development and Regulatory Affairs
Translational Development Center (TDC)

Through partnerships with patient advocates and community stakeholders, the City of Hope Alpha Clinic is committed to meeting the needs of a diverse and decentralized patient population across its network.

The Alpha Clinic Network

The California Institute for Regenerative Medicine (CIRM) Alpha Clinics Network is a statewide consortium of nine leading medical institutions dedicated to advancing access to cell and gene therapies for all Californians. Funded by CIRM, this network includes Cedars-Sinai, Stanford University, UC Davis, UC Irvine, UC Los Angeles, UC San Diego, UC San Francisco, and the University of Southern California. Together, these institutions are committed to accelerating the development and delivery of regenerative medicine through clinical trials, patient care, and community engagement.

Learn more about the CIRM Alpha Clinics Network.

For more information about this program, please contact [email protected].

About Stem Cells

Stem cells, also known as progenitor cells, are cells that can produce specialized cells that are used to develop or repair organs.
There are two general types of stem cells: those of embryonic origin and those that arise from adult cells
In adults, stem cells can be found in many tissues and organs, including the bone marrow, skin, heart, brain and immune system.
Most therapies today are derived from adult stem cells.

Learn more about stem cells at the California Institute for Regenerative Medicine or International Society for Stem Cell Research websites.