Breast Cancer Clinical Trials and Research

Breast Cancer Clinical Trials and Research

At City of Hope, breast cancer clinicians and researchers collaborate extensively to develop and evaluate new therapies for better survival and quality-of-life outcomes. Our patients have access to a wide variety of clinical trials including new chemotherapy and targeted therapies, hormone therapies, novel surgical techniques, innovative radiation approaches and new prevention strategies.

Hormone Receptor Positive Metastatic Breast Cancer

NCT04305834: Principal investigator Mina S. Sedrak, M.D., M.S., is actively recruiting for a study on the benefits of abemacicilib monotherapy in treating patients aged 70 years or older with hormone receptor positive, HER2 negative breast cancer that has spread to other parts of the body.
 

Patient Enrollment Qualifications

  • Women 70 years of age or older
  • Measurable or nonmeasurable disease 
  • Life expectancy greater than six months

Theranostics

NCT03542695: IRB#18112 Principal investigator Veronica Jones, M.D., is recruiting for this early phase I pilot trial that studies how well 64Cu-DOTA-alendronate positron emission tomography imaging works in localizing and characterizing breast calcifications (small calcium deposits) in participants before undergoing mastectomy.
 

Patient Enrollment Qualifications

  • Women 18 years and older who are not pregnant
  • Evidence of calcifications on mammograms
Learn more about this promising study _______________________

 

NCT05376878: IRB#21050 Principal investigator Joanne E. Mortimer, M.D., F.A.C.P., F.A.S.C.O., is recruiting for this clinical trial examining an investigational scan (64Cu-DOTA-trastuzumab positron emission tomography/magnetic resonance imaging) in imaging patients with HER2+ breast cancer that has spread to the brain (brain metastasis.
 

Patient Enrollment Qualifications

  • Men and women 18 years and older
  • Women with metastatic HER2 positive breast cancer and brain metastases
Learn more about this promising study

 

To refer a patient to one of our clinical trials, please call 626-218-1133. Learn more about City of Hope's clinical trials.