Proteasome inhibition promotes Foxn1 expression in thymic epithelial cells and induces thymic regeneration in mice. Genah S, Pellegrino M, Giansanti M, Mancusi A, Taviani A, Cardinale A, Rosichini M, Flamini S, Catanoso ML, Giorda E, Volpe G, Piccione M, Nazio F, Dudakov JA, van den Brink MRM, de Billy E, Locatelli F, Velardi E.Cell Death Differ. 2026 Mar 26. doi: 10.1038/s41418-026-01724-7. Online ahead of print. PMID: 41888548
Author Correction: Age-related epithelial defects limit thymic function and regeneration. Kousa AI, Jahn L, Zhao K, Flores AE, Acenas D 2nd, Lederer E, Argyropoulos KV, Lemarquis AL, Granadier D, Cooper K, D'Andrea M, Sheridan JM, Tsai J, Sikkema L, Lazrak A, Nichols K, Lee N, Ghale R, Malard F, Andrlova H, Velardi E, Youssef S, Burgos da Silva M, Docampo M, Sharma R, Mazutis L, Wimmer VC, Rogers KL, DeWolf S, Gipson B, Gomes ALC, Setty M, Pe'er D, Hale L, Manley NR, Gray DHD, van den Brink MRM, Dudakov JA. Nat Immunol. 2026 May;27(5):1082. doi: 10.1038/s41590-026-02489-4. PMID: 41826733 Free PMC article. No abstract available.
Differential effects of two common GVHD prophylaxis regimens on the gut microbiome: Results from the BMT CTN 1801 study. Wirbel J, Saber W, Martens MJ, Peled JU, Andermann TM, Fei T, Brooks EF, Doyle B, Pincus NB, Jenq RR, Bar M, Bolaños-Meade J, Bratrude B, Chhabra S, Choi SW, Clark W, Das S, Elmariah H, Gooptu M, Holtan SG, Jones RJ, Levine JE, Logan BR, Al Malki MM, Murthy HS, Rashidi A, Rezvani AR, Riches ML, Runaas L, Sandhu K, Spahn A, Sung AD, van den Brink MRM, Horowitz MM, Hamadani M, Kean LS, Perales MA, Bhatt AS. bioRxiv [Preprint]. 2026 Feb 19:2026.02.19.706769. doi: 10.64898/2026.02.19.706769.PMID: 41756883 Free PMC article. Preprint.
The intestinal microbiota as a key modulator of acute graft-versus-host disease. Paredes J, Schmiester M, Jenq R, van den Brink MRM. Nat Rev Cancer. 2026 May;26(5):328-350. doi: 10.1038/s41568-026-00910-6. Epub 2026 Feb 26. PMID: 41748753 Review.
IL-7: a potential next-generation adjuvant for immune cell therapies. Hotchkiss RS, DiPersio JF, Yee C, Pachynski RK, van den Brink MRM. Front Immunol. 2026 Jan 2;16:1736931. doi: 10.3389/fimmu.2025.1736931. eCollection 2025. PMID: 41550947 Free PMC article. Review.
Enterococcus faecalis induces MHC-II expression by the intestinal epithelium during murine graft-versus-host disease. Nguyen CL, Funes J, Ghale R, Duong N, Victor K, Gipson B, Zhang ZJ, Dai A, Li R, Armijo G, Huang A, Martinez M, Chen Y, Ghazarian D, Docampo M, Pathak K, Pirrotte P, Markey KA, Peled JU, Paredes J, Burgos da Silva M, van den Brink MRM. Blood. 2026 Mar 26;147(13):1485-1497. doi: 10.1182/blood.2024028248. PMID: 41460962 Free PMC article.
A High-Fiber, Plant-Based Diet in Myeloma Precursor Disorders: Results from the NUTRIVENTION Clinical Trial and Preclinical Vk*MYC Model. Shah UA, Cogrossi LL, Garcés JJ, Policastro A, Castro F, Derkach A, Fei T, DeWolf S, Grioni M, Sisti S, Blaslov J, Adintori PA, Hosszu KK, McAvoy D, Baichoo M, Cross JR, Paredes J, Anuraj A, Raj SS, Pohl C, Zordan P, Zinsmeyer V, Jesus Faustino Ramos RJ, Lorenzoni M, Gipson B, Maclachlan KH, Gradissimo A, Boiocchi L, Aleynick N, Marchigiani C, Pagani S, Salehi E, Koche RP, Chaligne R, Block T, Korde N, Tan CR, Hultcrantz M, Hassoun H, Shah GL, Scordo M, Lahoud OB, Chung DJ, Landau HJ, Peled JU, Clementi N, Chesi M, Bergsagel PL, Mailankody S, Pollak MN, D'Souza A, Landgren O, Chimonas S, Giralt SA, Usmani SZ, Iyengar NM, Lesokhin AM, van den Brink MRM, Bellone M. Cancer Discov. 2026 Apr 1;16(4):697-720. doi: 10.1158/2159-8290.CD-25-1101. PMID: 41342739 Free PMC article.
Galectin-3 is a Nanotherapeutic Target in Graft-versus-Host Disease Mediated Kidney Injury. Panagiotakopoulou M, Sullivan AN, Argyropoulos KV, Kousa AI, Nunez J, Pierpont K, Ruiz S, Grabarnik E, Gipson B, Ghale R, Seshan S, Muthukumar T, Hanash AM, van den Brink MRM, Jaimes EA, Heller DA. bioRxiv [Preprint]. 2025 Nov 19:2025.11.19.688972. doi: 10.1101/2025.11.19.688972.PMID: 41332663 Free PMC article. Preprint.
Leucine Zipper-based Cell Sorting for Purification of Dual-vector-transduced Cells. Su K, Wang B, Rajagopalan A, Chen S, Boardman AP, van den Brink MRM, James SE. J Vis Exp. 2025 Oct 24;(224):10.3791/68628. doi: 10.3791/68628. PMID: 41212833 Free PMC article.
Cancer Survival at a Comprehensive Cancer Center Compared with Surveillance, Epidemiology, and End Results (SEER) Estimates. Salgia R, Alvarnas J, Trisal V, Vanderplas A, Li X, Arias-Romero J, Fricke J, Frankel P, Mambetsariev I, Rice H, Levine H, van den Brink MRM. medRxiv [Preprint]. 2025 Sep 8:2025.09.05.25335204. doi: 10.1101/2025.09.05.25335204. PMID: 40963747 Free PMC article. Preprint.