Lab Publications

 
  • Liu T, Lam V, Thieme E, Sun D, Wang X, Xu F, Wang L, Danilova OV, Xia Z, Tyner JW, Kurtz SE and Danilov AV. 2021. Pharmacologic targeting Mcl-1 induces mitochondrial dysfunction and apoptosis in B-cell lymphoma cells in TP53- and BAX-dependent manner. Clin Cancer Res.
  • Gordon MJ, Kaempf A, Sitlinger A, Shouse G, Mei M, Brander DM, …, Shadman M, Park B and Danilov AV. 2021. The chronic lymphocytic leukemia comorbidity index (CLL-CI): a three-factor comorbidity model. Clin Cancer Res. DOI:10.1158/1078-0432.CCR-20-3993
  • Kittai AS, Best S, Thurlow B, Lam V, Hashiguchi T, Goodyear S, Persky DO, Okada C, Park B, Spurgeon S and Danilov AV. 2021. Entospletinib and obinutuzumab in patients with relapsed/refractory CLL and B-cell malignancies. Haematologica. doi: 10.3324/haematol.2020.270298.
  • Best S, Lam V, Liu T, Bruss N, Kittai A, Danilova OV, Murray S, Berger A, Pennock ND, Lind EF and Danilov AV. 2021. Immunomodulatory effects of pevonedistat, a Nedd8-activating enzyme inhibitor, in CLL. Leukemia. 35(1): 156-168.
  • Danilov AV, Persky DO. 2021. Incorporating acalabrutinib, a next-generation selective BTK inhibitor, into clinical practice for the treatment of hematologic malignancies. 2020. Br J Haematol. 193(1):15-25.
  • Evens AM, Danilov AV, …, Olszewski AJ and Alderuccio JP. 2021. Burkitt Lymphoma in the Modern Era: Real World Outcomes and Prognostication Across 30 US Cancer Centers. Blood. 137(3); 374-386.
  • Gordon MJ, Huang J, Chan RJ, Bhargava P and Danilov AV. 2021. Medical comorbidities in patients with chronic lymphocytic leukemia treated with idelalisib: analysis of two large randomized clinical trials. British J Haemtol. 192(4): 720-728.
  • Danilov AV, Spurgeon SE, Siddiqi T, Quinson AM, Maier D, Smith D and Brown JR. 2021. A Phase Ib, open label, dose escalation trial of the anti-CD37 monoclonal antibody, BI836826, in combination with ibrutinib in patients with relapsed/refractory CLL. Invest New Drugs. doi: 10.1007/s10637-020-01056-4
  • Danilov AV, Herbaux C, Walter H, Hillmen P, Rule S, Kio EA, Karlin L, Dyer MJ, Mitra S, Yi PC, Humeniuk R, Huang X, Zhou Z, Bhargava P, Jurgensmeier JM and Fegan C. 2020. Phase 1b study of tirabrutinib alone or in combination with idelalisib or entospletinib in previously treated CLL. Clinical Cancer Research. 26 (12): 2810-2818.
  • Kittai AS Gordon MJ, Mian A, Fitzgerald L, Bishop K, Stephens DM, Nagle SJ, Hill BT and Danilov AV. 2020. Comorbidities predict inferior survival in patients receiving chimeric antigen receptor T-cell therapy for DLBCL: A multicenter analysis. Biology of Blood and Marrow Transplantation. In press.
  • Eide CA, Kurtz SE, Kaempf A, Long N, Agarwal A, Tognon CE, Mori M, Druker BJ, Chang BH, Danilov AV and Tyner JW. 2020. Simultaneous kinase inhibition with ibrutinib and BCL2 inhibition with venetoclax offers a therapeutic strategy for acute myeloid leukemia. Nature Leukemia. doi: 10.1038/s41375-020-0764-6.
  • Best SR, Hashiguchi T, Kittai A, Bruss N, Paiva C, Okada C, Liu T, Berger A and Danilov AV. 2019. Targeting ubiquitin-activating enzyme induces ER stress-mediated apoptosis in B-cell lymphoma cells. Blood Advances. 3(1): 51-62.
  • Hashiguchi T, Bruss N, Best S, Lam V, Danilova OV, Paiva C, Wolf J, Gilbert E, Okada C, Kaur P, Drew L, Cidado J, Hurlin P and Danilov AV. 2019. Cyclin-dependent kinase-9 is a therapeutic target in MYC-expressing diffuse large B-cell lymphoma. Molecular Cancer Therapeutics. 18(9): 1520-1532.
  • Nechiporuk T, Kurtz SE, Nikolova O, Liu T, Jones CL, D’Alessandro A, Culp-Hill R, d’Almeida A, Joshi SK, Rosenberg M, Tognon CE, Danilov AV, Druker BJ, Chang BH, McWeeney SK and Tyner JW. 2019. The TP53 apoptotic network is a primary mediator of resistance to BCL2 inhibition in AML cells. Cancer Discovery. 9 (7): 910-925.
  • Gordon M, Churnetski M, Alqahtani H, Rivera X, Kittai A, Amrock SM, James S, Hoff S, Manda S, Spurgeon SE, Choi M, Cohen JB, Persky D and Danilov AV. 2018. Comorbidities predict inferior outcomes in chronic lymphocytic leukemia treated with ibrutinib. Cancer. 124(15): 3192-3200.