DNA/RNA Publications

Su YL, Wang X, Mann M, Adamus TP, Wang D, Moreira DF, Zhang Z, Ouyang C, He X, Zhang B, Swiderski PM, Forman SJ, Baltimore D, Li L, Marcucci G0, Boldin M, Kortylewski M. Myeloid Cell-Targeted miR-146a Mimic Inhibits NF-kB-Driven Inflammation and Leukemia Progression in Vivo. Blood. 2019 Dec 5. pii: blood.2019002045. doi: 10.1182/blood.2019002045. [Epub ahead of print] 

Nuzzo, Silvia & Catuogno, Silvia & Capuozzo, Maria & Fiorelli, Alfonso & Swiderski, Piotr & Boccella, Serena & F, de & Esposito, Carla. (2019). “Axl-Targeted Delivery of the Oncosuppressor miR-137 in Non-small-Cell Lung Cancer”. Molecular Therapy - Nucleic Acids. 17. 10.1016/j.omtn.2019.06.002. Molecular Therapy - Nucleic Acids 

Yu-Lin Su, Xiuli Wang, Mati Mann, Tomasz Adamus, Dayson Moreira, Zhuoran Zhang, Ching Ouyang, Piotr Swiderski, David Baltimore, Stephen Forman, Ling Li, Marcin Kortylewski “Myeloid Cell-Selective miR-146a Mimic Inhibits NF-kB-Driven Inflammation and Tumorigenic Effects in Vivo” Blood 

Dayson Moreira, Tomasz Adamus, Xingli Zhao, Yu-Lin Su, Zhuoran Zhang, Seok White, Piotr Swiderski, Xin Lu, Ronald DePinho, Sumanta Pal, and Marcin Kortylewski Manuscript Number: CD-18-0429 , ”STAT3 inhibition combined with CpG immunostimulation activates antitumor immunity to eradicate genetically distinct castration-resistant prostate cancers” Published OnlineFirst October 18, 2018,doi: 10.1158/1078-0432.CCR-18-1277, Clinical Cancer Research, 

L.X. Nguyen , L. Li , D Zhao , B. Kumar , H. Wu , A. Lin ,  F. Pellicano ,  L. Hopcroft ,  Yu-Lin Su , M. Copland , T.L. Holyoake ,  C. Kuo ,  R. Bhatia ,  D. Snyder ,  H. Ali ,  A. Stein ,  C. Brewer , H. Wang , T.  McDonald , Piotr Swiderski ,  E. Troadec ,  Ching-Cheng Chen ,  A. Dorrance ,  V. Pullarkat ,  Yate-Ching Yuan , D. Perrotti ,  N. Carlesso ,  Stephen J. Forman ,  M. Kortylewski , Ya-Huei Kuo ,  G. Marcucci, “Bone Marrow Niche Trafficking of miR-126 Controls Self-Renewal of Leukemia Stem Cells in Chronic Myelogenous Leukemia”, Nat Med 2018 May 5;24(4):450-462. Epub 2018 Mar 5. 

Yijie Wang, Jan Hoinka, Piotr Swiderski and Teresa Przytycka, “AptaBlocks: Accelerating the Design of RNA-based Drug Delivery Systems” RECOMB 2018, accepted to Cell Systems   

Xingli Zhao, Zhuoran Zhang, Dayson Moreira, Yu-Lin Su, Haejung Won, Tomasz Adamus, Zhenyuan Dong, Yong Liang, Hongwei Yin, Piotr Swiderski, Raju Pillai, Larry Kwak, Stephen Forman, and Marcin Kortylewski, "B-cell lymphoma immunotherapy using TLR9-targeted oligonucleotide STAT3 inhibitors" by Molecular Therapy.  2018 [Paper #MTJ-17-1760R2 

Yu-lin Su , Zhuoran Zhang, Piotr Swiderski, Defu Zeng  Guido Marcucci, Mark Boldin, Marcin Kortylewski, “Targeted Delivery of miR-146a Mimic Oligonucleotides as a Potential Therapeutic Approach to Modulate NF-kB Signaling in Myeloid Leukemia and Myeloproliferative Diseases”, Experimental Hematology 64 (2018) S41–S51 

Sorah Yoon, Kai-Wen Huang, Vikash Reebye, Duncan Spalding, Teresa M. Przytycka, Yijie Wang,  Piotr Swiderski, Lin Li, Brian Armstrong, Isabella Reccia, Dimitris Zacharoulis, Konstantinos Dimas, Tomokazu Kusano, John Shively, Nagy Habib and John J. Rossi, “Aptamer drug conjugates (ApDCs) of active metabolites of nucleoside analogues and cytotoxic agents inhibit pancreatic tumorcell growth” Article (PDF Available) in Molecular Therapy - Nucleic Acids · December 2016 DOI: 10.1016/j.omtn.2016.11.008 

Sorah Yoon, Kai-Wen Huang,Vikash Reebye, Paul Mintz, Yu-Wen Tien, Hong-Shiee Lai, Pål Sætrom, Isabella Reccia, Piotr Swiderski, Brian Armstrong,Agnieszka Jozwiak,Duncan Spalding, Long Jiao, Nagy Habib and John J Rossi, “Targeted Delivery of C/EBPα -saRNA by Pancreatic Ductal Adenocarcinoma (PDAC)-specific RNA aptamers Inhibits Tumor Growth in Vivo” Accepted manuscript © 2016 The American Society of Gene & Cell Therapy.  

Andrew R Chin, Miranda Y Fong, George Somlo, Jun Wu, Piotr Swiderski,  Xiwei Wu, Emily Wang “Cross-kingdom inhibition of breast cancer growth by plant miR159” Article in Cell Research 26(2) · January 2016 DOI: 10.1038/cr.2016.13 

Qifang Zhang, Dewan Md Sakib Hossain, Priyanka Duttagupta, Dayson Moreira, Xingli Zhao, Haejung Won, Ralf Buettner, Sergey Nechaev, Marcin Majka, Bin Zhang,Qi Cai, Piotr Swiderski, Ya-Huei Kuo, Stephen Forman, Guido Marcucci, and Marcin Kortylewski,  “Serum-resistant CpG-STAT3 decoy for targeting survival and immune checkpoint signaling in acute myeloid leukemia” Blood. 2016 Mar 31; 127(13): 1687–1700. Prepublished online 2016 Jan 21. doi:  10.1182/blood-2015-08-665604, PMCID: PMC4817311 

Hossain DM, Moreira D, Zhang Q, Nechaev S, Swiderski P, Kortylewski M. “TLR9-Targeted SiRNA Delivery In Vivo” Methods Mol Biol. 2016;1364:183-96. doi: 10.1007/978-1-4939-3112-5_15.   

John J. Rossi, Sorah Yoon, Nagy A. Habib, Paul J Mintz, Isabella Reccia, Kai-Wen Huang, Piotr Swiderski, Hong-Shiee Lai, Agnieszka Jozwiak, Brian Armstrong, Duncan Spalding, Long R Jiao, Vikash Reebye, Yu-Wen Tien, "C/EBPα -saRNA delivery by Pancreatic Ductal Adenocarcinoma (PDAC)-specific RNA aptamers inhibits tumor growth in vivo" PNAS, The manuscript has been assigned tracking number 2015-11598. 

Miranda Y. Fong, Weiying Zhou, Liang Liu, Aileen Y. Alontaga, Manasa Chandra, Jonathan Ashby, Amy Chow, Sean Timothy Francis O’Connor, Shasha Li, Andrew R. Chin, George Somlo, Melanie Palomares, Zhuo Li, Jacob R. Tremblay, Akihiro Tsuyada, Guoqiang Sun, Michael A. Reid, Xiwei Wu, Piotr Swiderski, Xiubao Ren, Yanhong Shi, Mei Kong, Wenwan Zhong,Yuan Chen and Shizhen Emily Wang, “Breast cancer-secreted miR-122 reprograms glucose metabolism in premetastatic niche to promote metastasis” Nature Cell Biology 

Esposito Cl, Cerchia L, Catuogno S, de Vita G, Dassie Jp, Santamaria G, Swiderski P, Condorelli G, Giangrande Ph, de Franciscis V, “Multifunctional aptamer-miRNA conjugates for targeted cancer therapy”  Molecular Therapy 01/2014” 

Andreas Herrmann, Saul J. Priceman, Piotr Swiderski, Maciej Kujawski, Hong Xin, Gregory A. Cherryholmes, Wang Zhang, Chunyan Zhang, Christoph Lahtz, Claudia Kowolik, Steve J. Forman, Marcin Kortylewski and Hua Yu, “CTLA4 aptamer delivers STAT3 siRNA to tumor-associated and malignant T cells”,  J. Clin. Invest. 2014; 124(7):2977–2987, 

Andreas Herrmann, Gregory Cherryholmes, Anne Schroeder, Jillian Phallen, Darya Alizadeh, Hong Xin, Tianyi Wang, Heehyoung Lee, Christoph Lahtz, Piotr Swiderski, Brian Armstrong, Claudia Kowolik, Gary L Gallia, Michael Lim, Christine E Brown, Behnam Badie, Stephen J Forman, Marcin Kortylewski, Richard Jove, Hua Yu “TLR9 is Critical for Glioma Stem Cell Maintenance and Targeting.”  Cancer Research 07/2014; DOI: 10.1158/0008-5472.CAN-14-1151 

Hossain DM, Dos Santos C, Zhang Q, Kozlowska A, Liu H, Gao C, Moreira D, Swiderski P, Jozwiak A, Kline J, Forman S, Bhatia R, Kuo YH, Kortylewski M, “Leukemia cell-targeted STAT3 silencing and TLR9 triggering generate systemic antitumor immunity.”Blood, 02 January 2014, vol./is. 123/1(15-25), 0006-4971, 02 January 2014