Integrative Genomics Publications

ZM Z, SE Y, KE H, SM L, YC Y, J N, Z L, C W, RM J, X W et al: - CCNE1 amplification is associated with poor prognosis in patients with triple negative breast cancer. BMC Cancer 2019, 19(1):019-5290.


YC D, L S, C W, S W, J M, Y Y, SL N: - Molecular subtypes of triple-negative breast cancer in women of different race and ethnicity. Oncotarget 2019, 10(2):198-208.


TP S, JB T, JN W, K P, FL W, H Q, J W, X W, M M, R P et al: - Association between Clonal Hematopoiesis and Late Nonrelapse Mortality after Autologous Hematopoietic Cell Transplantation. LID - S1083-8791(19)30527-0 [pii] LID - 10.1016/j.bbmt.2019.08.013 [doi]. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2019, 22(19):30527-30520.


Song A Fau - Dai W, Dai W Fau - Jang MJ, Jang Mj Fau - Medrano L, Medrano L Fau - Li Z, Li Z Fau - Zhao H, Zhao H Fau - Shao M, Shao M Fau - Tan J, Tan J Fau - Li A, Li A Fau - Ning T, Ning T Fau - Miller MM et al: - Low- and high-thermogenic brown adipocyte subpopulations coexist in murine adipose tissue. LID - 10.1172/JCI129167 [doi] LID - 129167 [pii]The Journal of clinical investigation 2019, 1(129167).


S Y, X W, B A, N H, JJ R: - An RNA Aptamer Targeting the Receptor Tyrosine Kinase PDGFRalpha Induces Anti-tumor Effects through STAT3 and p53 in Glioblastoma. Mol Ther Nucleic Acids 2019, 14:131-141.


R B, C M, X W, JF S, H L, LG M, ST R: - Leflunomide Synergizes with Gemcitabine in Growth Inhibition of PC Cells and Impairs c-Myc Signaling through PIM Kinase Targeting. Mol Ther Oncolytics 2019, 14:149-158.


R B, C M, E C, E T, EG G, D V, J K, H L, JJ K, A C et al: - Leflunomide regulates c-Myc expression in myeloma cells through PIM targeting. Blood Adv 2019, 3(7):1027-1032.


N K, L B, G C, T Y, D N, YZ W, JS P, C W, J W, X W et al: - Molecular Mechanisms of Polybrominated Diphenyl Ethers (BDE-47, BDE-100, and BDE-153) in Human Breast Cancer Cells and Patient-Derived Xenografts. Toxicol Sci 2019, 169(2):380-398.


Mutsvunguma LZ, Rodriguez E, Escalante GM, Muniraju M, Williams JC, Warden C, Qin H, Wang J, Wu X, Barasa A et al: Identification of multiple potent neutralizing and non-neutralizing antibodies against Epstein-Barr virus gp350 protein with potential for clinical application and as reagents for mapping immunodominant epitopes. Virology 2019, 536:1-15.


M S, C D, X R, W Y, M C, D P, X W, L Y, L L, X R et al: - Chemotherapy-Induced Extracellular Vesicle miRNAs Promote Breast Cancer Stemness by Targeting ONECUT2Cancer Res 2019, 79(14):3608-3621.


LZ M, E R, GM E, M M, JC W, C W, H Q, J W, X W, A B et al: - Identification of multiple potent neutralizing and non-neutralizing antibodies against Epstein-Barr virus gp350 protein with potential for clinical application and as reagents for mapping immunodominant epitopes. Virology 2019, 536:1-15.


K Z, J W, J W, F L, X L, L Y, YR L, L S, YS Y, P C et al: - LKB1 deficiency promotes proliferation and invasion of glioblastoma through activation of mTOR and focal adhesion kinase signaling pathways. Am J Cancer Res 2019, 9(8):1650-1663.


JN W, I-O, SL N, A A, S T, C R, A M, I-O, M R, B N et al: - Pathogenic and likely pathogenic variants in PALB2, CHEK2, and other known breast cancer susceptibility genes among 1054 BRCA-negative Hispanics with breast cancer. Cancer 2019, 125(16):2829-2836.


JH Y, AH C, AX L, H Q, S C, ST T, P C, BW K, D S, R L et al: - Identification of Tissue-Specific DNA Methylation Signatures for Thyroid Nodule Diagnostics. Clin Cancer Res 2019, 25(2):544-551.


H H, H W, K Z, T W, BS Z, M S, Z C, X D, G X, F A et al: - Histone H3 trimethylation at lysine 36 guides m(6)A RNA modification co-transcriptionally. Nature 2019, 567(7748):414-419.


Z Z, J F, A M, K L, D LP, X W, J L, C M, RP SA, SL N et al: - SNPs in inflammatory genes CCL11, CCL4 and MEFV in a fibromyalgia family study. PLoS One 2018, 13(6).


Z L, B L, W J, X W, M Z, VZ L, A G, Z S, Id O, L Z et al: - hDNA2 nuclease/helicase promotes centromeric DNA replication and genome stability. LID - e96729 [pii] LID - 10.15252/embj.201796729 [doi]Embo J 2018, 37(14):17.


X Y, K Z, J W, RP P, L Y, M B, J W, J W, IK N, M G et al: - Targeting USP22 Suppresses Tumorigenicity and Enhances Cisplatin Sensitivity Through ALDH1A3 Downregulation in Cancer-Initiating Cells from Lung Adenocarcinoma. Mol Cancer Res 2018, 16(7):1161-1171.


X L, M C, M P, X W, A L, W Y, MY F, WC C, SE W, Id O: - Metastatic breast cancer cells overexpress and secrete miR-218 to regulate type I collagen deposition by osteoblasts. Breast Cancer Res 2018, 20(1):018-1059.


W Y, X W, W Z, MY F, M C, J L, X L, CH C, O F, DP P et al: - Cancer-cell-secreted exosomal miR-105 promotes tumour growth through the MYC-dependent metabolic reprogramming of stromal cells. Nat Cell Biol 2018, 20(5):597-609.


V P, T M, A N, I M, B M, X W, A H, EE V, DL W, R S: - Exosomal miRNAs species in the blood of small cell and non-small cell lung cancer patients. Oncotarget 2018, 9(28):19793-19806.


TP S, SL N, B N, M N-S, I S, C R, K B, A A, K Y, S S et al: - The spectrum of genetic variants in hereditary pancreatic cancer includes Fanconi anemia genes. Fam Cancer 2018, 17(2):235-245.


SF C, Z L, S C, TH D, J L, X W, H Q, J W, Y F, YC Y: - Identification of core aberrantly expressed microRNAs in serous ovarian carcinoma. Oncotarget 2018, 9(29):20451-20466.


S L, S A, X D, S L, J D, C L, H D, M Z, L Z, L Y et al: - JMJD1B Demethylates H4R3me2s and H3K9me2 to Facilitate Gene Expression for Development of Hematopoietic Stem and Progenitor Cells. Cell Rep 2018, 23(2):389-403.


S B, Z V, M L, J W, AD R, J S-S: - Frequent monoallelic or skewed expression for developmental genes in CNS-derived cells and evidence for balancing selection. Proc Natl Acad Sci U S A 2018, 115(44):E10379-E10386.


S A, J T, J S, AD R, S Y, X W, S S, C W, Z L, J W et al: - Rlip depletion prevents spontaneous neoplasia in TP53 null mice. Proc Natl Acad Sci U S A 2018, 115(15):3918-3923.


LD N, J S, H L, C W, X L, D H, S A, R S, SS S: - 2'-Hydroxyflavanone effectively targets RLIP76-mediated drug transport and regulates critical signaling networks in breast cancer. Oncotarget 2018, 9(26):18053-18068.


L L, E T, X C, J C, J K, Q Q, G S, G S, Y H, CD W et al: - GFAP Mutations in Astrocytes Impair Oligodendrocyte Progenitor Proliferation and Myelination in an hiPSC Model of Alexander Disease. Cell Stem Cell 2018, 23(2):239-251.


K Z, Id O, J W, L Y, YC Y, TR T, J W, X Y, M B, R P et al: - Targeting histone methyltransferase G9a inhibits growth and Wnt signaling pathway by epigenetically regulating HP1alpha and APC2 gene expression in non-small cell lung cancer. Mol Cancer 2018, 17(1):018-0896.


K P, N K, C L, PY H, D N, L Y, L Y, C W, X W, R P et al: - ERalpha-mediated cell cycle progression is an important requisite for CDK4/6 inhibitor response in HR+ breast cancer. Oncotarget 2018, 9(45):27736-27751.


J S, X H, Y Z, Z D, H D, Y F, J D, H W, X W, L Z et al: - SIRT1 Activation Disrupts Maintenance of Myelodysplastic Syndrome Stem and Progenitor Cells by Restoring TET2 Function. Cell Stem Cell 2018, 23(3):355-369


J L, A G, X W, RJ L, Q L: - Alternative RNA Splicing Associated With Mammalian Neuronal Differentiation. Cereb Cortex 2018, 28(8):2810-2816.


C Q, S L, PL M, SA C, DA G, G H, X W, SH K, S S, KJ F et al: - Primary T Cells from Cutaneous T-cell Lymphoma Skin Explants Display an Exhausted Immune Checkpoint Profile. Cancer Immunol Res 2018, 6(8):900-909.


A G, R Q, K M, J L, X W, H Z, H F, N D, M J, JK Y et al: - KIF20A/MKLP2 regulates the division modes of neural progenitor cells during cortical development. Nat Commun 2018, 9(1):018-05152.