Publication Highlights

  • Budde, L.E., Sehn, L.H., Matasar, M., Schuster, S.J., Assouline, S., Giri, P., Kuruvilla, J., Canales, M., Dietrich, S., Fay, K., Ku, M., Nastoupil, L., Cheah, C.Y., Wei, M.C., Yin, S., Li, C.C., Huang, H., Kwan, A., Penuel, E., & Bartlett, N.L. Safety and efficacy of mosunetuzumab, a bispecific antibody, in patients with relapsed or refractory follicular lymphoma: a single-arm, multicentre, phase 2 study. Lancet Oncol. 2022;23(8):1055-1065. PMID: 35803286.
  • Mei, M.G., Lee, H.J., Palmer, J.M., Chen, R., Tsai, N.C., Chen, L., McBride, K., Smith, D.L., Melgar, I., Song, J.Y., Bonjoc, K.J., Armenian, S., Nwangwu, M., Lee, P.P., Zain, J., Nikolaenko, L., Popplewell, L., Nademanee, A., Chaudhry, A., Rosen, S., Kwak, L., Forman, S.J., & Herrera, A.F. Response-adapted anti-PD-1-based salvage therapy for Hodgkin lymphoma with nivolumab alone or in combination with ICE. Blood. 2022;139(25):3605-3616. PMID: 35316328; PMCID: PMC9227101.
  • Liu, T., Lam, V., Thieme, E., Sun, D., Wang, X., Xu, F., Wang, L., Danilova, O.V., Xia, Z., Tyner, J.W., Kurtz, S.E., & Danilov, A.V. Pharmacologic Targeting of Mcl-1 Induces Mitochondrial Dysfunction and Apoptosis in B-Cell Lymphoma Cells in a TP53- and BAX-Dependent Manner. Clin Cancer Res. 2021;27(17):4910-4922. PMID: 34233959; PMCID: PMC8416922.
  • Querfeld, C., Thompson, J.A., Taylor, M.H., DeSimone, J.A., Zain, J.M., Shustov, A.R., Johns, C., McCann, S., Lin, G.H.Y., Petrova, P.S., Uger, R.A., Molloy, N., Shou, Y., & Akilov, O.E. Intralesional TTI-621, a novel biologic targeting the innate immune checkpoint CD47, in patients with relapsed or refractory mycosis fungoides or Sézary syndrome: a multicentre, phase 1 study. Lancet Haematol. 2021 Nov;8(11):e808-e817. PMID: 34627593.
  • Herrera, A.F., Chen, L., Nieto, Y., Holmberg, L., Johnston, P., Mei, M., Popplewell, L., Armenian, S., Cao, T., Farol, F., Sahebi, F., Spielberger, R., Chen, R., Nademanee, A., Puverel, S., Nwangwu, M., Lee, P., Song, J., Skarbnik, A., Kennedy, N., Peters, L., Rosen, S.T., Kwak, L.W., Forman, S.J., & Feldman, T. Brentuximab vedotin plus nivolumab after autologous haematopoietic stem-cell transplantation for patients with high-risk classic Hodgkin lymphoma: a multicentre, phase 2 trial. Lancet Haematol. 2022 (In press).
  • Budde, L.E., Assouline, S., Sehn, L.H., Schuster, S.J., Yoon, S.S., Yoon, D.H., Matasar, M.J., Bosch, F., Kim, W.S., Nastoupil, L.J., Flinn, I.W., Shadman, M., Diefenbach, C., O'Hear, C., Huang, H., Kwan, A., Li, C.C., Piccione, E.C., Wei, M.C., Yin, S., & Bartlett, N.L. Single-Agent Mosunetuzumab Shows Durable Complete Responses in Patients With Relapsed or Refractory B-Cell Lymphomas: Phase I Dose-Escalation Study. J Clin Oncol. 2022;40(5):481-491. PMID: 34914545; PMCID: PMC8824395.
  • Yi, S., Yan, Y., Jin, M., Bhattacharya, S., Wang, Y., Wu, Y., Yang, L., Gine, E., Clot, G., Chen, L., Yu, Y., Zou, D., Wang, J., Phan, A.T., Cui, R., Li, F., Sun, Q., Zhai, Q., Wang, T., Yu, Z., Liu, L., Liu, W., Lyv, R., Sui, W., Huang, W., Xiong, W., Wang, H., Li, C., Xiao, Z., Hao, M., Wang, J., Cheng, T., Bea, S., Herrera, A.F., Danilov, A., Campo, E., Ngo, V.N., Qiu, L., & Wang, L. Genomic and transcriptomic profiling reveals distinct molecular subsets associated with outcomes in mantle cell lymphoma. J Clin Invest. 2022;132(3):e153283. PMID: 34882582; PMCID: PMC8803323.
  • Amador, C., Bouska, A., Wright, G., Weisenburger, D.D., Feldman, A.L., Greiner, T.C., Lone, W., Heavican, T., Smith, L., Pileri, S., Tabanelli, V., Ott, G., Rosenwald, A., Savage, K.J., Slack, G., Kim, W.S., Hyeh, Y., Li, Y., Dong, G., Song, J., Ondrejka, S., Cook, J.R., Barrionuevo, C., Lim, S.T., Ong, C.K., Chapman, J., Inghirami, G., Raess, P.W., Bhagavathi, S., Gould, C., Blombery, P., Jaffe, E., Morris, S.W., Rimsza, L.M., Vose, J.M., Staudt, L., Chan, W.C.*, & Iqbal, J.* Gene Expression Signatures for the Accurate Diagnosis of Peripheral T-Cell Lymphoma Entities in the Routine Clinical Practice. J Clin Oncol. 2022 Jul 15:JCO2102707. PMID: 35839444. *co-corresponding authors
  • Strati, P., Coleman, M., Champion, R., Ma, S., Patti, C., Levy, M.Y., Lossos, I.S., Geethakumari, P.R., Lam, S., Calvo, R., Higgins, K., & Budde, L.E. A phase 2, multicentre, open-label trial (ACE-LY-003) of acalabrutinib in patients with relapsed or refractory marginal zone lymphoma. Br J Haematol. 2022;199(1):76-85. PMID: 35861370.
  • Kambhampati, S., Saumoy, M., Schneider, Y., Serrao, S., Solaimani, P., Budde, L.E., Mei, M.G., Popplewell, L., Siddiqi, T., Zain, J., Forman, S.J., Kwak, L.W., Rosen, S.T., Danilov, A.V., Herrera, A.F., & Thiruvengadam, N. Cost Effectiveness of Second-Line Axicabtagene ciloleucel in Relapsed Refractory Diffuse Large B-cell Lymphoma. Blood. 2022 Aug 1:blood.2022016747. PMID: 35914220.
  • Kambhampati, S., Saumoy, M., Schneider, Y., Pak, S., Budde, L.E., Mei, M.G., Siddiqi, T., Popplewell, L., Wen, Y.P., Zain, J., Forman, S.J., Kwak, L.W., Rosen, S.T., Danilov, A.V., Herrera, A.F., & Thiruvengadam, N. Cost Effectiveness of Polatuzumab Vedotin Combined with Chemoimmunotherapy in Untreated Diffuse Large B-cell Lymphoma. Blood. 2022 Jun 14:blood.2022016624. doi: 10.1182/blood.2022016624. Epub ahead of print. PMID: 35700381.
  • Han, Z., Estephan, R.J., Wu, X., Su, C., Yuan, Y.C., Qin, H., Kil, S.H., Morales, C., Schmolze, D., Sanchez, J.F., Tian, L., Yu, J., Kortylewski, M., Rosen, S.T., & Querfeld, C. MicroRNA Regulation of T-Cell Exhaustion in Cutaneous T Cell Lymphoma. J Invest Dermatol. 2022 Mar;142(3 Pt A):603-612.e7. PMID: 34774537; PMCID: PMC8860868.
  • Herek, T.A., Bouska, A., Lone, W., Sharma, S., Amador, C., Heavican, T.B., Li, Y., Wei, Q., Jochum, D., Greiner, T.C., Smith, L., Pileri, S., Feldman, A.L., Rosenwald, A., Ott, G., Lim, S.T., Ong, C.K., Song, J., Jaffe, E.S., Wang, G.G., Staudt, L., Rimsza, L.M., Vose, J., d'Amore, F., Weisenburger, D.D., Chan, W.C.*, & Iqbal, J.* DNMT3A mutations define a unique biological and prognostic subgroup associated with cytotoxic T cells in PTCL-NOS. Blood. 2022;140(11):1278-1290. PMID: 35639959. *co-corresponding authors
  • Siddiqi, T., Soumerai, J.D., Dorritie, K.A., Stephens, D.M., Riedell, P.A., Arnason, J., Kipps, T.J., Gillenwater, H.H., Gong, L., Yang, L., Ogasawara, K., Thorpe, J., & Wierda, W.G. Phase 1 TRANSCEND CLL 004 study of lisocabtagene maraleucel in patients with relapsed/refractory CLL or SLL. Blood. 2022;139(12):1794-1806. PMID: 34699592.
  • Wang, X., Dong, Z., Awuah, D., Chang, W.C., Cheng, W.A., Vyas, V., Cha, S.C., Anderson, A.J., Zhang, T., Wang, Z., Szymura, S.J., Kuang, B.Z., Clark, M.C., Aldoss, I., Forman, S.J., Kwak, L.W., & Qin, H. CD19/BAFF-R dual-targeted CAR T cells for the treatment of mixed antigen-negative variants of acute lymphoblastic leukemia. Leukemia. 2022;36(4):1015-1024. PMID: 35039637; PMCID: PMC8983465.