City of Hope’s Podcast on Cancer Research Breakthroughs
"On the Edge of Breakthrough: Voices of Cancer Research" takes you inside the world of cancer treatment and research at City of Hope® and beyond. Hosted by Sumanta (Monty) Kumar Pal, M.D., FASCO, an internationally recognized leader in the area of genitourinary cancers and co-director of City of Hope's Kidney Cancer Program, this podcast features exclusive conversations with the experts driving the latest scientific discoveries and lifesaving therapies. Whether you're a health care professional, researcher or simply passionate about the fight against cancer, you won't want to miss an episode. Check out the trailer.
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Writing the score to a cure: Dr. Steven Rosen, on a life of science, song and care
Nov. 10, 2026
Steven Rosen, M.D., was just 37 when he became a cancer center director. In this episode of "On the Edge of Breakthrough," the emeritus director of the City of Hope Cancer Center Duarte, reflects on a career spanning research, patient care and cancer center leadership. He shares how early work with monoclonal antibodies shaped his research and how he eventually brought that leadership experience to City of Hope.
What does it take to make advanced cancer care, clinical trials and specialized therapies available to more patients?
In this "On the Edge of Breakthrough" episode, Alan Bryce, M.D., Chief Clinical Officer of City of Hope Arizona, and Kristen Higgins, M.D., Chief Clinical Officer of City of Hope Atlanta, discuss how City of Hope is expanding access to academic cancer medicine in regions that have historically had limited access to it.
In the Season 5 debut of "On the Edge of Breakthrough," City of Hope CEO Robert Stone openly shares the experiences that shaped his career and ultimately led him to the organization 30 years ago. He reveals how a visit to the Duarte campus changed his perspective and set him on a career path he never expected to take.
In this special episode of "On the Edge of Breakthrough: Voices of Cancer Research," Sumanta (Monty) Kumar Pal, M.D., F.A.S.C.O., sits down onsite at the 2026 American Society of Clinical Oncology (ASCO) Annual Meeting with three City of Hope leaders to discuss the research drawing attention across the global oncology community. Alan Bryce, M.D., Kristin Higgins, M.D., and Joseph Mikhael, M.D., share findings they are watching most closely and what those developments could mean for patients and the future of cancer care.
In this episode of "On the Edge of Breakthrough: Voices of Cancer Research," Leo Wang, M.D., Ph.D., pediatric oncologist, Clinical Director of the Gene Therapy Program and Director of the City of Hope Alpha Clinic, discusses the realities of caring for children with cancers that still have few effective treatments. He reflects on what it takes to begin changing those realities for patients and families.
In this episode of "On the Edge of Breakthrough: Voices of Cancer Research," Christine Brown, Ph.D., Deputy Director of the T Cell Research Laboratory at City of Hope, joins Monty Pal, M.D., F.A.S.C.O., to discuss how years of research in glioblastoma, one of the most aggressive and difficult brain cancers, are helping scientists rethink how CAR T cell therapy could effectively treat solid tumors.
In this episode of "On the Edge of Breakthrough: Voices of Cancer Research," John Carpten, Ph.D., Chief Scientific Officer at City of Hope, discusses the evolution of cancer genomics — how early genome mapping enabled today’s targeted approaches and what infrastructure and equity considerations will determine what comes next.
In this episode of "On the Edge of Breakthrough: Voices of Cancer Research," Anna Wu, Ph.D., chair of the Department of Immunology and Theranostics at City of Hope, joins host Monty Pal, M.D., for an engaging discussion on how innovations in antibody engineering and imaging are improving clinicians’ ability to visualize tumors and guide more effective treatment strategies.
In this episode of "On the Edge of Breakthrough: Voices of Cancer Research," Stacy W. Gray, M.D., A.M., Director of Clinical and Scientific Strategy and Vice President of System Strategy at City of Hope, joins Monty Pal, M.D., F.A.S.C.O., for an engaging discussion on how precision medicine and AI are transforming cancer care — and why elevating the patient voice is key to driving progress.
In this episode of "On the Edge of Breakthrough: Voices of Cancer Research," Monty Pal, M.D., F.A.S.C.O., welcomes Marcel van den Brink, M.D., Ph.D., President of City of Hope Los Angeles and City of Hope National Medical Center, Chief Physician Executive and the Deana and Steve Campbell Physician Executive Distinguished Chair.