Mass Spectrometry Publications

The following recent publications illustrate the technical capabilities of the laboratory and a variety of collaborative projects.

Analysis of recurrently protected genomic regions in cell-free DNA found in urine
Markus H, Zhao J, Contente-Cuomo T, Stephens MD, Raupach E, Odenheimer-Bergman A, Connor S, McDonald BR, Moore B, Hutchins E, McGilvrey M, de la Maza MC, Van Keuren-Jensen K, Pirrotte P, Goel A, Becerra C, Von Hoff DD, Celinski SA, Hingorani P, Murtaza M. Sci Transl Med. 2021 Feb 17;13(581):eaaz3088. doi: 10.1126/scitranslmed.aaz3088. PMID: 33597261.

Defining the Caprin-1 interactome in unstressed and stressed conditions
Lucas Vu, Asmita Ghosh, Chelsea Tran, Walters Aji Tebung, Hadjara Sidibé, Krystine Garcia-Mansfield, Victoria David-Dirgo, Ritin Sharma, Patrick Pirrotte, Robert Bowser, Christine Vande Velde bioRxiv 2021.01.06.425453.

Shotgun proteomics coupled to nanoparticle-based biomarker enrichment reveals a novel panel of extracellular matrix proteins as candidate serum protein biomarkers for early-stage breast cancer detection
Fredolini C, Pathak KV, Paris L, Chapple KM, Tsantilas KA, Rosenow M, Tegeler TJ, Garcia-Mansfield K, Tamburro D, Zhou W, Russo P, Massarut S, Facchiano F, Belluco C, De Maria R, Garaci E, Liotta L, Petricoin EF, Pirrotte P. Breast Cancer Res. 2020 Dec 2;22(1):135. doi: 10.1186/s13058-020-01373-9. PMID: 33267867; PMCID: PMC7709252.

A Multifunctional LNAOligonucleotide-Based Strategy Blocks AR Expression and TransactivationActivity in PCa Cells
Castanotto D, Zhang X,Rüger J, Alluin J, Sharma R, Pirrotte P, Joenson L, Ioannou S, Nelson MS,Vikeså J, Hansen BR, Koch T, Jensen MA, Rossi JJ, Stein CA. . Mol Ther Nucleic Acids. 2020 Oct 27;23:63-75. doi:10.1016/j.omtn.2020.10.032. PMID: 33335793; PMCID: PMC7723773.

Proteomic analysis identifies plasma correlates of remote ischemic conditioning in the context of experimental traumatic brain injury
Saber M, Pathak KV, McGilvrey M, Garcia-Mansfield K, Harrison JL, Rowe RK, Lifshitz J, Pirrotte P. Sci Rep. 2020 Jul 31;10(1):12989. doi: 10.1038/s41598-020-69865-4. PMID: 32737368; PMCID: PMC7395133.