Top Cancer Treatment and Research Center | City of Hope

City of Hope^®, one of the largest and most advanced cancer research and treatment organizations in the United States, with a 100+ year legacy, was recognized as one of the nation’s top hospitals for cancer care, according to U.S. News & World Report’s 2025-26 rankings.

We bring breakthroughs from the laboratory to our patients with lifesaving speed – treating cancer with leading-edge technologies, innovative treatments and expert care personalized to each patient’s needs.

And we treat patients across the United States through our national footprint of cancer centers. Learn about our cancer centers by exploring the links below.

Our Cancer Centers

Atlanta Area

City of Hope Chicago

Chicago Area

Los Angeles Area

NCI-Designated Comprehensive Cancer Center

Orange County Area

City of Hope Phoenix Cancer Center building

Phoenix Area

NCI's Top Designation for Cancer Centers

Our National Cancer Center near Los Angeles is a National Cancer Institute (NCI)-Designated Comprehensive Cancer Center. This designation recognizes City of Hope as a national leader in cancer care and an institute dedicated to transforming research into new, innovative treatments for cancer patients across the country and world.

NCI Designated Comprehensive Cancer Graphic

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Walk for Hope 2026

Walk for Hope is a nationwide cancer-ending movement with events this fall
near Los Angeles, Orange County, Chicago, Atlanta, Phoenix and Las Vegas

Patient-Focused Care

Our reputation for groundbreaking discoveries, innovative treatments and compassionate care make us a leader in the fight to help patients here and around the world conquer cancer, diabetes, HIV/AIDS and other life-threatening diseases.

A group of City of Hope doctors providing patient care together

Cancers and Conditions We Treat

Refer a Patient to City of Hope

Forward-Focused Research

Our infrastructure and collaborative energy sets us apart. By having scientists, treatment staff and manufacturing facilities side-by-side, our treatment advances can travel from laboratory to patient with lifesaving speed.

A technician working in a lab

Explore Our Research

Search Clinical Trials

Read Latest News

Hope-Inspired Learning

As a leading research institute, our academic programs look beyond the standard treatments of today, providing educational opportunities that explore the latest advancements in research and therapies.

Graduation ceremony at the Beckman Research Institute

Explore Academics & Training

Irell & Manella Graduate School

FIND A CITY OF HOPE DOCTOR

City of Hope is home to many of the nation's leading cancer doctors. Find the right one for your patient’s needs.

FIND A CITY OF HOPE LOCATION

Headquartered in Duarte, California, with locations across the United States, our unique approach to care is available in your community.

HOW TO REFER A PATIENT

We're here to help and welcome the opportunity to partner with you in providing your patients with the latest treatment innovations.

PHYSICIAN CAREERS

Join a world leader in treating, researching and preventing life-threatening diseases, including cancer, diabetes and HIV/AIDS.

Hope Matters

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A cancer cell being attacked by precision medicine inhibitors

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CAR T cell therapy image of one cell attacking another

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News and Stories of Hope

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The Next Frontier of Cancer Prevention and Care: The Microbiome

City of Hope Convenes HHS Sec. Robert F. Kennedy Jr., NIH Dir. Jay Bhattacharya, and Nation’s Leading Cancer Centers for Symposium to Advance Microbiome Science

City of Hope Researchers to Share New Immunotherapy and Precision Medicine Insights Across Cancer Types at ASCO 2026

Both Facing Cancer, a Navy Sailor and His Mom Became Each Other’s Lifeline

City of Hope Orange County

Both Facing Cancer, a Navy Sailor and His Mom Became Each Other’s Lifeline

Gunner’s Mate Jay Pena crossed an ocean to be there for his mother’s cancer surgery. Then his own fight began.

Patient Stories

Give Hope

You can accelerate leading-edge research and help provide compassionate patient-care.