Downtown Chicago

City of Hope® Cancer Care Downtown Chicago offers patients in and around Chicago consultations, treatments and other cancer care services in an outpatient setting, delivered by a team of experts who work closely with one another to understand each patient’s individual diagnosis and needs. Whether you’ve been recently diagnosed or you’re seeking a second opinion, our Downtown Chicago outpatient care center offers expertise that comes from working exclusively with cancer patients.

41.8909992, -87.6204582

160 Upper E. Illinois St.
Chicago, IL 60611
New Patients
Current Patients

Weekdays, 7:30 a.m. to 4 p.m.

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City of Hope cares for patients from prevention through survivorship by pairing our expertise in numerous cancers and conditions with world-class technologies and services.

City of Hope Downtown Chicago Parking










Parking is available at the Cityfront Garage located at 240 E. Upper Illinois St., Chicago, just east of the outpatient care center. Pedestrian elevators are in the southwest corner of the garage. Once you exit the garage, walk west on Illinois Street and cross St. Clair Street. The entrance to the outpatient care center will be on your right. Parking validation is available at the outpatient care center.

Public transportation options are also available close to the outpatient care center. Go to to determine which option meets your needs.

Downtown Chicago map






City of Hope | Downtown Chicago accepts a variety of insurance plans. If you’re interested in learning more about becoming a patient, we can begin the insurance verification process immediately by obtaining your benefits information and contacting your insurance provider.

To get started or to find out more about becoming a patient, please call us.



Explore City of Hope | Downtown Chicago

Located in the Streeterville neighborhood, City of Hope | Downtown Chicago offers patients in and around Chicago convenient access to personalized cancer care and state-of-the-art technologies. 

Two visitors receiving help at Guest Services desk

Contact City of Hope

We’re here for you. Contact us and we’ll answer any questions.