Orange County Newsroom

A New City of Hope Orange County Report Reveals Concerning Trends About Cancer in Younger Adults in Southern California

City of Hope Orange County, the most advanced cancer research and treatment organization in Orange County, has released a report that evaluates the cancer incidence rate in people ages 18 and 49 in Orange County and Southern California amid a national epidemic of early-onset cancer diagnoses.

In the News

After fitness influencer's shock death, experts reveal subtle early signs that are too often ignored... and lifestyle tweaks that can PREVENT it

June 19, 2026

A worrying trend shows stomach cancer diagnoses rising in Americans under 50, reversing a long decline. Lifestyle factors such as processed foods, alcohol and antibiotic use are implicated. Early detection is challenging due to vague symptoms often dismissed as minor issues. City of Hope's Yanghee Woo, M.D.,observes many young patients and stresses that while difficult to treat, advances in targeted therapies and immunotherapy offer improved outcomes.

Evaluating Worldwide Disparities in Bladder Cancer Clinical Trial Availability

June 16, 2026

City of Hope's Sumanta Kumar Pal, M.D. and colleagues found that bladder cancer clinical trials are concentrated in high-income countries. Their study, published in Cancers, analyzed 611 trials from 2019-2024, revealing 75.1% were HIC-only. Non-HIC trials had lower enrollment and less pharmaceutical funding. Mixed-income trials, while expanding access, were HIC-led and require balanced sponsorship and early-phase research to address global disparities in bladder cancer care.

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Press Releases & Statements

Sept. 13, 2022 | City of Hope Receives $25 Million Gift From Argyros Family to Eradicate Cancer and Advance Its Lifesaving Mission in Orange County, Calif.

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