CAR-T Cell Clinical Trials

City of Hope’s comprehensive CAR-T program is addressing some of the hardest-to-treat cancers by accelerating innovative clinical research approaches. Currently, we have many ongoing trials with additional trials expected to open in the new year.

Ongoing trials

Ongoing CAR-T clinical research initiated at City of Hope includes trials in:


Partner trials

City of Hope is partnering with global biopharmaceutical companies on the following ongoing trials:

New trials

New clinical trials initiated at City of Hope opening in the coming months and in the coming year include:
  • Solid tumors
    • HER2-positive breast cancer that has metastasized to the brain
    • Prostate cancer
  • Blood cancers
    • Multiple myeloma
    • The rare disease amyloidosis


Preclinical CAR-T research

City of Hope is also conducting preclinical CAR-T research in solid tumors for ovarian, head and neck, cervical and pancreatic cancers.