Immunotherapy Is Crucial to Fighting Cancer

City of Hope is one of the few institutions in the nation pioneering immunotherapy through research, clinical trials and collaborations with other academic researchers and global biopharmaceutical companies.

Currently, chimeric antigen receptor (CAR) T cell immunotherapy is one of the most promising approaches to defeating cancer — and it does so by activating your body to fight cancer cells on its own. Learn more by watching the videos below.

What is CAR T Cell Therapy (Animation)

CAR T cell therapy is one way City of Hope scientists are empowering a patient’s own immune system to fight cancer.

Novel City of Hope-Developed Oncolytic Virus Targets Hard-to-Treat Tumors

A cancer-killing virus that City of Hope scientists developed could one day improve the immune system’s ability to eradicate tumors in colon cancer patients.

Combination CAR T Oncolytic Virus Immunotherapy Kills Tumors

City of Hope scientists have combined two potent immunotherapies — an oncolytic virus and chimeric antigen receptor (CAR) T cell therapy — to target and eradicate solid tumors.

Lymphoma Survivor Chuck Fata Is Happy for Every Single Day

Chuck Fata had tried every treatment possible for the aggressive blood cancer he was fighting — diffuse large B cell lymphoma — by the time he turned his hopes to an innovative treatment he had never heard of, chimeric antigen receptor (CAR) T therapy.

Scorpion Venom to Target Brain Tumors

City of Hope scientists have developed and tested the first chimeric antigen receptor (CAR) T cell using chlorotoxin, a component of scorpion venom, to direct T cells to target brain tumor cells.