Ma J, Luong A, Doan A, Lin TY, Ji L, Wang CP, Yoon Sj, Rushing T, Duong A, Villa M, Parekh C. T-Cell Dysfunction during Blinatumomab Therapy in Pediatric Acute Lymphoblastic Leukemia. Blood Adv. 2025 Aug 12; doi: 10.1182/bloodadvances.2025015894
Jambon S, Sun J, Barman S, Muthugounder S, Bito XR, Shadfar A, Kovach AE, Wood BL, Thoppey Manoharan V, Morrissy AS, Bhojwani D, Wayne AS, Pulsipher MA, Kim YM, Asgharzadeh S, Parekh C, Moghimi B. CD33-CD123 IF-THEN Gating Reduces Toxicity while Enhancing the Specificity and Memory Phenotype of AML-Targeting CAR-T Cells. Blood Cancer Discov. 2025 Jan 8;6(1):55-72. doi: 10.1158/2643-3230.BCD-23-0258.
Parker RS, Le J, Villa M, Luong A, Tsen YL, Lee Y, Doan A, Aguayo-Hiraldo P, Pannaraj PS, Yeon SJ, Wallace W, Armstrong A, O'Gorman MR, Dien Bard J, Parekh C. COVID-19 vaccinated Children, Adolescents, and Young Adults with Acute Lymphoblastic Leukemia show Spike Protein reactive neutralizing antibodies and/or multifunctional T-cells. Int J Cancer. 2024 Jul 15;. doi: 10.1002/ijc.35096.
Ruan Y, Kim HN, Ogana HA, Wan Z, Hurwitz S, Nichols C, Abdel-Azim N, Coba A, Seo S, Loh YE, Gang EJ, Abdel-Azim H, Hsieh CL, Lieber MR, Parekh C, Pal D, Bhojwani D, Durden DL, Kim YM. Preclinical Evaluation of a Novel Dual Targeting PI3K$\delta$/BRD4 Inhibitor, SF2535, in B-Cell Acute Lymphoblastic Leukemia. Front Oncol. 2021;11:766888. doi: 10.3389/fonc.2021.766888. eCollection 2021. PMID: 34926269.
Sun V, Sharpley M, Kaczor-Urbanowicz KE, Chang P, Montel-Hagen A, Lopez S, Zampieri A, Zhu Y, de Barros SC, Parekh C, Casero D, Banerjee U, Crooks GM. The Metabolic Landscape of Thymic T cell Development In Vivo and In Vitro. Frontiers in Immunology. 12;2993, 2021. Published online July 28,2021, PMID pending.
Le J, Park JE, Ha VL, Luong A, Branciamore S, Rodin AS, Gogoshin G, Li F, Loh YHE, Camacho V, Patel SB, Welner RS, Parekh C. Single-Cell RNA-Seq Mapping of Human Thymopoiesis Reveals Lineage Specification Trajectories and a Commitment Spectrum in T Cell Development. Immunity. 52(6);1105-18, 2020. PMID: 32553173. PMCID: PMC7388724.
Gang EJ., Kim HN, Hsieh YT, Ruan Y, Ogan, HA, Lee S, Pham J, Geng H, Park E, Klemm L, Willman CL, Carroll WL, Mittelman SD, Orgel E, Oberley MJ, Parekh C, Abdel-Azim H, Bhojwani D, Wayne AS, De Arcangelis A, Georges-Labouesse E, Wayner E, Bonig H, Minasyan A, Ten Hoeve J, Graeber TG, Müschen M, Heisterkamp N, Kim YM. Integrin $\alpha$6 mediates the drug resistance of acute lymphoblastic B-cell leukemia. Blood. 136(2):210-223, 2020. PMID: 32219444. PMCID: PMC7357190.
Ha VL, Luong A, Casero D, Li F, Malvar J, Kim YM, Bhatia R, Crooks GM, Parekh C. The T-ALL related gene BCL11B regulates the initial stages of human T-cell differentiation. Leukemia. 31(11):2503–14, 2017. PMID: 28232744 PMCID: PMC5599326.
Adam E, Kim HN, Gang EJ, Schnair C, Lee S, Lee S, Khazal S, Kosoyan O, Konopleva M, Parekh C, Bhojwani D, Wayne AS, Abdel-Azim H, Heisterkamp N, Kim YM. The PI3K$\delta$ Inhibitor Idelalisib Inhibits Homing in an in Vitro and in Vivo Model of B ALL. Cancers (Basel). 2017. PMID: 28891959 PMCID: PMC5615336.
Casero D, Sandoval S, Seet CS, Scholes J, Zhu Y, Ha VL, Luong A, Parekh C** (co-last author) and Crooks GM**. Global mapping and classification of long non-coding RNAs during human lymphoid commitment reveals transcriptional divergence of B and T lineages. Nature Immunology. 16(12):1282-91, 2015. PMID: 26502406 PMCID: PMC4653072. ** These authors contributed equally to this work and are co-corresponding authors.
Lu Z, Pannunzio NR, Greisman HA, Casero D, Parekh C, Lieber MR. Convergent BCL6 and lncRNA Promoters Demarcate the Major Breakpoint Region for BCL6 Translocations. Blood 126(14):1730-1, 2015. PMID: 26276666 PMCID: PMC4591794.
Chung B, Montel-Hagen A, Ge S, Blumberg G, Kim K, Klein S, Zhu Y, Parekh C, Balamurugan A, Yang OO, Crooks GM. Engineering the human thymic microenvironment to support thymopoiesis in vivo. Stem Cells. 32(9):2386-96, 2014. PMID: 24801626 PMCID: PMC4138233.
Kim WS, Zhu Y, Deng Q, Chin CJ, He CB, Grieco AJ, Dravid GG, Parekh C, Hollis RP, Lane TF, Bouhassira EE, Kohn DB, Crooks GM. Erythropoiesis from human embryonic stem cells through erythropoietin-independent AKT signaling. Stem Cells. 32(6):1503-14, 2014. PMID: 24677652 PMCID: PMC4037366.
Corselli M, Chin CJ, Parekh C, Sahaghian A, Wang W, Ge S, Evseenko D, Wang X, Montelatici E, Lazzari L, Crooks GM, Péault B. Perivascular support of human hematopoietic stem/ progenitor cells. Blood. 11;121(15):2891-901, 2013. PMID: 23412095 PMCID: PMC3707421.