City of Hope® has one of the largest prostate cancer programs in California and the West, and our outcomes rank higher than most U.S. institutions in the SEER national registry.

Our flagship National Cancer Institute (NCI) comprehensive center in Duarte, California, has been recognized as having one of the nation’s top 5 hospitals for cancer care, according to U.S. News & World Report’s 2024-25 rankings. 

City of Hope is a hub of leading-edge research on early diagnosis and screening, prevention, health disparities, risk factors, and quality-of-life issues related to treatment. Our bench-to-bedside approach ensures that you receive the most innovative and effective care. We are committed to providing you with the best possible care and treatment, and we enroll patients in lifesaving clinical trials. Choose City of Hope for the best care for prostate cancer.

Prostate Cancer Care in Los Angeles

At City of Hope, we understand the fear and uncertainty that a prostate cancer diagnosis can bring. Our physicians work closely with you and your loved ones to determine the best treatment options based on your diagnosis and health goals. Whether it's surgery, radiation therapy or drug therapy, we will provide you with highly advanced and effective treatments, such as robotically assisted prostatectomies.

We're committed to creating individualized treatments that aim to preserve urinary and sexual function wherever possible, so you can feel confident in the care you receive.

City of Hope's locations include its Los Angeles (Duarte) cancer center and a network of clinical care locations across Southern California.
 

What Sets Our Los Angeles-Area Prostate Cancer Program Apart?

  • At City of Hope, we understand that every patient and their needs are unique. That's why our cancer care teams are made up of a range of specialists who work together to determine the best treatment options for you. Our multidisciplinary approach ensures that you receive personalized, targeted care that offers the best possible health outcomes.
  • With decades of experience using the state-of-the-art da Vinci robotic surgery system, our team of experts can provide minimally invasive surgical options that can help improve outcomes and make recovery faster and more comfortable. 
  • Our team of experts also collaborates with precision medicine, using genetic counseling and genomic testing to provide you with the most comprehensive cancer care available. 
  • We use the latest technology, such as mpMRI and fusion prostate biopsy, to enhance tumor detection and personalize treatment plans. 
  • At City of Hope, we provide long-term follow-up with prostate cancer survivors to detect and manage long-term effects and improve their quality of life. With telehealth or in-person appointments scheduled within five to seven days, you can rest assured that you'll receive the care you need, when you need it.
  • Our five-year survival rate is close to 100%, and we have superior outcomes for prostate cancer stages 1-4.

Prostate Cancer Clinical Trials

Our clinical trials aim to improve prostate cancer outcomes across the spectrum of the disease, from early to late stage. We're using a range of methods to treat prostate cancer, including focused ultrasound to destroy cancer cells, identifying and incorporating biomarkers for better detection of prostate cancer development, progression and recurrence. We're doing this with neural stem cells to target and deliver cancer-fighting drugs to prostate cancer cells throughout the body, and new imaging methods to detect microscopic disease outside the prostate. We also use reengineered immune cells to target and attack prostate cancer throughout the body and examine the benefits of surgery for patients with metastatic prostate cancer. Additionally, we use natural therapies, such as white mushroom powder, to help prevent prostate cancer recurrence.

Our Los Angeles-Area Prostate Cancer Program Recognitions

City of Hope is ranked among the Highest Performing Hospitals for Prostate Cancer Surgery by U.S. News & World Report 2024-25
City of Hope is ranked among the Highest Performing Hospitals in Urology by U.S. News & World Report 2024-25

City of Hope is a nationally recognized leader in researching and treating urologic cancers, and we consistently rank among U.S. News and World Report’s best hospitals for cancer in the United States, with consecutive rankings for nearly two decades. 

This year, U.S. News rated City of Hope Duarte as “high performing” for prostate cancer surgery and a top-50 best hospital in urology.

 

Our Los Angeles-Area Prostate Cancer Experts

Prostate Cancer Leadership

Doctor Tanya Dorff

Tanya Barauskas Dorff, M.D., is a medical oncologist and professor in the Department of Medical Oncology & Therapeutics Research.

Lau Clayton LAX
Clayton S. Lau, M.D.
Urologic Surgeon; Pauline & Martin Collins Family Chair in Urology

Clayton Lau, M.D., is chief of the Division of Urology and Urologic Oncology and an expert in prostate cancer.

Make an Appointment with Our Los Angeles-Area Prostate Cancer Team

Expertise Matters

The world-renowned team at City of Hope offers a deep understanding of the latest prostate cancer treatments. Our expertise comes from treating urologic cancers, including rare and complex cases, every day. 
 

Call to become a patient, get a second opinion, or make a referral.

Researchers at the Center for Clinical Research at City of Hope

Prostate Cancer Stories