Discover the transformative care at City of Hope® Cancer Center Duarte for colorectal, stomach (gastric), pancreatic, liver, gallbladder, bile duct, esophageal and small intestine cancers, as well as gastrointestinal carcinoid tumors, in a compassionate, patient-centered environment.

Our team offers personalized care that is tailored to your unique needs, ensuring you feel understood and valued. Recognized as one of the nation's top cancer research and treatment centers by U.S. News & World Report for over a decade, we are also designated as a comprehensive cancer center by the National Cancer Institute.

Our comprehensive approach to treating gastrointestinal cancers involves a team of experts, including surgeons, oncologists, gastroenterologists, radiologists and pathologists who specialize in advanced and recurrent diseases. Our approach includes molecular and genetic testing to find the most effective therapies. Our commitment is to treat your cancer, deliver optimal survival outcomes and restore your overall well-being. When you choose City of Hope, you select a dedicated partner in your journey to wholeness.

By providing comprehensive care for gastrointestinal cancers, City of Hope aims to help you achieve a long and cancer-free life. Our focus is not only on leading-edge treatments and innovation; we are committed to restoring your overall well-being. Our multidisciplinary team collaborates closely at every stage, ensuring seamless and coordinated care.

Our highly skilled surgeons are experts in leading-edge techniques such as minimally invasive, laparoscopic and robotic surgery, supported by the latest therapeutic and radiological advancements. As a result, patients experience reduced discomfort, blood loss and quicker recovery times, with some even able to return home within 24 hours after surgery.

• We are renowned for our leadership, innovation and experience in liver cancer surgeries, with a strong track record for safety and long-term outcomes. Our needle- and catheter-based therapies effectively treat liver tumors without major incisions. Our Division of Colorectal Surgery is committed to precision, such as preserving the sphincter muscle and avoiding permanent colostomies. Our gastrointestinal expertise extends to D2 lymphadenectomy and procedures such as ablation and embolization.
• We employ leading-edge radiation therapy, chemotherapy and immunotherapy techniques, such as helical TomoTherapy®, to target tumors precisely while preserving healthy tissue.
• We specialize in hepatic arterial infusion (HAI), a method that delivers cancer-fighting drugs directly to the tumor site for maximum effectiveness.
• We offer innovative approaches: hyperthermic intraperitoneal chemotherapy (HIPEC) and pressurized intraperitoneal aerosolized chemotherapy (PIPAC) that involve surgically removing widespread cancer and delivering targeted, heated chemotherapy directly to the abdomen.
• Our leading-edge genetic targeting identifies a tumor's specific biology and tailors treatments to halt its growth. Our specialized expertise in hereditary/familial cancer syndromes, employing next-generation DNA sequencing to assess current and future risks for all potentially affected family members, allows us to personalize drug therapy according to the molecular profile of specific cancer types.
• Our patients can take advantage of our wide range of gastrointestinal cancer clinical trials, providing access to the latest cancer treatments and tests; many promising therapies are exclusively available to City of Hope patients. Our clinical trials include combined immunotherapy with radiation therapy to strengthen the immune system's cancer-fighting response.
• We offer comprehensive supportive care services to aid patients and their loved ones in maintaining wellness, helping families adjust to post-treatment diet and lifestyle changes. Our palliative procedures are designed to enhance quality of life.

U.S. News & World Report has ranked City of Hope Duarte as a “High Performing Hospital” for colon cancer surgery and as one of America’s top cancer hospitals overall for nearly two decades.