Preparing for your first appointment City of Hope Orange County

Preparing for Your First Appointment


By choosing City of Hope Orange County, you are in the care of experts who are among the top cancer specialists in the nation. We will do everything possible to deliver the best treatment options and ensure you feel confident about your care.

Below are a few details for your upcoming appointment. Should you have any further questions regarding your new patient appointment, please feel free to contact the City of Hope Orange County Lennar Foundation Cancer Center Monday-Friday from 8:00 am to 5:00 pm at 949-671-4673 (HOPE).
About Your Appointment
Our team of experts is looking forward to welcoming you to the City of Hope Orange County Lennar Foundation Cancer Center.

City of Hope Orange County Lennar Foundation Cancer Center

1000 FivePoint, Irvine, CA 92618
Tel: 949-671-4673
City of Hope Orange County Lennar Foundation Cancer Center Campus Map


We are a new medical facility in Irvine's Great Park with new roads.  We recommend using Google Maps for navigation to our location. 
NOTE: Other mapping apps are NOT up to date.

Enter the City of Hope Orange County Lennar Foundation Cancer Center from Barranca Parkway at Launch.  Turn left onto FivePoint and follow the signs to the valet parking or self-park in the structure.


Complimentary Self-Parking

The center’s parking structure can be accessed by turning onto Launch Road from Barranca Parkway, then turning left onto FivePoint street. Self-parking is available in the structure on your left. The upper level of the parking structure is designated for patients and visitors, along with unrestricted parking within the structure. EV parking is available in the structure on a first come, first serve basis. The parking structure is open Monday-Friday from 8 a.m. – 5 p.m. 

Valet Parking

For valet parking, continue to drive toward the main entrance of the building. A valet parking attendant will meet you at your vehicle underneath the covered entrance. It is a standard rate of $4 and $2 for those with an accessible placard. 

MyCityofHope Patient Portal

Why is the Patient Portal important?
With MyCityofHope Patient Portal, you can request an appointment, ask for prescription refill(s), view clinical notes, access most recent test results, and communicate with your care team. You can also find driving and walking directions from the appointment detail page. 

How do I sign up for MyCityofHope Patient Portal?
To sign up, you will need the activation code emailed to you. You can also scan the QR code in the email with your iPhone or Android. Then, visit

  1. Click the “New User Sign Up” box.

  2. Enter your MyCityofHope activation code. Please note:  activation codes expire 45 days after being issued. You may also find the activation code on your City of Hope billing statements. 

  3. Follow the prompts to complete your registration. 

If you have questions or need a new activation code, please call our MyCityofHope help desk at 844-777-4673. Our technical support team is available at this number 24/7. To learn more and to sign up, visit    

Pre-Appointment Checklist

Please review our visitor and COVID-19 (coronavirus) policies:  

To help ensure the health and safety of our patients and staff during this time, City of Hope has the following policy for outpatient visitors/caregivers: ​​​​

  • For all outpatient appointments (at the City of Hope Orange County Lennar Foundation Cancer Center or any of our clinical network sites in OC), patients may have one visitor/caregiver per patient visit. The visitor does not need to be pre-identified prior to the visit.  

  • For pediatric patients under 18, both parents will be allowed for outpatient visits. 

  • For goals of care discussions, up to three visitors will be permitted for a single visit.  

    City of Hope is committed to preventing the spread of COVID-19 – for everyone’s health and safety: 

  • Return home if you have been exposed to COVID-19 or have symptoms. 

  • Masks are required at all times. 

  • Respect social distancing. 

  • Sanitize hands often. 

Should you need more information about our COVID or visitor policies, please visit Call the California COVID-19 Hotline at 833-422-4255 for general questions about COVID-19. 


  •  Please complete the “e-check in” questionnaire available at before your appointment. This questionnaire will be available 7 days prior to your appointment. If you are unable to complete it before your appointment, you will be asked to do this prior to your appointment which could result in a delayed visit. 

Please bring the following items with you to your appointment: 

  • A valid ID (driver’s license, passport, etc.):  For patient safety, you will not be seen by the physician without proper identification  

  • Your current medications in their original containers, or a current list 

  • Any imaging CDs. Please be advised: If you have been instructed to bring imaging CDs or films with you for your appointment, the imaging is required for your consultation, and failure to bring the imaging may result in the rescheduling of your appointment 

Please try to arrive 15-20 minutes before your appointment to allow check-in and document signing before your appointment.  

Again, if you have any questions about your care, please feel free to contact the City of Hope Orange County Lennar Foundation Cancer Center Monday-Friday from 8:00 am to 5:00 pm at 949-671-4673 (HOPE).