HopeSeq Heme Mutations Comprehensive
A next generation sequencing (NGS) based assay designed to target the entire coding sequence of commonly mutated genes in hematologic malignancies.
HopeSeq HemeMutations Gene List
Full-length mutation analysis of 135 genes:
ABL1, ARID1A, ASXL1, ATM, B2M, BCL2, BCL6, BCOR, BCORL1, BIRC3, BRAF, BTK, CALR, CARD11, CBL, CBLB, CCND1, CCND3, CD38, CD3E, CD3G, CD79A, CD79B, CDK4, CDK7, CDKN1B, CDKN2A, CDKN2B, CDKN2C, CEBPA, CHD2, CRBN, CREBBP, CSF3R, CUX1, CXCR4, DDx3x, DIS3, DNMT3A, E2F1, EGFR, EP300, ETV6, EZH2, FBXW7, FGFR3 , FH, FLT3, FAM46C, FOXO1, GATA1, GATA2, GNA13, GNAS, HCK, HRAS, ID3, IDH1, IDH2, IGLL5, IKZF1, IL6, IL7R IRF4, JAK1, JAK2, JAK3, KDM6A, KIT, KMT2A, KMT2C, KMT2D, KRAS, LCK, LMO2, MAPK1, MEF2B, MGA, MIR142, MPL, MYC, MYD88, NFKB2, NOTCH1, NOTCH2, NPM1, NRAS, NTRK1, PAX5, PDCD1, PDGFRA, PHF6, PIGA, PIK3CA, PIK3CD, PIK3CG, PIK3R5, PLCG2, POT1, PRDM1, PTEN, PTK2B, PTPN11, RAD21, RB1, RFC4, RPS15, RUNX1, SETBP1, SF3B1, SMC1A, SMC3, SOCS1, SOCS6, SPI1, SRSF2, STAG2, STAT3, STAT5A, STAT5B, STAT6, SUZ12, TCF3, TET2, TNFAIP3, TP53, TP63, U2AF1, UBR5, WHSC1, WHSC1L1, WT1, XPO1, ZEB1, ZRSR2