Testicular cancer is a highly treatable disease, with a combined survival rate of about 95%. However, testicular cancer is the most common cancer diagnosed in men in their 20s and 30s, and rates for testicular cancer have been increasing in recent decades.
The Testicular Cancer and Germ Cell Tumor Program at City of Hope® offers patients in Southern California access to advanced treatment options for all types of testicular cancer, with a special focus on germ cell tumors — a type of cancer that accounts for 90% of all testicular cancer. The Testicular Cancer and Germ Cell Tumor Program team includes medical, radiation and surgical oncologists, stem cell transplantation experts and other clinicians with expertise in fertility-preserving treatment options. We also offer comprehensive sexual health counseling for those affected by the disease.
For the past 19 years, City of Hope has been named as one of the nation's best hospitals for cancer in U.S. News & World Report’s annual rankings. For 2025-26, these rankings placed City of Hope among the top 10 in the nation for the fourth consecutive year. As a hub of leading-edge research and a designated comprehensive cancer center, we are committed to providing each patient with innovative treatment options and a personalized approach to care.
Testicular Cancer and Germ Cell Tumor Care in Los Angeles and Orange County
Patients who receive care for testicular cancer at City of Hope work closely with a multidisciplinary team of doctors, nurses and supportive care staff, which may include urologists, oncologists, urologic and thoracic surgeons, stem cell transplant physicians, sexual health counselors and social workers.
Because every patient’s diagnosis is unique, we are committed to a patient-first approach to cancer care that ensures that men diagnosed with testicular cancer have access to advanced treatment options. These include minimally invasive surgery, fertility-sparing procedures, radiation therapy and stem cell transplants. Every step of the way, we also take our patients’ goals and preferred outcomes into account and support their physical, sexual and emotional health.
What Sets Our Testicular Cancer and Germ Cell Tumor Program Apart?
Patients who receive care at City of Hope benefit from:
- Our multidisciplinary approach to care, which brings together experts in multiple fields to create a personalized care plan for you
- Minimally invasive surgical options and nerve-sparing surgeries, which reduce the risk of neurologic complications
- Fertility-sparing treatments and strategies, including sperm banking
- Medical oncologists and radiation oncologists with expertise in a wide range of drug therapies and radiation therapies that may be used in combination with surgery
- Stem cell transplants performed by City of Hope’s leading hematopoietic stem cell transplantation program, which may be recommended for patients who might benefit from high-dose chemotherapy treatment
- Sexual health counseling and supportive care from day one, with the goal of helping patients manage issues related to fertility, sexual health, urinary health and the physical and emotional side effects of cancer and its treatment
- Access to clinical trials that offer leading-edge treatment strategies
Testicular Cancer and Germ Cell Tumor Clinical Trials
As a leader in clinical trials and breakthrough cancer research, City of Hope remains committed to developing new approaches to screening for, preventing and treating testicular cancer. Some of our recent work in testicular cancer and germ cell tumor research includes investigations into new chemotherapy treatments, as well as state-of-the-art and minimally invasive surgical options. If you or a loved one received treatment for testicular cancer at City of Hope, talk to your care team to find out whether you are eligible to enroll in any current clinical trials.
Current trials include:
- Phase 1, First-in-Human, Dose Escalation and Expansion Study to Evaluate the Safety and Tolerability of XmAb541 in Advanced Solid Tumors
- Phase 3 Accelerated BEP Trial
- Testing the Addition of Pedmark to Cisplatin Chemotherapy for Reducing Drug-Induced Ear Damage in Men With Stage II-III Metastatic Testicular Germ Cell Tumors
Recently published research includes:
- Comprehensive Profiling of Cell Surface Proteins in Testicular Germ Cell
- Olaparib Response in a Patient With Platinum-Refractory Germ Cell Tumor Harboring a Somatic BRIP1 Mutation
- Longitudinal Evaluation of Circulating Tumor DNA as a Prognostic Biomarker to Detect Molecular Residual Disease in Germ Cell Tumors
- Multicenter Analysis of High-Dose Chemotherapy Regimens or the Treatment of Patients With Refractory or Recurrent Germ Cell Tumors
- Boosting CAR T Cell With Anti-Tumor mRNA Vaccines
Our Testicular Cancer and Germ Cell Tumor Experts
Testicular Cancer and Germ Cell Tumor Leadership
Ali Zhumkhawala, M.D., is a urologic oncology surgeon specializing in the treatment of prostate, testicular, bladder and kidney cancers.
Alexander Chehrazi-Raffle, M.D., is the assistant professor, department of Medical Oncology & Therapeutics Research.
Meet our Los Angeles-Area Testicular Cancer and Germ Cell Tumor Experts
Tanya Barauskas Dorff, M.D., F.A.S.C.O., is a medical oncologist and professor in the Department of Medical Oncology & Therapeutics Research.
Dr. Abigail Fong, M.D., M.B.A, is an assistant clinical professor in the department of surgery.
Jae Y. Kim, M.D., is the chief of the Division of Thoracic Surgery and an associate professor in the Department of Surgery. Dr. Kim specializes in esophageal cancer and lung cancer, robotic surgery, mesothelioma and thymoma.
Matthew Genyeh Mei, M.D. is a hematologist-oncologist at City of Hope in the Los Angeles area with particular expertise in lymphoma, stem cell transplant and cellular immunotherapy.
Jonathan Yamzon, M.D., is a urologic oncology surgeon and an associate clinical professor of surgery.
Wesley Yip, M.D., is an assistant professor in the Department of Surgery at City of Hope.
Meet our Orange County Testicular Cancer and Germ Cell Tumor Experts
Cory Hugen, M.D., is an associate clinical professor in the Division of Urology and Urologic Oncology in the Department of Surgery at City of Hope Orange County.
Charles B. Nguyen, M.D., is an assistant clinical professor in the Department of Medical Oncology & Therapeutics Research at City of Hope Orange County.
Binh N. Trinh, M.D., Ph.D., is an accomplished thoracic surgeon whose career has been shaped by a lifelong desire to ease suffering and bring hope to patients.
Make an Appointment with Our Team
Our nationally renowned team of testicular and genitourinary cancers experts are committed to offering City of Hope patients access to innovative treatments that are safe and effective, while preserving quality of life and sexual health into survivorship.
If you or a loved one has been diagnosed with testicular cancer or would like a second opinion on a new diagnosis, call us today to make an appointment.
